Blar i NTNU Open på forfatter "Klepstad, Pål"

Viser treff 61-80 av 83

    • Short-term Effects of Endotracheal Suctioning in Post-Cardiac Arrest Patients 

      Eggen, Idunn Banschbach; Brønstad, Gunhild (Master thesis, 2020)
      Introduksjon: Endotrakeal suging er en intensivprosedyre som er nødvendig for å opprettholde åpne luftveier, men som ofte kan føre til uheldige fysiologiske effekter. Vi studerte insidensen av og risikofaktorer for slike ...

    • Short-term effects of endotracheal suctioning in post-cardiac arrest patients: A prospective observational cohort study 

      Eggen, Idunn Banschbach; Brønstad, Gunhild; Langeland, Halvor; Klepstad, Pål; Nordseth, Trond (Peer reviewed; Journal article, 2022)
      Background Endotracheal suctioning (ETS) is required in critically ill patients but may lead to adverse physiologic effects. The aim of this study was to investigate risk factors associated with adverse respiratory and ...

    • The short-term impact of methylprednisolone on patient-reported sleep in patients with advanced cancer in a randomized, placebo-controlled, double-blind trial 

      Jakobsen, Gunnhild; Engstrøm, Morten; Hjermstad, Marianne Jensen; Rosland, Jan Henrik; Aass, Nina Kathrine; Albert, Eva; Kaasa, Stein; Fayers, Peter; Klepstad, Pål; Paulsen, Ørnulf (Peer reviewed; Journal article, 2020)
      Purpose: Although corticosteroids are frequently used in patients with advanced cancer, few studies have examined the impact of these drugs on patient-reported sleep. We aimed to examine the short-term impact of ...

    • Sleep in patients with advanced cancer 

      Jakobsen, Gunnhild (Doctoral theses at NTNU;2019:298, Doctoral thesis, 2019)

    • Sleep quality in hospitalized patients with advanced cancer: an observational study using self-reports of sleep and actigraphy 

      Jakobsen, Gunnhild; Engstrøm, Morten; Thronæs, Morten; Løhre, Erik Torbjørn; Kaasa, Stein; Fayers, Peter; Hjermstad, Marianne Jensen; Klepstad, Pål (Journal article; Peer reviewed, 2019)
      Purpose Although patients with advanced cancer report poor sleep quality, few studies have assessed sleep quality with a combination of subjective and objective measures. We aimed to examine sleep quality in hospitalized ...

    • Sleep quality with WHO Step III opioid use for cancer pain 

      Jakobsen, Gunnhild; Engstrøm, Morten; Fayers, Peter; Hjermstad, Marianne Jensen; Kaasa, Stein; Kloke, Marianne; Sabatowski, Rainer; Klepstad, Pål (Journal article; Peer reviewed, 2018)
      Objective Sleep is often disturbed in patients with advanced cancer. There is limited knowledge about sleep in patients with cancer treated with strong opioids. This study examines sleep quality in patients with advanced ...

    • A survey of preferences for respiratory support in the intensive care unit for patients with acute hypoxaemic respiratory failure 

      Aslam, Tayyba Naz; Klitgaard, Thomas L.; Ahlstedt, Christian A. O.; Andersen, Finn H.; Chew, Michelle S.; Collet, Marie O.; Cronhjort, Maria; Estrup, Stine; Fossum, Ole Kristian; Frisvold, Shirin K.; Gillmann, Hans-Joerg; Granholm, Anders; Gundem, Trine M.; Hauss, Kristin; Hollenberg, Jacob; Condori, Maria E. Huanca; Hastbacka, Johanna; Johnstad, Bror Anders; Keus, Eric; Kjær, Maj-Brit N.; Klepstad, Pål; Krag, Mette; Kvåle, Reidar; Malbrain, Manu L. N. G.; Meyhoff, Christian S.; Morgan, Matt; Møller, Anders; Pfortmueller, Carmen A.; Poulsen, Lone M.; Robertson, Andrew C.; Schefold, Joerg C.; Schjørring, Olav L.; Siegemund, Martin; Sigurdsson, Martin I.; Sjövall, Fredrik; Strand, Kristian; Stueber, Thomas; Szczeklik, Wojciech; Wahlin, Rebecka R.; Wangberg, Helge L.; Wian, Karl-Andre; Wichmann, Sine; Hofsø, Kristin; Møller, Morten H.; Perner, Anders; Rasmussen, Bodil S.; Laake, Jon H. (Peer reviewed; Journal article, 2023)
      Background: When caring for mechanically ventilated adults with acute hypoxaemic respiratory failure (AHRF), clinicians are faced with an uncertain choice between ventilator modes allowing for spontaneous breaths or ...

    • The Association Between Sleep Duration and Delirium in Geriatric Patients 

      Brevik, Kristine Tetlie (Master thesis, 2021)
      Introduksjon: Delirium og dårlig søvn er vanlig blant eldre og kritisk syke pasienter, og er assosiert med alvorlige komplikasjoner. Andelen eldre pasienter øker, også blant intensivpasienter, likevel er det lite forskning ...

    • The need for treatment in a high dependency unit following major abdominal surgery 

      Lefstad, Lars; Rist, Martin (Master thesis, 2015)
      Introduction: Patients undergoing major surgical procedures, such as gastrointestinal cancer surgery, are considered to be at high risk for postoperative complications. Therefore, these patients are routinely monitored in ...

    • The Palliative Radiotherapy and Inflammation Study (PRAIS) - Protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain 11 Medical and Health Sciences 1103 Clinical Sciences 

      Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Abramova, Tatiana Mikhailovna; Baas, Theo; Mørkeset, Siri Tessem; Caraceni, Augusto; Laird, Barry J; Boland, Jason W.; Rossi, Romina; Garcia-Alonso, Elena; Stensheim, Hanne; Loge, Jon Håvard; Hjermstad, Marianne Jensen; Bjerkeset, Ellen; Bye, Asta; Lund, Jo-Åsmund; Solheim, Tora Skeidsvoll; Vagnildhaug, Ola Magne; Brunelli, Cinzia; Damås, Jan Kristian; Mollnes, Tom Eirik; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2018)
      Background Radiation therapy (RT) results in pain relief for about 6 of 10 patients with cancer induced bone pain (CIBP) caused by bone metastases. The high number of non-responders, the long median time from RT to pain ...

    • The rare Arg181Cys mutation in the μ opioid receptor can abolish opioid responses 

      Skorpen, Frank; von Hofacker, Sebastian; Bjørngaard, Mads; Skogholt, Anne Heidi; Dale, Ola; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2016)
      BACKGROUND: Genetic variability contributes to variable clinical response to opioids. This study emerged from the observation of three Norwegian patients who showed no or extraordinary poor response to very high doses of ...

    • The relationship between pro-inflammatory cytokines and pain, appetite and fatigue in patients with advanced cancer 

      Paulsen, Ørnulf; Laird, Barry J; Aass, Nina Kathrine; Lea, Tor Erling; Fayers, Peter; Kaasa, Stein; Klepstad, Pål (Journal article; Peer reviewed, 2017)
      Background Systemic inflammation is associated with reduced quality of life and increased symptoms in patients with advanced cancer. The aims of this study were to examine the relationships between inflammatory biomarkers ...

    • The trauma system and the patient - a national, regional and individual perspective 

      Uleberg, Oddvar (Doctoral theses at NTNU;2019:48, Doctoral thesis, 2019)
      Sammendrag Traumesystemet og pasienten - et nasjonalt, regionalt og individuelt perspektiv Morbiditet og mortalitet som følge av traumatiske skader utgjør på verdensbasis en betydelig helseutfordring både for samfunnet ...

    • Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU) 

      Anthon, Carl Thomas; Pène, Frédéric; Perner, Anders; Azoulay, Elie; Puxty, Kathryn; Van De Louw, Andry; Barratt-Due, Andreas; Chawla, Sanjay; Castro, Pedro; Póvoa, Pedro; Coelho, Luis; Metaxa, Victoria; Kochanek, Matthias; Liebregts, Tobias; Kander, Thomas; Hästbacka, Johanna; Andreasen, Jo Bønding; Péju, Edwige; Nielsen, Lene Bjerregaard; Hvas, Christine Lodberg; Dufranc, Etienne; Canet, Emmanuel; Lundqvist, Linda; Wright, Christopher John; Schmidt, Julien; Uhel, Fabrice; Ait-Oufella, Hafid; Krag, Mette; Cos Badia, Elisabet; Díaz-Lagares, Cándido; Menat, Sophie; Voiriot, Guillaume; Clausen, Niels Erikstrup; Lorentzen, Kristian; Kvåle, Reidar; Hildebrandt, Thomas; Holten, Aleksander Rygh; Strand, Kristian; Tzalavras, Asterios; Bestle, Morten Heiberg; Klepstad, Pål; Fernandez, Sara; Vimpere, Damien; Paulino, Carolina; Graça, Carina; Lueck, Catherina; Juhl, Christian Svendsen; Costa, Carolina; Bådstøløkken, Per Martin; Miranda, Teresa; Lêdo, Lia Susana Aires; Sousa Torres, Joao Carlos; Granholm, Anders; Møller, Morten Hylander; Russell, Lene; Khalil, Ahmed; Yehia, Ahmed; Salem, Haney; Farahat, Hesham; Sudevan, Manu; Biggart, Melissa; Fatima, Nirmeen; Elkhonezy, Mohammed; Bunzel, Anne-Marie; Siegumfeldt, Rine M.; Vestergaard, Stine R.; Pelle, Juliette; Lê, Minh-Pierre; Vigneron, Clara; Bertrix, Morgane; Cirera, Paul; Laghlam, Driss; Bredin, Swann; Marin, Nathalie; Toppenberg, Maria; Benelli, Brice; Seguin, Amélie; Garret, Charlotte; Guillotin, Florian; Blonz, Gauthier; Lascarrou, Jean-Baptiste; Lemarie, Jérémie; Desmedt, Luc; Agbakou, Maïté; Carpentier, Mathieu; Martin, Maëlle; Benkalfate, Naïla; Zambon, Olivier; Decamps, Paul; Wilquin, Pauline L.; Benguerfi, Soraya; Gardner, John; Remor, Natalie; Carr, Sheila; Yang, Gloria; Gernez, Coralie; Thiry, Ingrid; Missri, Louai; Denneborg, Moritz K. G.; Brown, Katherine; Casares, Vanessa; Sivula, Mirka; Lappi, Elina; Pettilä, Leena; Heinonen, Jonna; Saario, Minttu; Mecheri, Manal K.; Elabbadi, Alezandre; Desnos, Cyrielle; Lafarge, Antoine; Mghirbi, Olfa; Sjøbø, Brit Ågot; Christoffersen, Cecilie; Bestle, Frederik H.; Lemos, Claudia; Gonçalves, Cristiana V.; Jacinto, Nuno M. B.; Anselmo, Monica P.; Hoeper, Marius M.; Hoff, Marja; Simões Freire, Pedro M. (Peer reviewed; Journal article, 2023)
      Purpose Thrombocytopenia (platelet count < 150 × 109/L) is common in intensive care unit (ICU) patients and is likely associated with worse outcomes. In this study we present international contemporary data on ...

    • Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study 

      Langeland, Halvor; Bergum, Daniel; Løberg, Magnus; Bjørnstad, Knut; Damås, Jan Kristian; Mollnes, Tom Eirik; Skjaervold, Nils Kristian; Klepstad, Pål (Journal article; Peer reviewed, 2018)
      Background: The post cardiac arrest syndrome (PCAS) is responsible for the majority of in-hospital deaths following cardiac arrest (CA). The major elements of PCAS are anoxic brain injury and circulatory failure. Objective: ...

    • Traumatic brain injury: control of physiological variables, organ failure and complications in the intensive care unit 

      Schirmer-Mikalsen, Kari (Doctoral theses at NTNU;2016:282, Doctoral thesis, 2016)
      SAMMENDRAG Traumatisk hjerneskade: kontroll av fysiologiske variabler, organsvikt og komplikasjoner på intensivavdelingen Traumatisk hjerneskade eller TBI (traumatic brain injury) er hyppig forekommende over hele ...

    • Tromboelastography: variability and relation to conventional coagulation test in non-bleeding intensive care unit patients 

      Halset, Jørgen Holli; Hanssen, Simon Wøhlert; Espinosa, Aurora; Klepstad, Pål (Journal article; Peer reviewed, 2015)
      Background: Intensive care unit (ICU) patients usually have abnormal biochemical and hematological laboratory test results as a consequence of organ dysfunction and underlying disease. Thromboelastography (TEG®) is ...

    • An Update on Prevalence, Assessment, and Risk Factors for Sleep Disturbances in Patients with Advanced Cancer—Implications for Health Care Providers and Clinical Research 

      Jakobsen, Gunnhild; Gjeilo, Kari Hanne; Hjermstad, Marianne Jensen; Klepstad, Pål (Peer reviewed; Journal article, 2022)
      Simple Summary This review focuses on sleep in patients with advanced cancer. Cancer patients experience multiple symptoms and they receive concomitant medications. These are all factors that may affect sleep. In this ...

    • Use of national early warning score for observation for increased risk for clinical deterioration during post-ICU care at a surgical ward 

      Klepstad, Pia Katrin; Nordseth, Trond; Sikora, Normunds; Klepstad, Pål (Journal article; Peer reviewed, 2019)
      Purpose: Patients transferred from an intensive care unit (ICU) to a general ward are at risk for clinical deterioration. The aim of the study was to determine if an increase in National Early Warning Score (NEWS) value ...

    • A Web-Based Communication Tool for Postoperative Follow-up and Pain Assessment at Home After Primary Knee Arthroplasty: Feasibility and Usability Study 

      Rian, Torbjørn; Sand, Kari; Skogvoll, Eirik; Klepstad, Pål; Wik, Tina Strømdal (Peer reviewed; Journal article, 2022)
      Background: We report the use of an electronic tool, Eir (Eir Solutions AS, Norway), for symptom registration at home after knee arthroplasty. This electronic tool was used in a randomized controlled trial (RCT) comparing ...