Browsing NTNU Open by Author "Moyano-Galceran, Lidia"
Now showing items 1-5 of 5
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Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality
Jukonen, Joonas; Moyano-Galceran, Lidia; Höpfner, Katrin; Pietilä, Elina A.; Lehtinen, Laura; Huhtinen, Kaisa; Gucciardo, Erika; Hynninen, Johanna; Hietanen, Sakari; Grénman, Seija; Ojala, Päivi M.; Carpén, Olli; Lehti, Kaisa (Peer reviewed; Journal article, 2021)Erythropoietin producing hepatocellular (Eph) receptors and their membrane-bound ligands ephrins are variably expressed in epithelial cancers, with context-dependent implications to both tumor-promoting and -suppressive ... -
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance
Pietilä, Elina A.; Gonzalez-Molina, Jordi.; Moyano-Galceran, Lidia; Jamalzadeh, Sanaz; Zhang, Kaiyang; Lehtinen, Laura; Turunen, S Pauliina; Martins, Tomás A; Gultekin, Okan; Lamminen, Tarja; Kaipio, Katja; Joneborg, Ulrika; Hynninen, Johanna; Hietanen, Sakara; Grénman, Seija; Lehtonen, Rainer; Hautaniemi, Sampsa; Carpén, Olli; Carlson, Joseph W.; Lehti, Kaisa (Peer reviewed; Journal article, 2021)Due to its dynamic nature, the evolution of cancer cell-extracellular matrix (ECM) crosstalk, critically affecting metastasis and treatment resistance, remains elusive. Our results show that platinum-chemotherapy itself ... -
Crosstalk Between Cancer Associated Fibroblasts and Cancer Cells in Scirrhous Type Gastric Cancer
Miki, Yuichiro; Yashiro, Masakazu; Moyano-Galceran, Lidia; Sugimoto, Atsushi; Ohira, Masaichi; Lehti, Kaisa (Peer reviewed; Journal article, 2020)Gastric cancer (GC) is the third leading cause among all cancer deaths globally. Although the treatment outcome of GC has improved, the survival of patients with GC at stages III and IV remains unsatisfactory. Among several ... -
FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation
Gultekin, Okan; Gonzalez-Molina, Jordi; Hardell, Elin; Moyano-Galceran, Lidia; Mitsios, Nicholas; Mulder, Jan; Kokaraki, Georgia; Isaksson, Anders; Sarhan, Dhifaf; Lehti, Kaisa; Carlson, Joseph W. (Peer reviewed; Journal article, 2021)Uterine sarcomas are rare but deadly malignancies without effective treatment. Immunotherapy is a promising new approach to treat these tumors but has shown heterogeneous effects in sarcoma patients. With the goal of ... -
Mechanical Confinement and DDR1 Signaling Synergize to Regulate Collagen-Induced Apoptosis in Rhabdomyosarcoma Cells
Gonzalez-Molina, Jordi; Kirchhof, Katharina Miria; Rathod, Bhavik; Moyano-Galceran, Lidia; Calvo-Noriega, Maria; Kokaraki, Georgia; Bjørkøy, Astrid; Ehnman, Monika; Carlson, Joseph W.; Lehti, Kaisa (Journal article; Peer reviewed, 2022)