Browsing NTNU Open by Author "Afset, Jan Egil"
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A study of local complications of PIVCs after intravenous antibiotic treatment at a tertiary care hospital in Nepal
Berg, Thea Sofie (Master thesis, 2024)Sammendrag Bakgrunn: Flertallet av pasient som er innlagt på sykehus får minst et perifert venekateter (PVK). PVKer er relativt trygge, og komplikasjonsratene er svært lave. Allikevel er det totale antallet komplikasjoner ... -
A systems approach to study immuno- and neuro-modulatory properties of antiviral agents
Zusinaite, Eva; Ianevski, Alexandr; Niukkanen, Diana; Poranen, Minna M.; Bjørås, Magnar; Afset, Jan Egil; Tenson, Tanel; Velagapudi, Vidya; Merits, Andres; Kainov, Denis (Journal article; Peer reviewed, 2018)There are dozens of approved, investigational and experimental antiviral agents. Many of these agents cause serious side effects, which can only be revealed after drug administration. Identification of the side effects ... -
Antimicrobial therapy for bloodstream infections in a low resistance environment: A retrospective observational study
Grøv, Kornelius; Håland, Erling (Master thesis, 2022)Formål: Karakterisere alle blodstrømsinfeksjoner ved et sykehus i Norge i løpet av 2019 med tanke på valg av empirisk antimikrobiell behandling, deeskaleringsstrategier og mortalitet. Metode: Retrospektiv observasjonsstudie ... -
Awareness of cervical cancer and prevalence of human papillomavirus and other sexually transmitted infections among women in rural Nepal.: Implications for future cervical cancer prevention in Nepal
Shakya, Sunila (Doctoral theses at NTNU;2017:87, Doctoral thesis, 2017)Cervical cancer is a leading cause of cancer deaths among women in Nepal. Limited information is available on public awareness on cervical cancer, the prevalence of its causative agents and associated risk factors. No ... -
Characterization of the virulence potential of Staphylococcus condimenti isolated from a patient with severe soft tissue infection
Gabrielsen, Christina; Kols, Nicola Isabelle; Øye, Christian; Bergh, Kåre; Afset, Jan Egil (Journal article; Peer reviewed, 2017)The coagulase-negative bacterium Staphylococcus condimenti and closely related species are commonly isolated from or found in starter cultures of fermented sausage as well as fish and soy sauces, and have traditionally ... -
Comparative genomics of Streptococcus agalactiae from adults with invasive infection
Rønning, Torunn Gresdal (Master thesis, 2019)Introduksjon: Streptococcus agalactiae (gruppe B streptokokker, GBS) er mest kjent for å være årsak til neonatal sepsis. I de senere år har det blitt rapportert en signifikant økning i antall voksne med GBS sykdom fra flere ... -
Comparative genomics to delineate pathogenic potential in Non-O157 Shiga toxin-producing Escherichia coli (STEC) from patients with and without haemolytic uremic syndrome (HUS) in Norway
Haugum, Kjersti; Johansen, Jostein; Gabrielsen, Christina; Brandal, Lin Thorstensen; Bergh, Kåre; Ussery, David Wayne; Drabløs, Finn; Afset, Jan Egil (Journal article; Peer reviewed, 2014)Shiga toxin-producing Escherichia coli (STEC) cause infections in humans ranging from asymptomatic carriage to bloody diarrhoea and haemolytic uremic syndrome (HUS). Here we present whole genome comparison of Norwegian ... -
Comparative Transcriptome Profiling Reveals a Potential Role of Type VI Secretion System and Fimbriae in Virulence of Non-O157 Shiga Toxin-Producing Escherichia coli
Ås, Christina Gabrielsen; Drabløs, Finn; Haugum, Kjersti; Afset, Jan Egil (Journal article; Peer reviewed, 2018)Shiga toxin-producing Escherichia coli (STEC) cause both sporadic infections and outbreaks of enteric disease in humans, with symptoms ranging from asymptomatic carriage to severe disease like haemolytic uremic syndrome ... -
Comparison of iron acquisition mechanisms and growth characteristics of Escherichia coli from bloodstream infection in patients with low and normal iron status
Bista Thapa, Anima (Master thesis, 2019)Sepsis is a systemic inflammatory response to infection which is one of the major public health issues with significant mortality and morbidity. Bloodstream infections are infectious diseases characterised by the presence ... -
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
Degenhardt, Frauke; Ellinghaus, David; Juzenas, Simonas; Lerga-Jaso, Jon; Wendorff, Mareike; Maya-Miles, Douglas; Uellendahl-Werth, Florian; ElAbd, Hesham; Lenning, Ole Bernt; Myhre, Ronny; Vadla, May Sissel; Holten, Aleksander Rygh; Kildal, Anders Benjamin; Lind, Andreas; Dyrhol-Riise, Anne Ma; Hoff, Dag Arne Lihaug; Müller, Fredrik; Solligård, Erik; Holter, Jan Cato; Afset, Jan Egil; Damås, Jan Kristian; Bergan, Jonas; Risnes, Kari; Muller, Karl Erik; Tonby, Kristian; Heggelund, Lars; Gustad, Lise Tuset; Grimsrud, Marit Mæhle; Dudman, Susanne Gjeruldsen; Folseraas, Trine; Skogen, Vegard; Hov, Johannes Espolin Roksund; Karlsen, Tom Hemming; Rühlemann, Malte C.; Arora, Jatin; Özer, Onur; Wacker, Eike Matthias; Wienbrandt, Lars; Ortiz, Aron Blandino; de Salazar, Adolfo; Chercoles, Adolfo Garrido; Palom, Adriana; Ruiz, Agustin; Garzia-Fernandez, Alba-Estela; Blanco-Grau, Albert; Mantovani, Alberto; Zanella, Alberto; Mayer, Alena; Bandera, Alessandra; Franke, Andre (Peer reviewed; Journal article, 2022)Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a deeper analysis of the host genetic contribution to severe COVID-19 is important to improve our understanding of underlying disease ... -
Elements in Staphylococcus aureus associated with endocarditis
Vadet, Nora Moen; ; Ringheim, Åsta Hereid (Master thesis, 2023)Abstrakt Bakgrunn: Infeksiøs endokarditt (IE) er en fryktet infeksjon med høy mortalitet, og et varierende klinisk bilde som gjør diagnostikken utfordrende. Staphylococcus aureus er den vanligste forårsakende mikroben i ... -
Elements in Staphylococcus aureus associated with endocarditis
Vadet, Nora Moen; Ringheim, Åsta Hereid (Master thesis, 2023)Bakgrunn: Infeksiøs endokarditt (IE) er en fryktet infeksjon med høy mortalitet, og et varierende klinisk bilde som gjør diagnostikken utfordrende. Staphylococcus aureus er den vanligste forårsakende mikroben i industriland. ... -
Elucidating the gene encoding the R3 surface protein in Streptococcus agalactiae
Basson, Adelle (Master thesis, 2020)Introduction: S. agalactiae, Lancefield’s group B Streptococcus (GBS), occurs as part of the normal microbial flora of the gastrointestinal and genital tract and can cause critical invasive disease in neonates, including ... -
Elucidating the role of early infections in the etiology of cerebral palsy and other neurodevelopmental disorders
Mynarek, Maren (Doctoral theses at NTNU;2022:381, Doctoral thesis, 2022) -
Epidemiological and clinical characteristics of immunocompromised patients infected with Pneumocystis jirovecii in a twelve-year retrospective study from Norway
Grønseth, Stine; Rogne, Tormod; Hannula, Raisa; Åsvold, Bjørn Olav; Afset, Jan Egil; Damås, Jan Kristian (Journal article; Peer reviewed, 2021) -
Establishing a real-time PCR method for analysis of stx2 expression
Rasmussen, Tilde Harridsleff (Master thesis, 2013)STEC (Shiga toxin-producing E.coli) are important human pathogens, which can potentially cause hemolytic uremic syndrome (HUS). An important predictor of serious disease is the production of the variant Shiga toxin 2 (Stx2). ... -
Etablering av multipleks PCR-analyse for deteksjon av Campylobacter species i avføringsprøver fra pasienter med diaré
Bjørnstad, Eline; Bruvik, Linn (Bachelor thesis, 2022)Campylobacter jejuni og Campylobacter coli er en av de hyppigste årsakene til gastroenteritt hos pasienter med akutt diaré. Det er totalt 11 ulike Campylobacter species som er registrert som tarmpatogene, og det var derfor ... -
Evaluation of Real-Time PCR for rapid phenotypic susceptibility testing of Escherichia coli to gentamicin
Rigstad, Synnøve Nordsteien (Master thesis, 2021)Slappe strategier for infeksjonskontroll og høyt forbruk av antimikrobielle stoffer i noen land gir god grobunn for resistente bakterier, og med en svært sammenkoblet verden kan mikrober spre seg fort. Blodstrømsinfeksjoner ... -
Evaluering av MBT STAR-Carba for deteksjon av karbapenemaseproduserende bakterier ved hjelp av MALDI-TOF MS
Wiik, Kristine; Herstad Sørensen, Tonje (Bachelor thesis, 2022)Antibiotikaresistens i form av karbapenemaseproduksjon i Gram-negative bakterier er en økende helseutfordring på verdensbasis. Plasmidmedierte karbapenemasegener gir økt spredningspotensiale, og spres raskt til og mellom ... -
Fæcesparasittologi. Strategimøte nr 28, 2014
Lier, Tore; Afset, Jan Egil; Merckoll, pact*; Ranheim, Trond Egil; Sandven, Per; Steinbakk, Martin (Eksterne kvalitetsvurderinger i bakteriologi, mykologi og parasitt, Research report, 2015)