• Rising rural body-mass index is the main driver of the global obesity epidemic in adults 

      Bixby, Honor; Bentham, James; Zhou, Bin; Di Cesare, Mariachiara; Paciorek, Christopher J.; Bennett, James E.; Taddei, Cristina; Stevens, Gretchen A.; Rodriguez-Martinez, Andrea; Carrillo-Larco, Rodrigo M.; Andersen, Lars Bo; Anderssen, Sigmund Alfred; Ekelund, Ulf; Kolle, Elin; Steene-Johannessen, Jostein; Tarp, Jakob; Ariansen, Inger; Biehl, Anna Månsson; Graff-Iversen, Sidsel; Meisfjord, Jørgen Rajan; Bjertness, Espen; Bjertness, Marius Bergsmark; Meyer, Haakon E; Haugsgjerd, Teresa Risan; Tell, Grethe S.; Janszky, Imre; Krokstad, Steinar; Laugsand, Lars Erik; Sen, Abhijit; Vatten, Lars Johan; Mathiesen, Ellisiv B.; Wilsgaard, Tom; Khang, Young-Ho; Soric, Maroje; Gregg, Edward W.; Miranda, J. Jaime; Bhutta, Zulfiqar A.; Savin, Stefan; Sophiea, Marisa K.; Iurilli, Maria L. C.; Solomon, Bethlehem D.; Cowan, Melanie J.; Riley, Leanne M.; Danaei, Goodarz; Bovet, Pascal; Chirita-Emandi, Adela; Hambleton, Ian R; Hayes, Alison J; Ikeda, Nayu; Kengne, Andre P; Laxmaiah, Avula (Journal article; Peer reviewed, 2019)
      Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbanization is one of the most ...
    • Severity of Depression, Anxious Distress and the Risk of Cardiovascular Disease in a Swedish Population-Based Cohort 

      Almas, Aysha; Forsell, Yvonne; Iqbal, Romaina; Janszky, Imre; Möller, Jette (Peer reviewed; Journal article, 2015)
      Background Depression is known to be associated with cardiovascular diseases (CVD). This population-based cohort study aimed to determine the association between depression of varying severity and risk for CVD and to study ...
    • Social relations in late adolescence and incident coronary heart disease: a 38-year follow-up of the Swedish 1969-1970 Conscription Cohort 

      Balog, Piroska; Janszky, Imre; Chen, Hua; Rafael, Beatrix; Hemmingsson, Tomas; László, Krisztina D. (Journal article; Peer reviewed, 2019)
      Objectives Increasing evidence suggests that low social support is associated with an elevated risk of coronary heart disease (CHD). Earlier studies in this field were conducted in predominantly middle-aged or older samples; ...
    • Symptoms of anxiety and depression and risk of acute myocardial infarction: the HUNT 2 study 

      Gustad, Lise Tuset; Laugsand, Lars Erik; Janszky, Imre; Dalen, Håvard; Bjerkeset, Ottar (Journal article; Peer reviewed, 2014)
      Aims The nature of the association of depression and anxiety with risk for acute myocardial infarction (AMI) remains unclear. We aimed to study the prospective association of single and recurrent self-reported symptoms of ...
    • Symptoms of anxiety and depression and risk of heart failure: The HUNT Study 

      Gustad, Lise Tuset; Laugsand, Lars Erik; Janszky, Imre; Dalen, Håvard; Bjerkeset, Ottar (Journal article; Peer reviewed, 2014)
      Aims The nature of the association of depression and anxiety with risk for acute myocardial infarction (AMI) remains unclear. We aimed to study the prospective association of single and recurrent self-reported symptoms of ...
    • Systematic assessment of prescribed medications and short-term risk of myocardial infarction - a pharmacopeia-wide association study from Norway and Sweden 

      Sen, Abhijit; Vardaxis, Ioannis; Lindqvist, Bo Henry; Brumpton, Ben Michael; Strand, Linn B; Bakken, Inger Johanne Landsjøåsen; Vatten, Lars Johan; Romundstad, Pål Richard; Ljung, Rickard; Mukamal, Kenneth Jay; Janszky, Imre (Journal article; Peer reviewed, 2019)
      Wholesale, unbiased assessment of Scandinavian electronic health-care databases offer a unique opportunity to reveal potentially important undiscovered drug side effects. We examined the short-term risk of acute myocardial ...
    • Transition into and out of daylight saving time and spontaneous delivery: a population-based study 

      László, Krisztina D.; Cnattingius, Sven; Janszky, Imre (Peer reviewed; Journal article, 2016)
      Objective To investigate whether the circadian rhythm disruption following the transition into and out of daylight saving time (DST) is associated with an increased risk of spontaneous delivery. Design We compared the ...
    • Variation in serum PCSK9 (proprotein convertase subtilisin/kexin type 9), cardiovascular disease risk, and an investigation of potential unanticipated effects of PCSK9 inhibition 

      Brumpton, Ben Michael; Fritsche, Lars; Zheng, Jie; Nielsen, Jonas Bille; Mannila, Maria Nastase; Surakka, Ida; Rasheed, Humaira; Vie, Gunnhild Åberge; Graham, Sarah E.; Gabrielsen, Maiken Elvestad; Laugsand, Lars Erik; Aukrust, Pål; Vatten, Lars Johan; Damås, Jan Kristian; Ueland, Thor; Janszky, Imre; Zwart, John-Anker; van't Hooft, Ferdinand M.; Seidah, Nabil Georges; Hveem, Kristian; Willer, Cristen; Smith, George Davey; Åsvold, Bjørn Olav (Peer reviewed; Journal article, 2019)
      PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors reduce serum LDL (low-density lipoprotein) cholesterol (LDL-C) by increasing uptake in the liver. Although some long-term trials have evaluated their safety, ...
    • White blood cell BRCA1 promoter methylation status and ovarian cancer risk 

      Lønning, Per Eystein; Berge, Elisabet Ognedal; Bjørnslett, Merete Pauline; Minsaas, Laura; Chrisanthar, Ranjan; Vetti, Hildegunn Høberg; Dulary, Cécile; Busato, Florence; Bjørneklett, Silje; Eriksen, Christine; Kopperud, Reidun Kristin; Axcrona, Ulrika; Davidson, Ben; Bjørge, Line; Evans, D. Gareth; Howell, Anthony; Salvesen, Helga; Janszky, Imre; Hveem, Kristian; Romundstad, Pål Richard; Vatten, Lars Johan; Tost, Jörg; Dørum, Anne; Knappskog, Stian (Journal article; Peer reviewed, 2018)
      Background: The role of normal tissue gene promoter methylation in cancer risk is poorly understood. Objective: To assess associations between normal tissue BRCA1 methylation and ovarian cancer risk. Design: 2 ...
    • Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants 

      Zhou, Bin; Bentham, James; Di Cesare, Mariachiara; Bixby, Honor; Danaei, Goodarz; Cowan, Melanie J.; Paciorek, Christopher J.; Singh, Gitanjali M; Hajifathalian, Kaveh; Bennett, James E.; Taddei, Cristina; Bilano, Ver; Carrillo-Larco, Rodrigo M.; Djalalinia, Shirin; Khatibzadeh, Shahab; Lugero, Charles; Peykari, Niloofar; Zhang, Wan Zhu; Lu, Yuan; Stevens, Gretchen A.; Riley, Leanne M.; Bovet, Pascal; Elliott, Paul; Gu, Dongfeng; Ikeda, Nayu; Jackson, Rod T; Joffres, Michel; Kengne, André Pascal; Laatikainen, Tiina; Lam, Tai Hing; Laxmaiah, Avula; Liu, Jing; Miranda, J. Jaime; Mondo, Charles K; Neuhauser, Hannelore K; Sundström, Johan; Smeeth, Liam; Sorić, Maroje; Woodward, Mark; Ezzati, Majid; Abarca-Gómez, Leandra; Abdeen, Ziad A.; Abdul Rahim, Hanan; Abu-Rmeileh, Niveen M.; Acosta-Cazares, Benjamin; Adams, Robert; Aekplakorn, Wichai; Afsana, Kaosar; Aguilar-Salinas, Carlos A.; Agyemang, Charles; Ahmadvand, Alireza; Ahrens, Wolfgang; Al Raddadi, Rajaa; Al Woyatan, Rihab; Ali, Mohamed M; Alkerwi, Ala'a; Aly, Eman; Amuzu, Antoinette; Amouyel, Philippe; Andersen, Lars Bo; Anderssen, Sigmund Alfred; Ängquist, Lars; Anjana, Ranjit Mohan; Ansong, Daniel; Aounallah-Skhiri, Hajer; Araújo, Joana; Ariansen, Inger Kristine; Aris, Tahir; Arlappa, Nimmathota; Aryal, Krishna; Arveiler, Dominique; Assah, Felix K.; Assunção, Maria Cecília; Avdicová, Mária; Azevedo, Ana; Azizi, Fereidoun; Babu, Bontha V; Bahijri, Suhad; Balakrishna, Nagalla; Bandosz, Piotr; Banegas, Jose R; Barbagallo, Carlo M.; Barcelo, Alberto; Barkat, Amina; Barros, Aluisio J.D.; Barros, Mauro V; Bata, Iqbal; Batieha, Anwar M.; Baur, Louise A.; Beaglehole, Robert; Ben Romdhane, Habiba; Benet, Mikhail; Benson, Lowell S.; Bernabe-Ortiz, Antonio; Bernotiene, Gailute; Bettiol, Heloisa; Bhagyalaxmi, Aroor; Bharadwaj, Sumit; Bhargava, Santosh K.; Bi, Yufang; Bikbov, Mukharram; Bjerregaard, Peter; Bjertness, Espen; Ekelund, Ulf; Graff-Iversen, Sidsel; Janszky, Imre; Kolle, Elin; Krokstad, Steinar; Laugsand, Lars Erik; Mathiesen, Ellisiv B.; Sen, Abhijit; Steene-Johannessen, Jostein; Vatten, Lars Johan; Wilsgaard, Tom (Journal article; Peer reviewed, 2016)
      Background Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence ...
    • Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults 

      Bentham, James; Di Cesare, Mariachiara; Bilano, Ver; Bixby, Honor; Zhou, Bin; Stevens, Gretchen A.; Riley, Leanne M.; Taddei, Cristina; Hajifathalian, Kaveh; Lu, Yuan; Savin, Stefan; Cowan, Melanie J.; Paciorek, Christopher J.; Chirita-Emandi, Adela; Hayes, Alison J; Katz, Joanne; Kelishadi, Roya; Kengne, André Pascal; Khang, Young-Ho; Laxmaiah, Avula; Li, Yanping; Ma, Jun; Miranda, J. Jaime; Mostafa, Aya; Neovius, Martin; Padez, Cristina; Rampal, Lekhraj; Zhu, Aubrianna; Bennett, James E.; Danaei, Goodarz; Bhutta, Zulfiqar A.; Ezzati, Majid; Abarca-Gómez, Leandra; Abdeen, Ziad A.; Hamid, Zargar Abdul; Abu-Rmeileh, Niveen M.; Acosta-Cazares, Benjamin; Acuin, Cecilia; Adams, Robert J.; Aekplakorn, Wichai; Afsana, Kaosar; Aguilar-Salinas, Carlos A.; Agyemang, Charles; Ahmadvand, Alireza; Ahrens, Wolfgang; Ajlouni, Kamel; Akhtaeva, Nazgul; Al-Hazzaa, Hazzaa M.; Al-Othman, Amani Rashed; Al-Raddadi, Rajaa; AlBuhairan, Fadia S.; AlDhukair, Shahla; Ali, Mohamed M; Ali, Osman; Alkerwi, Ala'a; Alvarez-Pedrerol, Mar; Aly, Eman; Amarapurkar, Deepak N.; Amouyel, Philippe; Amuzu, Antoinette; Andersen, Lars Bo; Anderssen, Sigmund Alfred; Andrade, Dolores S; Ängquist, Lars; Anjana, Ranjit Mohan; Aounallah-Skhiri, Hajer; Araújo, Joana; Ariansen, Inger Kristine; Aris, Tahir; Arlappa, Nimmathota; Arveiler, Dominique; Aryal, Krishna; Aspelund, Thor; Assah, Felix K.; Assunção, Maria Cecília; Aung, May Soe; Avdicová, Mária; Azevedo, Ana; Azizi, Fereidoun; Babu, Bontha V; Bahijri, Suhad; Baker, Jennifer L.; Balakrishna, Nagalla; Bamoshmoosh, Mohamed; Banach, Maciej; Bandosz, Piotr; Banegas, Jose R; Barbagallo, Carlo M.; Barcelo, Alberto; Barkat, Amina; Barros, Aluisio J.D.; Barros, Mauro V.G.; Bata, Iqbal; Biehl, Anna Månsson; Bjertness, Espen; Bjertness, Marius Bergsmark; Ekelund, Ulf; Graff-Iversen, Sidsel; Janszky, Imre; Kolle, Elin; Krokstad, Steinar; Laugsand, Lars Erik; Mathiesen, Ellisiv B.; Meisfjord, Jørgen Rajan; Meyer, Haakon E; Sen, Abhijit; Steene-Johannessen, Jostein; Vatten, Lars Johan; Wilsgaard, Tom (Journal article; Peer reviewed, 2017)
      Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index ...