Blar i NTNU Open på forfatter "Wiseth, Rune"
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Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction
Ueland, Thor; Kleveland, Ola; Michelsen, Annika; Wiseth, Rune; Damås, Jan Kristian; Holven, Kirsten Bjørklund; Aukrust, Pål; Gullestad, Lars; Yndestad, Arne; Halvorsen, Bente (Journal article; Peer reviewed, 2018)Background The IL-6 receptor antagonist tocilizumab has been shown to attenuate the proatherogenic lipoprotein a [Lp(a)] in rheumatoid arthritis. We evaluated if a single dose of tocilizumab reduced Lp(a) in patients with ... -
Serum PCSK9 is modified by interleukin-6 receptor antagonism in patients with hypercholesterolaemia following non-ST-elevation myocardial infarction
Ueland, Thor; Kleveland, Ola; Michelsen, Annika; Wiseth, Rune; Damås, Jan Kristian; Aukrust, Pål; Gullestad, Lars; Halvorsen, Bente; Yndestad, Arne (Journal article; Peer reviewed, 2018)Objective It is unclear if activation of inflammatory pathways regulates proprotein convertase subtilisin-kexin type 9 (PCSK9) levels. Approach We evaluated (1) the temporal course of serum PCSK9 during hospitalisation ... -
Tocilizumab increases citrullinated histone 3 in non-ST segment elevation myocardial infarction
Helseth, Ragnhild; Kleveland, Ola; Ueland, Thor; Wiseth, Rune; Damås, Jan Kristian; Broch, Kaspar; Michelsen, Annika Elisabet; Bendz, Bjørn; Gullestad, Lars; Aukrust, Pål; Seljeflot, Ingebjørg (Peer reviewed; Journal article, 2021)Objective Beyond reducing inflammation and troponin T (TnT) release, the interleukin-6 receptor antagonist tocilizumab reduces neutrophil counts in patients with non-ST segment elevation myocardial infarction (NSTEMI). It ... -
Transthoracic Doppler echocardiography for the detection of coronary artery stenoses and microvascular coronary dysfunction
Holte, Espen (Doctoral theses at NTNU;2017:322, Doctoral thesis, 2017)Bruk av transtorakal ekkokardiografi for påvisning av kransårestenoser og mikrovaskulær kransåresykdom. I den vestlige verden, er kransåresykdom en av de hyppigste årsakene til sykdom og død. Ved symptomer som gir mistanke ... -
Uncertainty quantification and sensitivity analysis for computational FFR estimation in stable coronary artery disease
Fossan, Fredrik Eikeland; Sturdy, Jacob; Muller, Lucas Omar; Strand, Andreas; Bråten, Anders Tjellaug; Jørgensen, Arve; Wiseth, Rune; Hellevik, Leif Rune (Journal article; Peer reviewed, 2018)Purpose The main objectives of this study are to validate a reduced-order model for the estimation of the fractional flow reserve (FFR) index based on blood flow simulations that incorporate clinical imaging and ...