Now showing items 21-24 of 24

    • Simultaneous Detection of Zinc and Its Pathway Metabolites Using MALDI MS Imaging of Prostate Tissue 

      Andersen, Maria Karoline; Krossa, Sebastian; Høiem, Therese Stork; Buchholz, Rebecca; Claes, Britt S.R.; Balluff, Benjamin; Ellis, Shane; Richardsen, Elin; Bertilsson, Helena; Heeren, Ron M.A.; Bathen, Tone Frost; Karst, Uwe; Giskeødegård, Guro F.; Tessem, May-Britt (Journal article; Peer reviewed, 2020)
      Levels of zinc, along with its mechanistically related metabolites citrateand aspartate, are widely reported as reduced in prostate cancer compared to healthytissue and are therefore pointed out as potential cancer biomarkers. ...
    • Spermine and Citrate as Metabolic Biomarkers for Assessing Prostate Cancer Aggressiveness 

      Giskeødegård, Guro F.; Bertilsson, Helena; Selnæs, Kirsten Margrete; Wright, A.J.; Bathen, Tone Frost; Viset, Trond; Halgunset, Jostein; Angelsen, Anders; Gribbestad, Ingrid S; Tessem, May-Britt (Journal article; Peer reviewed, 2013)
      Separating indolent from aggressive prostate cancer is an important clinical challenge for identifying patients eligible for active surveillance, thereby reducing the risk of overtreatment. The purpose of this study was ...
    • The effect of sampling procedures and day-to-day variations in metabolomics studies of biofluids 

      Giskeødegård, Guro F.; Andreassen, Trygve; Bertilsson, Helena; Tessem, May-Britt; Bathen, Tone Frost (Journal article; Peer reviewed, 2019)
      Metabolomics analysis of biofluids is a feasible tool for disease characterization and monitoring due to its minimally invasive nature. To reduce unwanted variation in biobanks and clinical studies, it is important to ...
    • Tissue microstructure is linked to MRI parameters and metabolite levels in prostate cancer 

      Selnæs, Kirsten Margrete; Vettukattil, Muhammad Riyas; Bertilsson, Helena; Wright, Alan J.; Heerschap, Arend; Angelsen, Anders; Tessem, May-Britt; Bathen, Tone Frost (Peer reviewed; Journal article, 2016)
      Introduction: Magnetic resonance imaging (MRI) can portray spatial variations in tumor heterogeneity, architecture, and its microenvironment in a non-destructive way. The objective of this study was to assess the relationship ...