Blar i NTNU Open på forfatter "Syversen, Unni"
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Should we be concerned about the vitamin A status among Norwegian pregnant women?
Sjilov, Axel (Master thesis, 2020)Norsk sammendrag Bør vi være bekymret for vitamin A status hos norske gravide kvinner? Bakgrunn Vitamin A mangel rammer nesten 20 millioner kvinner på verdensbasis, spesielt i utviklingsland. Mennesker kan ikke produsere ... -
Skeletal Effects of Gastric Hypoacidity in Mice and Humans
Aasarød, Kristin Matre (Doctoral theses at NTNU;2016:301, Doctoral thesis, 2016)Effekt av gastrisk hypoaciditet på bein hos mus og mennesker De siste tiårene har flere epidemiologiske studier vist en assosiasjon mellom bruk av syrehemmende medikamenter (protonpumpehemmere (PPI)) og frakturrisiko. ... -
Skeletal effects of plyometric exercise and metformin in ovariectomized rats
Stunes, Astrid Kamilla; Erben, Reinhold G.; Schüler, Christiane; Eriksen, Erik Fink; Tice, Matthew; Vashishth, Deepak; Syversen, Unni; Mosti, Mats Peder (Journal article; Peer reviewed, 2019)Estrogen deficiency causes bone loss and skeletal muscle dysfunction, and attenuates the musculoskeletal effects of exercise. The anti-diabetic drug metformin has been suggested to promote beneficial skeletal effects. To ... -
Skeletal effects of the saturated 3-thia fatty acid tetradecylthioacetic acid in rats
Stunes, Astrid Kamilla; Westbroek, Irene; Fossmark, Reidar; Berge, Rolf Kristian; Reseland, Janne Elin; Syversen, Unni (Journal article; Peer reviewed, 2011)This study explores the skeletal effects of the peroxisome proliferator activated receptor (PPAR)pan agonist tetradecylthioacetic acid (TTA). Rats, without (Study I) and with ovariectomy (OVX) or sham operation (Study II), ... -
Smoking and other determinants of bone turnover
Jorde, Rolf; Stunes, Astrid Kamilla; Kubiak, Julia Magdalena; Grimnes, Guri; Thorsby, Per Medbøe; Syversen, Unni (Journal article; Peer reviewed, 2019)The balance between bone resorption and formation may be assessed by measurement of bone turnover markers (BTMs), like carboxyl-terminal cross-linked telopeptide of type 1 collagen (CTX-1) and procollagen type 1 amino-terminal ... -
Status of vitamin A among overweight/obese pregnant women: relation to pregnancy complications, birth weight, and metabolic measures
Kinge, Ingvild Tapio (Master thesis, 2022)Den globale prevalensen av vitamin A-mangel og -insuffisiens er høy, og er en av de store årsakene til morbiditet og mortalitet blant barn og gravide, særlig i lavinntektsland. Nyere studier har funnet en sammenheng mellom ... -
Targeting a therapeutically relevant concentration of alendronate for in vitro studies on osteoblasts
Krüger, Tormod Bjartveit; Syversen, Unni; Herlofson, Bente Brokstad; Lian, Aina-Mari; Reseland, Janne Elin (Peer reviewed; Journal article, 2022)Objective Bisphosphonates like alendronate mainly exert their effects on osteoclasts. However, osteoblasts are also affected, but exposed to a much lower concentration in vivo than the osteoclasts. Given that the effects ... -
Technologies for assessment of bone reflecting bone strength and bone mineral density in elderly women: An update
Dhainaut, Alvilde; Hoff, Mari; Syversen, Unni; Haugeberg, Glenn (Peer reviewed; Journal article, 2016)Reduced bone mineral density is a strong risk factor for fracture. The WHO’s definition of osteoporosis is based on bone mineral density measurements assessed by dual x-ray absorptiometry. Several on other techniques than ... -
The effect of an exercise program in pregnancy on vitamin D status among healthy, pregnant Norwegian women: a randomized controlled trial
Gustafsson, Miriam K.; Romundstad, Pål Richard; Stafne, Signe Nilssen; Helvik, Anne-Sofie; Stunes, Astrid Kamilla; Mørkved, Siv; Salvesen, Kjell Å; Thorsby, Per Medbøe; Mosti, Mats Peder; Syversen, Unni (Journal article; Peer reviewed, 2019)Background Vitamin D insufficiency is common in pregnant women worldwide. Regular prenatal exercise is considered beneficial for maternal and fetal health. There is a knowledge gap regarding the impact of prenatal ... -
The Norwegian Capture the Fracture Initiative a stepped wedge cluster randomized 1 controlled trial of a Fracture Liaison Service model of care: The NoFRACT Trial Protocol
Andreasen, Camilla; Solberg, Lene Bergendal; Basso, Trude; Borgen, Tove Tveitan; Dahl, Cecilie; Wisløff, Torbjørn; Hagen, Gunhild; Apalset, Ellen M; Gjertsen, Jan-Erik; Figved, Wender; Hübschle, Lars Michael; Stutzer, Jens-Meinhard; Elvenes, Jan; Joakimsen, Ragnar Martin; Syversen, Unni; Eriksen, Erik Fink; Nordsletten, Lars; Frihagen, Frede Jon; Omsland, Tone Kristin; Bjørnerem, Åshild (Journal article; Peer reviewed, 2018)Importance Fragility fracture is a major health issue because of the accompanying morbidity, mortality, and financial cost. Despite the high cost to society and personal cost to affected individuals, secondary fracture ... -
The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats
Stunes, Astrid Kamilla; Westbroek, Irene; Gustafsson, Björn; Fossmark, Reidar; Waarsing, Jan H; Eriksen, Erik Fink; Petzold, Christiane; Reseland, Janne Elin; Syversen, Unni (Journal article; Peer reviewed, 2011)Background Activation of peroxisome proliferator-activated receptor (PPAR)gamma is associated with bone loss and increased fracture risk, while PPARalpha activation seems to have positive skeletal effects. To further ... -
The prevalence of diabetes mellitus and associated risk factors in the female population of Kavre in rural Nepal
Fossen, Tatyana; Nossen, Julie (Master thesis, 2013)Background: Non-communicable diseases, including diabetes, are the major causes of premature illness and deaths worldwide. The increasing number of people who develop diabetes is due to several modern societal factors, ... -
Validation of FRAX and the impact of self-reported falls among elderly in a general population: the HUNT study, Norway
Hoff, Mari; Meyer, Haakon E; Skurtveit, Svetlana; Langhammer, Arnulf; Søgaard, Anne-Johanne; Syversen, Unni; Dhainaut, Alvilde; Skovlund, Eva; Abrahamsen, B; Schei, Berit (Journal article; Peer reviewed, 2017)Summary Fracture Risk Assessment Tool (FRAX) without bone mineral density (BMD) for hip fracture prediction was validated in a Norwegian population 50–90 years. Fracture risk increased with higher FRAX score, and the ... -
Vitamin D and stress urinary incontinence in pregnancy: a cross-sectional study
Stafne, Signe Nilssen; Mørkved, Siv; Gustafsson, Miriam Katarina; Syversen, Unni; Stunes, Astrid Kamilla; Salvesen, Kjell Å; Johannessen, Hege Hølmo (Peer reviewed; Journal article, 2020)Objective To assess the association between levels of vitamin D and urinary incontinence (UI) in pregnancy. Design A cross‐sectional study. Secondary analysis of a randomised controlled trial. Setting Two university ... -
Vitamin D status among overweight/obese pregnant women: associations with pregnancy complications, birth weight and metabolic parameters
Øvreseth, Anna Hundere (Master thesis, 2022)Sammendrag Bakgrunn: Det er en høy prevalens av vitamin D-mangel globalt, både hos gravide og ikke-gravide. Overvektige har lavere nivå av vitamin D enn slanke. Vitamin D stimulerer kalsiumabsorbsjon i tarmen, og er viktig ... -
Vitamin D Status among Women in a Rural District of Nepal: Determinants and Association with Metabolic Profile—A Population-Based Study
Yogal, Chandra; Borgen, Marianne; Shakya, Sunila; Karmarcharya, Biraj; Koju, Rajendra; Mosti, Mats Peder; Gustafsson, Miriam K.; Åsvold, Bjørn Olav; Schei, Berit; Stunes, Astrid Kamilla; Syversen, Unni (Peer reviewed; Journal article, 2022)Hypovitaminosis D is prevalent worldwide, and especially in South-Asia. According to the Institute of Medicine (IOM), 25(OH)D levels below 30 nmol/L are defined as vitamin D deficiency (VDD) and levels between 30–50 nmol/L ... -
Vitamin D status and healthrelated quality of life in pregnancy - impact of exercise
Gustafsson, Miriam K. (Doctoral theses at NTNU;2018:353, Doctoral thesis, 2018) -
Vitamin K2 modulates vitamin D induced mechanical properties of human 3D bone spheroids in vitro
Schröder, Maria; Riksen, Elisabeth Aurstad; He, Jianying; Skallerud, Bjørn Helge; Møller, Mona Elisabeth; Lian, Aina-Mari; Syversen, Unni; Reseland, Janne Elin (Peer reviewed; Journal article, 2020)Rotational culture promotes primary human osteoblasts (hOBs) to form three-dimensional (3D) multicellular spheroids with bone tissue-like structure without any scaffolding material. Cell-based bone models enable us to ...