Browsing NTNU Open by Author "Guragain, Prashanna"
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Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein
Tesfahun, Almaz Nigatu; Alexeeva, Marina; Tomkuvienė, Miglė; Arshad, Aysha; Guragain, Prashanna; Klungland, Arne; Klimašauskas, Saulius; Ruoff, Peter; Bjelland, Svein (Peer reviewed; Journal article, 2021)DNA polymerase III mis-insertion may, where not corrected by its 3′→ 5′ exonuclease or the mismatch repair (MMR) function, result in all possible non-cognate base pairs in DNA generating base substitutions. The most ... -
Excision of the doubly methylated base N4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins
Alexeeva, Marina; Guragain, Prashanna; Tesfahun, Almaz Nigatu; Tomkuvienė, Miglė; Arshad, Aysha; Gerasimaitė, Rūta; Rukšėnaitė, Audronė; Urbanavičiūtė, Giedrė; Bjørås, Magnar; Lærdahl, Jon Kristen; Klungland, Arne; Klimašauskas, Saulius; Bjelland, Svein (Journal article; Peer reviewed, 2018)Cytosine (C) in DNA is often modified to 5-methylcytosine (m5C) to execute important cellular functions. Despite the significance of m5C for epigenetic regulation in mammals, damage to m5C has received little attention. ... -
Expression profiles and initial RNAi experiments with tyrosine hydroxylase and tryptophan 2,3-dioxygenase encoding genes in the salmon louse (Lepeophtheirus salmonis)
Opsahl, Narve Nikolai (Master thesis, 2021)Lakselus er en ektoparasittisk copepode på laksefisk. Den fører til betydelige økonomiske tap i oppdrettsindustrien, samtidig som den representerer en velferdstrussel for oppdrettslaksefisker og en mulig trussel mot ville ... -
IIb-RAD-sequencing coupled with random forest classification indicates regional population structuring and sex-specific differentiation in salmon lice (Lepeophtheirus salmonis)
Guragain, Prashanna; Båtnes, Anna Solvang; Zobolas, John; Olsen, Yngvar; Bones, Atle M.; Winge, Per (Peer reviewed; Journal article, 2022)The aquaculture industry has been dealing with salmon lice problems forming serious threats to salmonid farming. Several treatment approaches have been used to control the parasite. Treatment effectiveness must be optimized, ... -
Phenylalanine Hydroxylase RNAi Knockdown Negatively Affects Larval Development, Molting and Swimming Performance of Salmon Lice
Guragain, Prashanna; Sporsheim, Bjørnar; Skjesol, Astrid; Båtnes, Anna Solvang; Olsen, Yngvar; Bones, Atle M.; Winge, Per (Peer reviewed; Journal article, 2020)Phenylalanine hydroxylase (PAH) is a crucial enzyme involved in tyrosine biosynthesis, having roles in neurological and physiological processes. The purpose of PAH has received little attention in crustaceans despite ... -
Population analysis and structure and RNA interference to understand salmon lice biology and a review of the principles of controlling infestation in aquaculture facilities
Guragain, Prashanna (Doctoral theses at NTNU;2022:232, Doctoral thesis, 2022)The arthropod salmon louse (Lepeophtheirus salmonis) is a significant hazard to aquaculture and to the wild Atlantic salmon. In a monoculture environment, very high host densities may result in rapid reproduction and in ... -
Principles and Methods of Counteracting Harmful Salmon–Arthropod Interactions in Salmon Farming: Addressing Possibilities, Limitations, and Future Options
Guragain, Prashanna; Tkachov, Max; Båtnes, Anna Solvang; Olsen, Yngvar; Winge, Per; Bones, Atle M. (Peer reviewed; Journal article, 2021)The arthropod salmon louse (Lepeophtheirus salmonis) is a major threat to Atlantic salmon aquaculture and wild salmonids. Essentially like in monoculture, very high concentrations of susceptible hosts may result in high ... -
The effect of glucosinolates in the salmon louse (Lepeophtheirus salmonis) larvae and on their gene expression
Mathisen, Ellen Karine Refne Mathisen (Master thesis, 2022)Lakselusen (Lepeophtheirus salmonis) er en ektoparasitt som infiserer ulike laksearter som laks (Salmo salar), sjøørret (Salmo trutta), røye (Salvelinus alpinus) og regnbueørret (Oncorhynchus mykiss). Lakselus utgjør en ...