Blar i NTNU Open på forfatter "Alsøe, Lene"

Viser treff 1-4 av 4

    • SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing 

      Kroustallaki, Pinelopi; Lirussi, Lisa; Carracedo, Sergio; You, Panpan; Esbensen, Qin Ying; Götz, Alexandra; Jobert, Laure; Alsøe, Lene; Sætrom, Pål; Gagos, Sarantis; Nilsen, Hilde (Journal article; Peer reviewed, 2019)
      Telomerase biogenesis is a complex process where several steps remain poorly understood. Single-strand-selective uracil-DNA glycosylase (SMUG1) associates with the DKC1-containing H/ACA ribonucleoprotein complex, which is ...

    • SMUG1 regulates fat homeostasis leading to a fatty liver phenotype in mice 

      Carracedo Huroz, Sergio; Lirussi, Lisa; Alsøe, Lene; Segers, Filip; Wang, Changliang; Bartosova, Zdenka; Bohov, Pavol; Tekin, Nuriye Basdag; Kong, Xiang Yi; Esbensen, Qin Ying; Chen, Liang; Wennerström, Anna Berit; Kroustallaki, Pinelopi; Ceolotto, Deborah; Tönjes, Anke; Berge, Rolf Kristian; Bruheim, Per; Wong, Garry; Böttcher, Yvonne; Halvorsen, Bente; Nilsen, Hilde (Journal article; Peer reviewed, 2022)

    • TiSA: TimeSeriesAnalysis - A pipeline for the analysis of longitudinal transcriptomics data 

      Lefol, Yohan Pierre; Korfage, Tom; Mjelle, Robin; Prebensen, Christian Haugland; Lüders, Torben; Müller, Bruno; Krokan, Hans Einar; Sarno, Antonio; Alsøe, Lene; Berdal, Jan-Erik; Sætrom, Pål; Nilsen, Hilde; Domanska, Diana (Peer reviewed; Journal article, 2023)
      Improved transcriptomic sequencing technologies now make it possible to perform longitudinal experiments, thus generating a large amount of data. Currently, there are no dedicated or comprehensive methods for the analysis ...

    • Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG 

      Alsøe, Lene; Sarno, Antonio; Carracedo Huroz, Sergio; Domanska, Diana Ewa; Dingler, Felix; Lirussi, Lisa; Sengupta, Tanima; Tekin, Nuriye Basdag; Jobert, Laure; Alexandrov, Ludmil B.; Galashevskaya, Anastasia; Rada, Cristina; Sandve, Geir Kjetil; Rognes, Torbjørn; Krokan, Hans Einar; Nilsen, Hilde Loge (Journal article; Peer reviewed, 2017)
      Both a DNA lesion and an intermediate for antibody maturation, uracil is primarily processed by base excision repair (BER), either initiated by uracil-DNA glycosylase (UNG) or by single-strand selective monofunctional ...