Browsing NTNU Open by Author "Saltvedt, Ingvild"

Now showing items 21-40 of 90

    • The delirium screening tool 4AT in routine clinical practice: prediction of mortality, sensitivity and specificity 

      Evensen, Sigurd; Hylen Ranhoff, Anette; Lydersen, Stian; Saltvedt, Ingvild (Peer reviewed; Journal article, 2021)
      Purpose Delirium is common and associated with poor outcomes, partly due to underdetection. We investigated if the delirium screening tool 4 A’s test (4AT) score predicts 1 year mortality and explored the sensitivity and ...

    • Development and delivery of patient treatment in the Trondheim Hip Fracture Trial. A new geriatric in-hospital pathway for elderly patients with hip fracture 

      Saltvedt, Ingvild; Prestmo, Anders; Einarsen, Elin Kristin; Johnsen, Lars Gunnar; Helbostad, Jorunn L.; Sletvold, Olav (Journal article; Peer reviewed, 2012)
      Background Hip fractures are common among frail elderly persons and often have serious consequences on function, mobility and mortality. Traditional treatment of these patients is performed in orthopedic departments without ...

    • Digital technology to deliver a lifestyle-integrated exercise intervention in young seniors – the PreventIT feasibility randomised controlled trial 

      Taraldsen, Kristin; Mikolaizak, A. Stefanie; Maier, Andrea B.; Mellone, Sabato; Boulton, Elisabeth; Aminian, Kamiar; Becker, Clemens; Chiari, Lorenzo; Follestad, Turid; Gannon, Brenda; Ionescu, Anisoara; Pijnappels, Mirjam; Saltvedt, Ingvild; Schwenk, Michael; Todd, Chris; Yang, Fan Bella; Zacchi, Anna; Van Ancum, Jeanine M.; Vereijken, Beatrix; Helbostad, Jorunn L. (Peer reviewed; Journal article, 2020)
      Background: Behavioral change is the key to alter individuals’ lifestyle from sedentary to active. The aim was to assess the feasibility of delivering a Lifestyle-integrated Functional Exercise programme and evaluate the ...

    • Drug prescription patterns in elderly hip fracture patients at admission and discharge from hospital: A substudy of the Trondheim Hip Fracture Trial - a randomized controlled trial 

      Heltne, Marianne (Master thesis, 2013)
      Background: Hip fractures in the elderly are common, and may have serious consequences. Drug use might be contributing to the falls and subsequent fractures, and might be of significance as an intervention target. The ...

    • Dual Impairment in Cognition and Physical Performance After Stroke: Prevalence, Pathogenesis and Prediction of Function 

      Einstad, Marte Stine (Doctoral theses at NTNU;2022:205, Doctoral thesis, 2022)
      Dual impairment of physical performance and cognition has been reported to increase the risk of dementia, falls, and functional dependency. However, this coexistence of impairments has to a little extent been explored in ...

    • Effect of in-hospital comprehensive geriatric assessment (CGA) in older people with hip fracture. The protocol of the Trondheim Hip Fracture Trial 

      Sletvold, Olav; Helbostad, Jorunn L.; Thingstad, Pernille; Taraldsen, Kristin; Prestmo, Anders; Lamb, SE; Aamodt, Arild; Johnsen, Roar; Magnussen, Jon; Saltvedt, Ingvild (Journal article; Peer reviewed, 2011)
      Background Hip fractures in older people are associated with high morbidity, mortality, disability and reduction in quality of life. Traditionally people with hip fracture are cared for in orthopaedic departments without ...

    • Eksterne henvisninger ved hoftebrudd behandlet ved en ortogeriatrisk avdeling sammenlignet med standard behandlingsmodell 

      Morstøl Valde, Amund (Master thesis, 2020)
      BAKGRUNN: Hoftebruddpasienter er ofte skrøpelige individer preget av høy alder, flere medisinske problemstillinger og de får ofte komplikasjoner i post-operativt fase som ikke er av ortopedisk karakter. De har derfor i ...

    • Environmental factors and risk of delirium in geriatric patients: An observational study 

      Evensen, Sigurd; Saltvedt, Ingvild; Lydersen, Stian; Wyller, Torgeir Bruun; Taraldsen, Kristin; Sletvold, Olav (Journal article; Peer reviewed, 2018)
      Background Patients with delirium have increased risk of death, dementia and institutionalization, and prognosis differs between delirium motor subtypes. A few studies have identified associations between environmental ...

    • Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease 

      Creese, Byron; Vassos, Evangelos; Bergh, Sverre; Athanasiu, Lavinia; Johar, Iskandar; Rongve, Arvid; Medbøen, Ingrid Tøndel; Da Silva, Miguel Vasconcelos; Aakhus, Eivind; Andersen, Fred; Bettella, Francesco; Brækhus, Anne; Djurovic, Srdjan; Paroni, Giulia; Proitsi, Petroula; Saltvedt, Ingvild; Seripa, Davide; Stordal, Eystein; Fladby, Tormod; Aarsland, Dag; Andreassen, Ole Andreas; Ballard, Clive; Selbæk, Geir (Journal article; Peer reviewed, 2019)
      Psychosis (delusions or hallucinations) in Alzheimer’s disease (AD + P) occurs in up to 50% of individuals and is associated with significantly worse clinical outcomes. Atypical antipsychotics, first developed for ...

    • Factors that influence the levels of cerebrospinal fluid biomarkers in memory clinic patients 

      Knapskog, Anne Brita; Eldholm, Rannveig Sakshaug; Brækhus, Anne; Engedal, Knut; Saltvedt, Ingvild (Journal article; Peer reviewed, 2017)
      Background The cerebrospinal fluid (CSF) biomarkers amyloid β (Aβ), phospho tau (P-tau) and total tau (T-tau) are used increasingly to support a clinical diagnosis of Alzheimer’s disease. The diagnostic power of these ...

    • Gait, physical function, and physical activity in three groups of home-dwelling older adults with different severity of cognitive impairment - a cross-sectional study 

      Taraldsen, Kristin; Helbostad, Jorunn L.; Follestad, Turid; Bergh, Sverre; Selbæk, Geir; Saltvedt, Ingvild (Journal article; Peer reviewed, 2021)
      Background The research on associations between gait, physical function, physical activity (PA), and cognitive function is growing. Still, clinical assessments of cognitive function and motor function is often kept separate. ...

    • GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study 

      Rongve, Arvid; Witoelar, Aree; Ruiz, Agustín; Athanasiu, Lavinia; Abdelnour, Carla; Clarimon, Jordi; Heilmann-Heimbach, Stefanie; Hernández, Isabel; Moreno-Grau, Sonia; de Rojas, Itziar; Morenas-Rodríguez, Estrella; Fladby, Tormod; Sando, Sigrid Botne; Bråthen, Geir; Blanc, Frédéric; Bousiges, Olivier; Lemstra, Afina W.; van Steenoven, Inger; Londos, Elisabet; Almdahl, Ina Selseth; Pålhaugen, Lene; Eriksen, Jon Alm; Djurovic, Srdjan; Stordal, Eystein; Saltvedt, Ingvild; Ulstein, Ingun; Bettella, Francesco; Desikan, Rahul S.; Idland, Ane-Victoria; Toft, Mathias; Pihlstrøm, Lasse; Snaedal, Jon; Tárraga, Lluís; Boada, Mercè; Lleó, Alberto; Stefánsson, Hreinn; Stefánsson, Kári; Ramírez, Alfredo; Aarsland, Dag; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2019)
      Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. Here we ...

    • Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease 

      DeMichele-Sweet, Mary Ann A.; Klei, Lambertus; Creese, Byron; Harwood, Janet C.; Weamer, Elise A.; McClain, Lora; Sims, Rebekka; Hernández, Isabel; Moreno-Grau, Sonia; Tárraga, Lluís; Boada, Mercè; Alarcón-Martín, Emilio; Valero, Sergi; Liu, Yushi; Hooli, Basavaraj; Aarsland, Dag; Selbæk, Geir; Bergh, Sverre; Rongve, Arvid; Saltvedt, Ingvild; Skjellegrind, Håvard; Engdahl, Bo Lars; Stordal, Eystein; Andreassen, Ole Andreas; Djurovic, Srdjan; Athanasiu, Lavinia; Seripa, Davide; Borroni, Barbara; Albani, Diego; Forloni, Gianluigi; Mecocci, Patrizia; Seretti, Alessandro; De Ronchi, Diana; Politis, Antonis; Williams, Julie; Mayeux, Richard; Foroud, Tatiana; Ruiz, Agustin; Ballard, Clive; Holmans, Peter; Lopez, Oscar L.; Kamboh, M. Ilyas; Devlin, Bernie; Sweet, Robert A. (Peer reviewed; Journal article, 2021)
      Psychotic symptoms, defined as the occurrence of delusions or hallucinations, are frequent in Alzheimer disease (AD with psychosis, AD + P). AD + P affects ~50% of individuals with AD, identifies a subgroup with poor ...

    • A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease 

      Wightman, Douglas P.; Jansen, Iris E.; Savage, Jeanne E.; Shadrin, Alexey; Bahrami, Shahram; Holland, Dominic; Rongve, Arvid; Børte, Sigrid; Winsvold, Bendik K S; Drange, Ole Kristian; Martinsen, Amy E.; Skogholt, Anne Heidi; Willer, Cristen; Bråthen, Geir; Bosnes, Ingunn; Nielsen, Jonas Bille; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Meisingset, Tore Wergeland; Zhou, Wei; Proitsi, Petroula; Hodges, Angela; Dobson, Richard; Velayudhan, Latha; Sealock, Julia; Davis, Lea K.; Pedersen, Nancy L.; Reynolds, Chandra A.; Karlsson, Ida K.; Magnusson, Sigurdur; Stefansson, Hreinn; Thordardottir, Steinunn; Jónsson, Pálmi V.; Snædal, Jon; Zettergren, Anna; Skoog, Ingmar; Kern, Silke; Waern, Margda; Zetterberg, Henrik; Blennow, Kaj; Stordal, Eystein; Hveem, Kristian; Zwart, John Anker Henrik; Athanasiu, Lavinia; Selnes, Per; Saltvedt, Ingvild; Sando, Sigrid Botne; Ulstein, Ingun; Djurovic, Srdjan; Fladby, Tormod; Aarsland, Dag; Selbæk, Geir; Ripke, Stephan; Stefánsson, Kári; Andreassen, Ole; Posthuma, Danielle (Journal article; Peer reviewed, 2021)
      Late-onset Alzheimer’s disease is a prevalent age-related polygenic disease that accounts for 50–70% of dementia cases. Currently, only a fraction of the genetic variants underlying Alzheimer’s disease have been identified. ...

    • Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers 

      Jansen, Iris E.; van der Lee, Sven J.; Gomez-Fonseca, Duber; de Rojas, Itziar; Dalmasso, Maria Carolina; Grenier-Boley, Benjamin; Athanasiu, Lavinia; Bahrami, Shahram; Bergh, Sverre; Djurovic, Srdjan; Fladby, Tormod; Jarholm, Jonas Alexander; Knapskog, Anne Brita; Pålhaugen, Lene; Saltvedt, Ingvild; Selbæk, Geir; Selnes, Per; Andreassen, Ole; Shadrin, Alexey; Skoog, Ingmar; Soininen, Hilkka; Tsolaki, Magda; Van Broeckhoven, Christine; Van Dongen, Jasper; van Swieten, John C.; Vandenberghe, Rik; Vidal, Jean-Sébastien; Visser, Pieter J.; Vogelgsang, Jonathan; Waern, Margda; Wagner, Michael; Wiltfang, Jens; Wittens, Mandy M.J.; Zetterberg, Henrik; Zulaica, Miren; van Duijn, Cornelia M.; Bjerke, Maria; Engelborghs, Sebastiaan; Jessen, Frank; Teunissen, Charlotte E.; Pastor, Pau; Hiltunen, Mikko; Ingelsson, Martin; Clarimón, Jordi; Sleegers, Kristel; Ruiz, Agustín; Ramirez, Alfredo; Cruchaga, Carlos; Lambert, Jean-Charles; van der Flier, Wiesje M. (Peer reviewed; Journal article, 2022)
      Amyloid-beta 42 (Aβ42) and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF) reflect core features of the pathogenesis of Alzheimer’s disease (AD) more directly than clinical diagnosis. Initiated by the European ...

    • Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk 

      Jansen, Iris E.; Savage, Jeanne E.; Watanabe, Kyoko; Bryois, Julien; Williams, Dylan M.; Steinberg, Stacy; Sealock, Julia; Karlsson, Ida K.; Hägg, Sara; Athanasiu, Lavinia; Voyle, Nicola; Proitsi, Petroula; Witoelar, Aree; Stringer, Sven; Aarsland, Dag; Almdahl, Ina Selseth; Andersen, Fred; Bergh, Sverre; Bettella, Francesco; Björnsson, Sigurbjörn; Brækhus, Anne; Bråthen, Geir; de Leeuw, Christiaan A.; Desikan, Rahul S.; Djurovic, Srdjan; Dumitrescu, Logan; Fladby, Tormod; Hohman, Timothy J.; Jónsson, Pálmi V.; Kiddle, Steven J; Rongve, Arvid; Saltvedt, Ingvild; Sando, Sigrid Botne; Selbæk, Geir; Shoai, Maryam; Skene, Nathan G.; Snædal, Jón G.; Stordal, Eystein; Ulstein, Ingun; Wang, Yunpeng; White, Linda Rosemary; Hardy, John; Hjerling-Leffler, Jens; Sullivan, Patrick; van der Flier, Wiesje M.; Dobson, Richard; Davis, Lea K; Stefánsson, Hreinn; Stefánsson, Kári; Pedersen, Nancy L; Ripke, Stephan; Andreassen, Ole Andreas; Posthuma, Danielle (Journal article; Peer reviewed, 2019)
      Alzheimer’s disease (AD) is highly heritable and recent studies have identified over 20 disease-associated genomic loci. Yet these only explain a small proportion of the genetic variance, indicating that undiscovered loci ...

    • Geriatric assessment with management for older patients with cancer receiving radiotherapy. Protocol of a Norwegian cluster-randomised controlled pilot study 

      Røyset, Inga Marie; Saltvedt, Ingvild; Rostoft, Siri; Grønberg, Bjørn Henning; Kirkevold, Øyvind; Oldervoll, Line Merethe; Bye, Asta; Saltyte Benth, Jurate; Bergh, Sverre; Melby, Line; Halsteinli, Vidar; Døhl, Øystein; Røsstad, Tove Garåsen; Eriksen, Guro Falk; Sollid, May Ingvild Volungholen; Rolfson, Darryl; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2021)
      About 50% of patients with cancer are expected to need radiotherapy (RT), and the majority of these are older. To improve outcomes for older patients with cancer, geriatric assessment (GA) with management (GAM) is highly ...

    • A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease 

      Edwin, Trine Holt; Henjum, Kristi; Nilsson, Lars N. G.; Watne, Leiv; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug; Saltvedt, Ingvild; Halaas, Nathalie Bodd; Selbæk, Geir; Engedal, Knut; Strand, Bjørn Heine; Knapskog, Anne Brita (Peer reviewed; Journal article, 2020)
      Introduction: The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 ...

    • The Human Brain Representation of Odor Identification in Amnestic Mild Cognitive Impairment and Alzheimer's Dementia of Mild Degree 

      Kjelvik, Grete; Evensmoen, Hallvard Røe; Hummel, Thomas; Engedal, Knut; Selbæk, Geir; Saltvedt, Ingvild; Håberg, Asta (Peer reviewed; Journal article, 2020)
      Background: Odor identification (OI) ability is a suggested early biomarker of Alzheimer’s disease. In this study, we investigated brain activity within the brain’s olfactory network associated with OI in patients with ...

    • The Impact of Classification Models, Stroke Subtype, and Vascular Risk Factors on Courses of Poststroke Cognitive Impairment 

      Aam, Stina (Doctoral theses at NTNU;2021:237, Doctoral thesis, 2021)
      Forekomsten av hjerneslag og demens øker eksponentielt med alder. Grunnet økende antall eldre i befolkningen de nærmeste årene vil denne forekomsten øke betydelig. Behandlingen av hjerneslag har bedret seg de senere årene ...