Browsing NTNU Open by Author "Kajantie, Eero Olavi"

Now showing items 41-60 of 66

    • Longitudinal changes in plasma hemopexin and alpha-1-microglobulin concentrations in women with and without clinical risk factors for pre-eclampsia 

      Murtoniemi, Katja; Kalapotharakos, Grigorios; Vahlberg, Tero; Raikkonen, Katri; Kajantie, Eero Olavi; Hämäläinen, Esa; Åkerstrom, Bo; Villa, Pia M.; Hansson, Stefan R.; Laivuori, Hannele (Peer reviewed; Journal article, 2019)
      Recent studies have shown increased concentration of fetal hemoglobin (HbF) in pre-eclamptic women. Plasma hemopexin (Hpx) and alpha-1-microglobulin (A1M) are hemoglobin scavenger proteins that protect against toxic effects ...

    • Maternal exposure to childhood maltreatment and mental and behavioral disorders in children 

      Airikka, Aino; Lahti-Pulkkinen, Marius; Tuovinen, Soile; Heinonen, Kati; Lahti, Jari; Girchenko, Polina; Lähdepuro, Anna; Pyhälä, Riikka; Czamara, Darina; Villa, Pia; Laivuori, Hannele; Kajantie, Eero Olavi; Binder, Elisabeth B.; Räikkönen, Katri (Peer reviewed; Journal article, 2022)
      Exposure to maltreatment in childhood is associated with lifelong risk of mental and behavioral disorders. Whether the effects extend to the next generation remains unclear. We examined whether maternal exposure to childhood ...

    • Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium 

      Ronkainen, Justiina; Heiskala, Anni; Vehmeijer, Florianne O.; Lowry, Estelle; Caramaschi, Doretta; Estrada Gutierrez, Guadalupe; Heiss, Jonathan A.; Hummel, Nadine; Keikkala, Elina; Kvist, Tuomas; Kupsco, Allison; Melton, Phillip E.; Pesce, Giancarlo; Soomro, Munawar Hussain; Vives-Usano, Marta; Baïz, Nour; Binder, Elisabeth B.; Czamara, Darina; Guxens, Mònica; Mustaniemi, Sanna; London, Stephanie J.; Rauschert, Sebastian; Vääräsmäki, Marja; Vrijheid, Martine; Ziegler, Anette-G.; Annesi-Maesano, Isabella; Bustamante, Mariona; Huang, Rae-Chi; Hummel, Sandra; Just, Allan C.; Kajantie, Eero Olavi; Lahti, Jari; Lawlor, Debbie A.; Räikkönen, Katri; Jarvelin, Marjo-Riitta; Felix, Janine F.; Sebert, Sylvain (Peer reviewed; Journal article, 2021)
      Altered maternal haemoglobin levels during pregnancy are associated with pre-clinical and clinical conditions affecting the fetus. Evidence from animal models suggests that these associations may be partially explained by ...

    • Maternal mental health and adverse birth outcomes 

      Voit, Falk A.C.; Kajantie, Eero Olavi; Lemola, Sakari; Räikkönen, Katri; Wolke, Dieter; Schnitzlein, Daniel D. (Peer reviewed; Journal article, 2022)
      Recent research in economics emphasizes the role of in utero conditions for the health endowment at birth and in early childhood and for social as well as economic outcomes in later life. This paper analyzes the relation ...

    • Maternal pre-pregnancy overweight and gestational diabetes and dietary intakes among young adult offspring 

      Kaseva, Nina; Vääräsmäki, Marja; Matinolli, Hanna-Maria; Sipola, Marika; Tikanmäki, Marjaana; Kanerva, Noora; Heinonen, Kati; Lano, Aulikki; Wolke, Dieter; Andersson, Sture; Järvelin, Marjo-Riitta; Räikkönen, Katri; Eriksson, Johan G.; Männistö, Satu; Kajantie, Eero Olavi (Peer reviewed; Journal article, 2020)
      Background/Objectives Maternal pre-pregnancy overweight/obesity and gestational diabetes (GDM) are associated with increased fat deposition in adult offspring. The purpose of this study was to identify if maternal ...

    • Mortality among young adults born preterm and early term in 4 Nordic nations 

      Risnes, Kari; Bilsteen, Josephine Funck; Brown, Paul; Pulakka, Anna; Andersen, Anne-Marie Nybo; Opdahl, Signe; Kajantie, Eero Olavi; Sandin, Sven (Peer reviewed; Journal article, 2021)
      Importance Adverse long-term outcomes in individuals born before full gestation are not confined to individuals born at extreme gestational ages. Little is known regarding mortality patterns among individuals born in the ...

    • Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes 

      Pervjakova, Natalia; Moen, Gunn-Helen Øiseth; Borges, Maria-Carolina; Ferreira, Teresa; Cook, James P.; Allard, Catherine; Beaumont, Robin N.; Canouil, Mickaël; Hatem, Gad; Heiskala, Anni; Joensuu, Anni; Karhunen, Ville; Kwak, Soo Heon; Lin, Frederick T J; Liu, Jun; Rifas-Shiman, Sheryl; Tam, Claudia H.; Tam, Wing Hung; Thorleifsson, Gudmar; Andrew, Toby; Auvinen, Juha; Bhowmik, Bishwajit; Bonnefond, Amélie; Delahaye, Fabien; Demirkan, Ayse; Froguel, Philippe; Haller-Kikkatalo, Kadri; Hardardottir, Hildur; Hummel, Sandra; Hussain, Akhtar; Kajantie, Eero Olavi; Keikkala, Elina; Khamis, Amna; Lahti, Jari; Lekva, Tove; Mustaniemi, Sanna; Sommer, Christine; Tagoma, Aili; Tzala, Evangelia; Uibo, Raivo; Vääräsmäki, Marja; Villa, Pia M.; Birkeland, Kåre Inge; Bouchard, Luigi; Duijn, Cornelia M.; Finer, Sarah; Groop, Leif; Hämäläinen, Esa; Hayes, Geoffrey M.; Hitman, Graham A.; Jang, Hak C.; Järvelin, Marjo-Riitta; Jenum, Anne Karen; Laivuori, Hannele; Ma, Ronald C.; Melander, Olle; Oken, Emily; Park, Kyong Soo; Perron, Patrice; Prasad, Rashmi B.; Qvigstad, Elisabeth; Sebert, Sylvain; Stefansson, Kari; Steinthorsdottir, Valgerdur; Tuomi, Tiinamaija; Hivert, Marie-France; Franks, Paul W.; McCarthy, Mark I.; Lindgren, Cecilia M.; Freathy, Rachel M.; Lawlor, Deborah A.; Morris, Andrew P.; Mägi, Reedik (Peer reviewed; Journal article, 2022)
      Gestational diabetes mellitus (GDM) is associated with increased risk of pregnancy complications and adverse perinatal outcomes. GDM often reoccurs and is associated with increased risk of subsequent diagnosis of type 2 ...

    • Non-melancholic depressive symptoms are associated with above average fat mass index in the Helsinki birth cohort study 

      Eriksson, Mia D.; Eriksson, Johan G.; Korhonen, Päivi; Salonen, Minna K.; Mikkola, Tuija M.; Kajantie, Eero Olavi; Wasenius, Niko S.; von Bonsdorff, Mikaela; Kautiainen, Hannu; Laine, Merja K. (Peer reviewed; Journal article, 2022)
      There is an existing link between two of the most common diseases, obesity and depression. These are both of great public health concern, but little is known about the relationships between the subtypes of these conditions. ...

    • Normal Gestational Weight Gain Protects From Large-for-Gestational-Age Birth Among Women With Obesity and Gestational Diabetes 

      Mustaniemi, Sanna; Nikkinen, Hilkka; Bloigu, Aini; Pouta, Anneli; Kaaja, Risto; Eriksson, Johan G.; Laivuori, Hannele; Gissler, Mika; Kajantie, Eero Olavi; Vääräsmäki, Marja (Peer reviewed; Journal article, 2021)
      Background: Pre-pregnancy obesity, excess gestational weight gain (GWG), and gestational diabetes (GDM) increase fetal growth. Our aim was to assess whether normal GWG is associated with lower risk for a large-for-gestational-age ...

    • Optimism in adults born preterm: Systematic review and individual-participant-data metaanalysis 

      Robinson, Rachel K.; Heinonen, Kati; Girchenko, Polina; Lahti-Pulkkinen, Marius; Kajantie, Eero Olavi; Hovi, Petteri; Lano, Aulikki; Andersson, Sture; Eriksson, Johan G.; Wolke, Dieter; Lemola, Sakari; Raikkonen, Katri (Peer reviewed; Journal article, 2021)
      Aim Preterm birth(<37 gestational weeks) is associated with numerous adversities, however, data on positive developmental outcomes remain limited. We examined if preterm and term born(≥37 gestational weeks) adults differ ...

    • Physical activity and associations with health-related quality of life in adults born small for gestational age at term: a prospective cohort study 

      Mehl, Cathrin Vano; Benum, Silje Dahl; Aakvik, Kristina Anna Djupvik; Kongsvold, Atle Austnes; Mork, Paul Jarle; Kajantie, Eero Olavi; Evensen, Kari Anne Indredavik (Peer reviewed; Journal article, 2023)
      Background Adults born small for gestational age (SGA) have increased risk of adverse health outcomes. Physical activity (PA) is a key determinant of health and health-related quality of life (HRQoL). We aimed to ...

    • A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders 

      Suarez, Anna; Lahti, Jari; Lahti-Pulkkinen, Marius; Girchenko, Polina; Czamara, Darina; Arloth, Janine; Malmberg, Anni LK.; Hämäläinen, Esa; Kajantie, Eero Olavi; Laivuori, Hannele; Villa, Pia M.; Reynolds, Rebecca M.; Provençal, Nadine; Binder, Elisabeth B.; Räikkönen, Katri (Peer reviewed; Journal article, 2020)
      Background Maternal depression and anxiety during pregnancy may enhance fetal exposure to glucocorticoids (GCs) and harm neurodevelopment. We tested whether a novel cross-tissue polyepigenetic biomarker indicative of in ...

    • Positive maternal mental health during pregnancy and mental and behavioral disorders in children: A prospective pregnancy cohort study 

      Lähdepuro, Anna; Lahti-Pulkkinen, Marius; Pyhälä, Riikka; Tuovinen, Soile; Lahti, Jari; Heinonen, Kati; Laivuori, Hannele; Villa, Pia M.; Reynolds, Rebecca M.; Kajantie, Eero Olavi; Girchenko, Polina; Räikkönen, Katri (Journal article; Peer reviewed, 2022)

    • A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation 

      Li, Shaobo; Spitz, Natalia; Ghantous, Akram; Abrishamcar, Sarina; Reimann, Brigitte; Marques, Irene; Silver, Matt J.; Aguilar-Lacasaña, Sofía; Kitaba, Negusse; Rezwan, Faisal I.; Röder, Stefan; Sirignano, Lea; Tuhkanen, Johanna; Mancano, Giulia; Sharp, Gemma C.; Metayer, Catherine; Morimoto, Libby; Stein, Dan J.; Zar, Heather J.; Alfano, Rossella; Nawrot, Tim; Wang, Congrong; Kajantie, Eero Olavi; Keikkala, Elina; Mustaniemi, Sanna; Ronkainen, Justiina; Sebert, Sylvain; Silva, Wnurinham; Vääräsmäki, Marja; Jaddoe, Vincent W. V.; Bernstein, Robin M.; Prentice, Andrew M.; Cosin-Tomas, Marta; Dwyer, Terence; Håberg, Siri Eldevik; Herceg, Zdenko; Magnus, Maria Christine; Munthe-Kaas, Monica Cheng; Page, Christian Magnus; Völker, Maja; Gilles, Maria; Send, Tabea; Witt, Stephanie; Zillich, Lea; Gagliardi, Luigi; Richiardi, Lorenzo; Czamara, Darina; Räikkönen, Katri; Chatzi, Lida; Vafeiadi, Marina; Arshad, S. Hasan; Ewart, Susan; Plusquin, Michelle; Felix, Janine F.; Moore, Sophie E.; Vrijheid, Martine; Holloway, John W.; Karmaus, Wilfried; Herberth, Gunda; Zenclussen, Ana; Streit, Fabian; Lahti, Jari; Hüls, Anke; Hoang, Thanh T.; London, Stephanie J.; Wiemels, Joseph L. (Peer reviewed; Journal article, 2024)
      Higher birth order is associated with altered risk of many disease states. Changes in placentation and exposures to in utero growth factors with successive pregnancies may impact later life disease risk via persistent DNA ...

    • Pregnancy outcomes according to the definition of gestational diabetes 

      Koivunen, Sanna; Viljakainen, Matti; Männistö, Tuija; Gissler, Mika; Pouta, Anneli; Kaaja, Risto; Eriksson, Johan G.; Laivuori, Hannele; Kajantie, Eero Olavi; Vääräsmäki, Marja (Peer reviewed; Journal article, 2020)
      Objective To assess the frequency and perinatal outcomes of gestational diabetes mellitus (GDM) defined by the criteria according to the International Association of Diabetes in Pregnancy Study Group (IADPSG) and the ...

    • Preterm birth and the risk of chronic disease multimorbidity in adolescence and early adulthood: A population-based cohort study 

      Heikkilä, Katriina; Pulakka, Anna; Metsälä, Johanna; Alenius, Suvi; Hovi, Petteri; Gissler, Mika; Sandin, Sven; Kajantie, Eero Olavi (Peer reviewed; Journal article, 2021)
      Background People who were born prematurely have high risks of many individual diseases and conditions in the early part of the life course. However, our knowledge of the burden of multiple diseases (multimorbidity) ...

    • Psychiatric disorders in individuals born very preterm / very low-birth weight: An individual participant data (IPD) meta-analysis 

      Anderson, Peter J; de Miranda, Debora Marques; Albuquerque, Maicon Rodrigues; Indredavik, Marit Sæbø; Evensen, Kari Anne Indredavik; Van Lieshout, Ryan; Saigal, Saroj; Taylor, H. Gerry; Raikkonen, Katri; Kajantie, Eero Olavi; Marlow, Neil; Johnson, Samantha; Woodward, Lianne J.; Austin, Nicola; Nosarti, Chiara; Jaekel, Julia; Wolke, Dieter; Cheong, Jeanie LY; Burnett, Alice; Treyvaud, Karli; Lee, Katherine J; Doyle, Lex W (Peer reviewed; Journal article, 2021)
      Background Data on psychiatric disorders in survivors born very preterm (VP; <32 weeks) or very low birthweight (VLBW; <1500 g) are sparse. We compared rates of psychiatric diagnoses between VP/VLBW and term-born, normal ...

    • Record linkage as a vital key player for the COVID-19 syndemic – The call for legal harmonization to overcome research challenges 

      Doetsch, Julia Nadine; Kajantie, Eero Olavi; Dias, Vasco; Indredavik, Marit Sæbø; Devold, Randi Kallar; Teixeira, Raquel; Reittu, Jarkko; Barros, Henrique (Peer reviewed; Journal article, 2023)
      The initial public health response to the COVID-19 pandemic aimed to prevent exponential dissemination and circumvent drastic collapses of healthcare systems [1]. Containment measures and required isolation promoted sedentary ...

    • The relationship between health-related quality of life and melancholic depressive symptoms is modified by brain insulin receptor gene network 

      Selenius, Jannica S.; Silveira, Patricia P.; Salonen, Minna K; Kautiainen, Hannu; von Bonsdorff, Mikaela; Kajantie, Eero Olavi; Lahti, Jari; Eriksson, Johan G.; Wasenius, N. S. (Peer reviewed; Journal article, 2021)
      To investigate whether expression-based polygenic risk scores for the insulin receptor gene network (ePRS-IRs) modifiy the association between type of depressive symptoms and health-related quality of life (HRQoL). This ...

    • Reliability of a novel approach for reference-based cell type estimation in human placental DNA methylation studies 

      Dieckmann, Linda; Cruceanu, Cristiana; Lahti-Pulkkinen, Marius; Lahti, Jari; Kvist, Tuomas; Laivuori, Hannele; Sammallahti, Sara; Villa, Pia M.; Suomalainen-König, Sanna; Rancourt, Rebecca C.; Plagemann, Andreas; Henrich, Wolfgang; Eriksson, Johan G.; Kajantie, Eero Olavi; Entringer, Sonja; Braun, Thorsten; Räikkönen, Katri; Binder, Elisabeth B.; Czamara, Darina (Peer reviewed; Journal article, 2022)
      The placenta is a central organ during early development, influencing trajectories of health and disease. DNA methylation (DNAm) studies of human placenta improve our understanding of how its function relates to disease ...