Blar i NTNU Open på forfatter "Eftedal, Ingrid"
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A Comparison of Two Methods, Urine Specific Gravity and Bioelectrical Impedance, to Measure Short-Time Effects of Underwater Work on Saturation Divers´ Hydration Status
Landsverk, Halvor Dagssøn (Master thesis, 2022)Metningsdykking er en veletablert metode som tillater dykkere å jobbe under vann over lengre perioder. En av utfordringene dykkerne står overfor under metningsdykking er å holde seg hydrerte. Det finnes flere metoder som ... -
A single simulated heliox dive modifies endothelial function in the vascular wall of ApoE knockout male rats more than females
Ardestani, Simin; Matchkov, Vladimir V.; Eftedal, Ingrid; Pedersen, Michael (Journal article; Peer reviewed, 2019)Introduction: The number of divers is rising every year, including an increasing number of aging persons with impaired endothelial function and concomitant atherosclerosis. While diving is an independent modulator of ... -
Acute and potentially persistent effects of scuba diving on the blood transcriptome of experienced divers
Eftedal, Ingrid; Ljubkovic, Marko; Flatberg, Arnar; Jørgensen, Arve; Brubakk, Alf O; Dujic, Zeljko (Journal article; Peer reviewed, 2013)During scuba diving, the circulatory system is stressed by an elevated partial pressure of oxygen while the diver is submerged and by decompression-induced gas bubbles on ascent to the surface. This diving-induced stress ... -
Acute effects on the human peripheral blood transcriptome of decompression sickness secondary to scuba diving
Magri, Kurt; Eftedal, Ingrid; Magri, Vanessa Petroni; Matity, Lyubisa; Muscat, Stephen; Pace, Nikolai Paul (Peer reviewed; Journal article, 2021)Decompression sickness (DCS) develops due to inert gas bubble formation in bodily tissues and in the circulation, leading to a wide range of potentially serious clinical manifestations. Its pathophysiology remains incompletely ... -
Age, weight and decompression sickness in rats
Buzzacott, Peter; Theron, Michael; Mazur, Aleksandra; Wang, Qiong; Lambrechts, Kate; Eftedal, Ingrid; Berenji Ardestani, Simin; Guerrero, Francois (Journal article; Peer reviewed, 2016)Objective: The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats. Methods: Following compression-decompression, male rats aged 11 weeks were ... -
The Assessment of Daily Energy Expenditure of Commercial Saturation Divers using Doubly Labelled Water
Deb, Sanjoy Kumar; Dolan, Eimear; Hambley, Catherine; Zariwala, Mohammed Gulrez; Eftedal, Ingrid (Peer reviewed; Journal article, 2021)Commercial saturation divers are exposed to unique environmental conditions and are required to conduct work activity underwater. Consequently, divers’ physiological status is shown to be perturbed and therefore, appropriate ... -
Blood gene expression and vascular function biomarkers in professional saturation diving
Kiboub, Fatima Zohra; Møllerløkken, Andreas; Hjelde, Astrid; Flatberg, Arnar; Loennechen, Øyvind; Eftedal, Ingrid (Journal article; Peer reviewed, 2018)Saturation diving is an established way to conduct subsea operations with human intervention. While working, the divers must acclimatize to the hyperbaric environments. In this study, genome-wide gene expression and selected ... -
Commercial divers’ subjective evaluation of saturation
Imbert, Jean Pierre; Balestra, Costantino; Kiboub, Fatima Zohra; Loennechen, Øyvind; Eftedal, Ingrid (Journal article; Peer reviewed, 2018)Commercial saturation diving involves divers living and working in an enclosed atmosphere with elevated partial pressure of oxygen (ppO2) for weeks. The divers must acclimatize to these conditions during compression, and ... -
Commercial Saturation Divers: Blood biochemistry and perceptions of acclimatization to oxygen and oxidative stress; in saturation and back to surface
Kiboub, Fatima Zohra (Doctoral theses at NTNU;2018:322, Doctoral thesis, 2018)Norsk sammendrag – Summary in Norwegian Profesjonelle metningsdykkere har arbeidet olje- og gassindustrien i Nordsjøen siden 1960-tallet. Disse dykkerne jobber under krevende forhold; de utfører arbeidsoppgaver som kan ... -
Continuous hemodynamic monitoring in an intact rat model of simulated diving
Gaustad, Svein Erik; Kondratyev, Timofey; Eftedal, Ingrid; Tveita, Torkjel (Journal article; Peer reviewed, 2020)Cardiovascular risk is elevated in divers, but detailed information of cardiac function during diving is missing. The aim of this study was to apply an intact rat model with continuous monitoring of cardiac left ventricular ... -
CYP2C19 – genvariant CYP2C19*17 og rask omsetting av legemidler
Syversen, Corina (Master thesis, 2011)Mutasjoner i genene som koder for CYP-enzymene med klinisk betydning, påvirker aktiviteten til enzymet. Doseringen av legemidler må tilpasses for å oppnå den ønskede responsen på legemiddelbehandlingen. Genet CYP2C19 koder ... -
Eccentric exercise 48 h prior to simulated diving has no effect on vascular bubble formation in rats
Jørgensen, Arve; Ekdahl, Anna Madeleine; Havnes, Marianne Bjordal; Eftedal, Ingrid (Journal article; Peer reviewed, 2014)PURPOSE: Decompression sickness (DCS) caused by vascular bubble formation is a major risk when diving. Prior studies have shown that physical exercise has a significant impact in both reducing and increasing bubble formation. ... -
Effects of cold decompression on hemodynamic function and DCS risk in a dry diving rat model
Gaustad, Svein Erik; Kondratyev, Timofey; Eftedal, Ingrid; Tveita, Torkjel (Peer reviewed; Journal article, 2021)Background: Diving in cold water is thought to increase the risk of decompression sickness (DCS), especially if the diver is cold during decompression. In this study, we investigated hemodynamic function and DCS risk in ... -
Effects of hyperbaric oxygen preconditioning on cardiac stress markers after simulated diving.
Jørgensen, Arve; Foster, Philip P; Brubakk, Alf O; Eftedal, Ingrid (Journal article; Peer reviewed, 2013)Hyperbaric oxygen preconditioning (HBO-PC) can protect the heart from injury during subsequent ischemia. The presence of high loads of venous gas emboli (VGE) induced by a rapid ambient pressure reduction on ascent from ... -
Endothelial dysfunction in small arteries and early signs of atherosclerosis in ApoE knockout rats
Berenji Ardestani, Simin; Eftedal, Ingrid; Pedersen, Michael; Jeppesen, Per Bendix; Nørregaard, Rikke; Matchkov, Vladimir V. (Peer reviewed; Journal article, 2020)Endothelial dysfunction is recognized as a major contributor to atherosclerosis and has been suggested to be evident far before plaque formation. Endothelial dysfunction in small resistance arteries has been suggested to ... -
Evaluating PAI-1 as a biomarker for stress in diving: human serum total PAI-1 is unaltered after 2 h dry exposures to 280 kPa hyperbaric air
Eftedal, Ingrid; Fredriksen, Hallvard Aglen; Hjelde, Astrid; Møllerløkken, Andreas (Journal article; Peer reviewed, 2015)Plasminogen activator inhibitor (PAI-1) is induced in the vasculature and secreted into the vascular lumen in response to inflammation and oxidative stress. We have previously reported a fivefold increase in plasma PAI-1 ... -
Evolution of the plasma proteome of divers before and after a single SCUBA dive
Lautridou, Jacky; Pichereau, Vianney; Artigaud, Sébastien; Bernay, Benoit; Barak, Otto; Hoiland, Ryan; Lovering, Andrew T; Eftedal, Ingrid; Dujic, Zeljko; Guerrero, François (Journal article; Peer reviewed, 2017)Purpose: Decompression sickness (DCS) is a poorly understood and complex systemic disease caused by inadequate desaturation following a reduction of ambient pressure. A previous proteomic study of ours showed that DCS ... -
Extensive simulated diving aggravates endothelial dysfunction in male pro-atherosclerotic ApoE knockout rats
Berenji Ardestani, Simin; Matchkov, Vladimir V.; Hansen, Kasper; Jespersen, Nichlas Rise; Pedersen, Michael; Eftedal, Ingrid (Peer reviewed; Journal article, 2020)Introduction: The average age of the diving population is rising, and the risk of atherosclerosis and cardiovascular disease in divers are accordingly increasing. It is an open question whether this risk is altered by ... -
Functional profiling reveals altered metabolic activity in divers’ oral microbiota during commercial heliox saturation diving
Monnoyer, Roxane; Eftedal, Ingrid; Hjelde, Astrid; Deb, Sanjoy Kumar; Haugum, Kjersti; Lautridou, Jacky (Peer reviewed; Journal article, 2021)Background: The extreme environment in saturation diving affects all life forms, including the bacteria that reside on human skin and mucosa. The oral cavity alone is home to hundreds of different bacteria. In this study, ... -
Heliox Saturation Diving to 500kPa. Effects of Saturation Diving on Oxidative Stress in a Rat Model
Lie, Ingunn (Master thesis, 2014)Formation of vascular gas bubbles following decompression has for a long time been considered to be the main initiator of decompression related illness. However, the presence of silent bubbles may suggest another underlying ...