Blar i NTNU Open på forfatter "Irla, Marta Katarzyna"
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Characterization of D-arabitol as newly discovered carbon source of Bacillus methanolicus
Lopez, Marina Gil; Irla, Marta Katarzyna; Fernandes de Brito, Luciana; Wendisch, Volker F. (Journal article; Peer reviewed, 2019)Bacillus methanolicus is a Gram-positive, thermophilic, methanol-utilizing bacterium. As a facultative methylotroph, B. methanolicus is also known to utilize D-mannitol, D-glucose and, as recently discovered, sugar alcohol ... -
Construction and characterization of broad-host-range reporter plasmid suitable for on-line analysis of bacterial host responses related to recombinant protein production
Gawin, Agnieszka; Peebo, Karl; Sebastian, Hans; Ertesvåg, Helga; Irla, Marta Katarzyna; Neubauer, Peter; Brautaset, Trygve (Journal article; Peer reviewed, 2019)Background Bacteria are widely used as hosts for recombinant protein production due to their rapid growth, simple media requirement and ability to produce high yields of correctly folded proteins. Overproduction of ... -
Corrigendum: Genome-Based Genetic Tool Development for Bacillus methanolicus: Theta- and Rolling Circle-Replicating Plasmids for Inducible Gene Expression and Application to Methanol-Based Cadaverine Production
Irla, Marta Katarzyna; Heggeset, Tonje Marita Bjerkan; Nærdal, Ingemar; Paul, Lidia; Haugen, Tone; Le, Simone Balzer; Brautaset, Trygve; Wendisch, Volker F. (Journal article; Peer reviewed, 2019) -
Detailed transcriptome analysis of the plant growth promoting Paenibacillus riograndensis SBR5 by using RNA-seq technology
Brito, Luciana Fernandes; Irla, Marta Katarzyna; Kalinowski, Jörn; Wendisch, Volker F. (Journal article; Peer reviewed, 2017)Background The plant growth promoting rhizobacterium Paenibacillus riograndensis SBR5 is a promising candidate to serve as crop inoculant. Despite its potential in providing environmental and economic benefits, the species ... -
Developing a riboswitch-mediated regulatory system for metabolic flux control in thermophilic bacillus methanolicus
Irla, Marta Katarzyna; Hakvåg, Sigrid; Brautaset, Trygve (Journal article; Peer reviewed, 2021) -
Development of a markerless tool for targeted deletion of chromosomal genes in the thermotolerant and methylotrophic bacterium Bacillus methanolicus
Langlo, Jesper (Master thesis, 2020)Bakterien Bacillus methanolicus (B. methanolicus) utgjør en svært interessant kandidat innen industriell bioteknologi, i hovedsak grunnet dens termofile og metylotrofiske egenskaper, og for at den kan produsere høy-verdi ... -
Establishing 3-hydroxypropionic acid production in Bacillus methanolicus MGA3 by heterologous expression of malonyl coenzyme A reductase and malonic semialdehyde reductase
Jacobsen, Robert Torsvik (Master thesis, 2022)3-Hydroxypropionsyre regnes å være en av de mest sentrale biobaserte kjemikaliene som kan produseres fra fornybare karbohydrater. Syren brukes som en forløper for flere ulike kjemiske forbindelser i produksjon av forbruksvarer. ... -
Establishment of a functional system for recombinant production of secreted proteins at 50 °C in the thermophilic Bacillus methanolicus
Irla, Marta Katarzyna; Drejer, Eivind Bøe; Brautaset, Trygve; Hakvåg, Sigrid (Peer reviewed; Journal article, 2020)Background The suitability of bacteria as microbial cell factories is dependent on several factors such as price of feedstock, product range, production yield and ease of downstream processing. The facultative methylotroph ... -
Evaluation of Heterologous Biosynthetic Pathways for Methanol-Based 5-Aminovalerate Production by Thermophilic Bacillus methanolicus
Brito, Luciana Fernandes; Irla, Marta Katarzyna; Balzer, Simone; Nærdal, Ingemar; Brautaset, Trygve (Journal article; Peer reviewed, 2021)The use of methanol as carbon source for biotechnological processes has recently attracted great interest due to its relatively low price, high abundance, high purity, and the fact that it is a non-food raw material. In ... -
Exploring the Potential of Bacillus methanolicus for Expansion of C1 Substrate Range
Lund, Simen Jervell (Master thesis, 2023)Bruken av den metylotrofe og termofile bakterien B. methanolicus MGA3 som en vert for syntetisk metanotrofi representerer en tiltalende mulighet til å bruke billig metangass som karbonkilde i bioteknologisk produksjon. ... -
Genetic Tools and Techniques for Recombinant Expression in Thermophilic Bacillaceae
Drejer, Eivind Bøe; Hakvåg, Sigrid; Irla, Marta Katarzyna; Brautaset, Trygve (Journal article; Peer reviewed, 2018)Although Escherichia coli and Bacillus subtilis are the most prominent bacterial hosts for recombinant protein production by far, additional species are being explored as alternatives for production of difficult-to-express ... -
Metabolic engineering of B. methanolicus for production of 3-hydroxypropionic acid
Cigriejus, Paulius (Master thesis, 2020)Bacillus methanolicus er en Gram-positiv, stavformet, metylotrof og termofil bakterie som kan vokse på metanol som eneste karbonkilde, noe som gjør den til en attraktiv vertsorganisme for mikrobiell produksjon av diverse ... -
Metabolic engineering of industrially relevant strains for the production of riboflavin from sustainable feedstocks
Klein, Vivien Jessica (Doctoral theses at NTNU;2024:95, Doctoral thesis, 2024)There is an increasing demand for agricultural land and other resources necessary to feed an expanding world population. This has led to a growing interest in using sustainable feedstocks to produce value-added compounds ... -
Metabolic Engineering of thermophilic Bacillus methanolicus for riboflavin overproduction from methanol
Klein, Vivien Jessica; Brito, Luciana Fernandes; Perez-Garcia, Fernando; Brautaset, Trygve; Irla, Marta Katarzyna (Peer reviewed; Journal article, 2023)The growing need of next generation feedstocks for biotechnology spurs an intensification of research on the utilization of methanol as carbon and energy source for biotechnological processes. In this paper, we introduced ... -
Methane monooxygenases: central enzymes in methanotrophy with promising biotechnological applications
Khider, May Laura Kilano; Brautaset, Trygve; Irla, Marta Katarzyna (Peer reviewed; Journal article, 2021)Worldwide, the use of methane is limited to generating power, electricity, heating, and for production of chemicals. We believe this valuable gas can be employed more widely. Here we review the possibility of using methane ... -
Methanol-based acetoin production by genetically engineered Bacillus methanolicus
Drejer, Eivind Bøe; Chan, Dennis; Haupka, Carsten; Wendisch, Volker F.; Brautaset, Trygve; Irla, Marta Katarzyna (Journal article; Peer reviewed, 2019)Methanol is an attractive alternative non-food feedstock for industrial fermentations that can be used instead of sugar-based raw materials. Here, the thermophilic and methylotrophic bacterium Bacillus methanolicus MGA3 ... -
Unravelling Formaldehyde Metabolism in Bacteria: Road towards Synthetic Methylotrophy
Klein, Vivien Jessica; Irla, Marta Katarzyna; Gil Lopez, Marina; Brautaset, Trygve; Fernandes de Brito, Luciana (Peer reviewed; Journal article, 2022)Formaldehyde metabolism is prevalent in all organisms, where the accumulation of formaldehyde can be prevented through the activity of dissimilation pathways. Furthermore, formaldehyde assimilatory pathways play a fundamental ...