• Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress 

      Petrovic, Voin; Nepal, Anala; Olaisen, Camilla; Bachke, Siri; Hira, Jonathan; Søgaard, Caroline Krogh; Røst, Lisa Marie; Misund, Kristine; Andreassen, Trygve; Melø, Torun Margareta; Bartosova, Zdenka; Bruheim, Per; Otterlei, Marit (Journal article; Peer reviewed, 2018)
      The use of garlic and garlic-based extracts has been linked to decreased incidence of cancer in epidemiological studies. Here we examine the molecular and cellular activities of a simple homemade ethanol-based garlic extract ...
    • Associations of physical activity and sedentary time with lipoprotein subclasses in Norwegian schoolchildren: The Active Smarter Kids (ASK) study 

      Jones, Paul Remy; Rajalahti, Tarja; Resaland, Geir Kåre; Aadland, Eivind; Steene-Johannessen, Jostein; Anderssen, Sigmund Alfred; Bathen, Tone Frost; Andreassen, Trygve; Kvalheim, Olav Martin; Ekelund, Ulf (Journal article; Peer reviewed, 2019)
      Background and aims: Physical activity is favourably associated with certain markers of lipid metabolism. The relationship of physical activity with lipoprotein particle profiles in children is not known. Here we examine ...
    • Benzoylated uronic Acid building blocks and synthesis of N-uronate conjugates of lamotrigine 

      Esmurziev, Aslan; Reimers, Arne; Andreassen, Trygve; Simic, Nebojsa; Sundby, Eirik; Hoff, Bård Helge (Journal article; Peer reviewed, 2012)
      chemoenzymatic approach towards benzoylated uronic acid building blocks has been investigated starting with benzoylated hexapyranosides using regioselective C-6 enzymatic hydrolysis as the key step. Two of the building ...
    • Benzoylated uronic acid building blocks and synthesis of N-uronate conjugates of lamotrigine 

      Esmurziev, Aslan; Reimers, Arne; Andreassen, Trygve; Simic, Nebojsa; Sundby, Eirik; Hoff, Bård Helge (Journal article; Peer reviewed, 2012)
      A chemoenzymatic approach towards benzoylated uronic acid building blocks has been investigated starting with benzoylated hexapyranosides using regioselective C-6 enzymatic hydrolysis as the key step. Two of the building ...
    • Biomarker discovery using NMR based metabolomics of tissue 

      Grinde, Maria Tunset; Giskeødegård, Guro F.; Andreassen, Trygve; Tessem, May-Britt; Bathen, Tone Frost; Moestue, Siver Andreas (Journal article; Peer reviewed, 2019)
      NMR-based metabolomics has shown promise in the diagnosis of diseases as it enables identification and quantification of metabolic biomarkers. Using high-resolution magic-angle-spinning (HR-MAS) NMR spectroscopy, metabolic ...
    • Effect of Repeated Freeze‒Thaw Cycles on NMR-Measured Lipoproteins and Metabolites in Biofluids 

      Wang, Feng; Debik, Julia; Andreassen, Trygve; Euceda, Leslie R.; Haukaas, Tonje Husby; Cannet, Claire; Schäfer, Hartmut; Bathen, Tone Frost; Giskeødegård, Guro F. (Journal article; Peer reviewed, 2019)
      Metabolic profiling of biofluids by nuclear magnetic resonance (NMR) spectroscopy serves as an important tool in disease characterization, and its accuracy largely depends on the quality of samples. We aimed to explore ...
    • Estrogen receptor α promotes breast cancer by reprogramming choline metabolism 

      Jia, Min; Andreassen, Trygve; Jensen, Lasse; Bathen, Tone Frost; Sinha, Indranil; Gao, Hui; Zhao, Chunyan; Haldosen, Lars-Arne; Cao, Yihai; Girnita, Leonard; Moestue, Siver Andreas; Dahlman-Wright, Karin (Journal article; Peer reviewed, 2016)
      Estrogen receptor α (ERα) is a key regulator of breast growth and breast cancer development. Here, we report how ERα impacts these processes by reprogramming metabolism in malignant breast cells. We employed an integrated ...
    • Identification of Metabolites from 2D 1H-13C HSQC NMR using Peak Correlation Plots 

      Öman, Tommy; Tessem, May-Britt; Bathen, Tone Frost; Bertilsson, Helena; Angelsen, Anders; Hedenström, Mattias; Andreassen, Trygve (Journal article; Peer reviewed, 2014)
      Background Identification of individual components in complex mixtures is an important and sometimes daunting task in several research areas like metabolomics and natural product studies. NMR spectroscopy is an excellent ...
    • New Methods for Preparationof Optically Active Unsaturated Amines 

      Andreassen, Trygve (Doktoravhandlinger ved NTNU, 1503-8181; 2009:12, Doctoral thesis, 2009)
    • The effect of sampling procedures and day-to-day variations in metabolomics studies of biofluids 

      Giskeødegård, Guro F.; Andreassen, Trygve; Bertilsson, Helena; Tessem, May-Britt; Bathen, Tone Frost (Journal article; Peer reviewed, 2019)
      Metabolomics analysis of biofluids is a feasible tool for disease characterization and monitoring due to its minimally invasive nature. To reduce unwanted variation in biobanks and clinical studies, it is important to ...