Browsing NTNU Open by Author "White, Linda"
Now showing items 1-15 of 15
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Alpha-synuclein measured in cerebrospinal fluid from patients with Alzheimer's disease, mild cognitive impairment, or healthy controls: a two year follow-up study
Sando, Sigrid Botne; Albrektsen, Grethe; Møller, Ina; White, Linda; Berge, Guro; Grøntvedt, Gøril Rolfseng; Lauridsen, Camilla; Bråthen, Geir (Journal article; Peer reviewed, 2016)Background α-Synuclein has been proposed as a potential biomarker for Alzheimer’s disease (AD) and amnestic mild cognitive impairment (aMCI). However, results from α-synuclein measurements in cerebrospinal fluid (CSF) ... -
Amyloid beta 1-43 as a potential biomarker for the detection of early Alzheimer’s disease
Lauridsen, Camilla (Doctoral theses at NTNU;2017:219, Doctoral thesis, 2017) -
Angiotensin-converting enzyme gene insertion/deletion polymorphism in migraine patients
Tronvik, Erling; Stovner, Lars Jacob; Bovim, Gunnar; White, Linda; Gladwind, AJ; Owen, k; Schrader, Harald (Journal article; Peer reviewed, 2008)Background: The main objective of this study was to investigate the angiotensin converting enzyme (ACE) genotype as a possible risk factor for migraine (both with and without aura) compared to controls. We also wanted ... -
APOE ε4 lowers age at onset and is a high risk factor for Alzheimer's disease; a case control study from central Norway
Sando, Sigrid Botne; Melquist, Stacey; Cannon, Ashley; Hutton, Michael; Sletvold, Olav; Saltvedt, Ingvild; White, Linda; Lydersen, Stian; Aasly, Jan (Journal article; Peer reviewed, 2008)Background: The objective of this study was to analyze factors influencing the risk and timing of Alzheimer's disease (AD) in central Norway. The APOE ε4 allele is the only consistently identified risk factor for late ... -
Cerebrospinal fluid A?43 is reduced in early-onset compared to late-onset Alzheimer's disease, but has similar diagnostic accuracy to A?42
Lauridsen, Camilla; Sando, Sigrid Botne; Møller, Ina; Berge, Guro; Pomary, Precious Kwadzo; Grøntvedt, Gøril Rolfseng; Salvesen, Øyvind; Bråthen, Geir; White, Linda (Journal article; Peer reviewed, 2017)Background: Amyloid beta 1–43 (Aβ43) may be a useful additional biomarker for diagnosing Alzheimer’s disease (AD). We have investigated cerebrospinal fluid (CSF) levels of Aβ43 in patients with early-onset AD in contrast ... -
Cerebrospinal Fluid Levels of Amyloid Beta 1-43 in Patients with Amnestic Mild Cognitive Impairment or Early Alzheimer's Disease: A 2-Year Follow-Up Study
Lauridsen, Camilla; Sando, Sigrid Botne; Shabnam, Adiba; Møller, Ina; Berge, Guro; Grøntvedt, Gøril Rolfseng; Bakken, Inger Johanne; Salvesen, Øyvind; Bråthen, Geir; White, Linda (Journal article; Peer reviewed, 2016)Introduction: Biomarkers that will reliably predict the onset of Alzheimer’s disease (AD) are urgently needed. Although cerebrospinal fluid (CSF) amyloid beta 1–42 (Aβ42), total tau, and phosphorylated tau can be used to ... -
Cerebrospinal fluid levels of amyloid beta 1-43 mirror 1-42 in relation to imaging biomarkers of Alzheimer's disease
Almdahl, Ina; Lauridsen, Camilla; Selnes, Per; Kalheim, Lisa Flem; Coello, Christopher; Gajdzik, Beata; Møller, Ina; Wettergreen, Marianne; Grambaite, Ramune; Bjørnerud, Atle; Bråthen, Geir; Sando, Sigrid Botne; White, Linda; Fladby, Tormod (Journal article; Peer reviewed, 2017) -
Changes to intermediary metabolites in sporadic and LRRK2 Parkinson's disease demonstrated by proton magnetic resonance spectroscopy
Aasly, Jan; Sæther, Oddbjørn; Johansen, Krisztina Kunszt; Bathen, Tone Frost; Giskeødegård, Guro F.; White, Linda (Peer reviewed; Journal article, 2015)Background. Parkinson’s disease (PD) remains a clinical diagnosis and biomarkers are needed to detect the disease as early as possible. Genetically determined PD provides an opportunity for studying metabolic differences ... -
Metabolomic profiling in LRRK2-related Parkinson's disease
Johansen, Krisztina; Wang, Lei; Aasly, Jan; White, Linda; Matson, Wayne R.; Henchcliffe, Claire; Flint Beal, M.; Bogdanov, Mikhail (Journal article; Peer reviewed, 2009)Background: Mutations in LRRK2 gene represent the most common known genetic cause of Parkinson's disease (PD). Methodology/Principal Findings: We used metabolomic profiling to identify biomarkers that are associated ... -
Pain, autonomic activation and muscular activation to experimentally-induced cognitive stress in headache patients
Leistad, Rune Bang (Doktoravhandlinger ved NTNU, 1503-8181; 2007:186, Doctoral thesis, 2007)Background and objectives Stress is in several studies mentioned as the most frequent trigger of headache. Nevertheless, the exact mechanisms by which stress induces headache is poorly understood and relatively few studies ... -
Polygenic overlap between C-reactive protein, plasma lipids, and Alzheimer disease
Desikan, Rahul S.; Schork, Andrew J.; Wang, Yunpeng; Thompson, Wesley K.; Dehghan, Abbas; Ridker, Paul M.; Chasman, Daniel I.; McEvoy, Linda K.; Holland, Dominic; Chen, Chi-Hua; Karow, David S.; Brewer, James B.; Hess, Christopher P.; Williams, Julie; Sims, Rebecca; O'Donovan, Michael C.; Choi, Seung Hoan; Bis, Joshua C.; Ikram, M. Arfan; Gudnason, Vilmundur; DeStefano, Anita L.; Van Der Lee, Sven J.; Psaty, Bruce M.; Van Duijn, Cornelia M.; Launer, Lenore; Seshadri, Sudha; Pericak-Vance, Margaret A.; Mayeux, Richard; Haines, Jonathan L.; Farrer, Lindsay A.; Hardy, John; Ulstein, Ingun; Aarsland, Dag; Fladby, Tormod; White, Linda; Sando, Sigrid Botne; Rongve, Arvid; Witoelar, Aree; Djurovic, Srdjan; Hyman, Bradley T.; Snædal, Jon; Steinberg, Stacy; Stefansson, Hreinn; Stefánsson, Kári; Schellenberg, Gerard D.; Andreassen, Ole Andreas; Dale, Anders (Journal article; Peer reviewed, 2015)Background—Epidemiological findings suggest a relationship between Alzheimer disease (AD), inflammation, and dyslipidemia, although the nature of this relationship is not well understood. We investigated whether this ... -
Potential biomarkers and other factors relevant for dementia
Berge, Guro (Doctoral theses at NTNU;2016:102, Doctoral thesis, 2016) -
Proteins associated with core biomarkers in early Alzheimer`s disease: A pilot study of levels in cerebrospinal fluid, serum or plasma
Medbøen, Ingrid Tøndel (Master thesis, 2014)Background:The cerebrospinal fluid (CSF) biomarkers amyloid-beta 42 (Aβ42), total tau (T-tau) and phosphorylated tau (P-tau) are considered to reflect core pathological features of Alzheimer’s disease (AD), and have ... -
Studies of the autoantigen Pso p27 in the cerebrospinal fluid of patients with multiple sclerosis
Hvaring, Charlotte Maria (Master thesis, 2013)Background: The many similarities between autoimmune diseases point to a common origin, also known as the autoimmune tautology. Pso p27 is an auto-antigen and has been found in several autoimmune diseases, first in psoriasis ... -
The brain structural and cognitive basis of odor identification deficits in mild cognitive impairment and Alzheimer's disease
Kjelvik, Grete; Saltvedt, Ingvild; White, Linda; Stenumgård, Pål Sigurd; Sletvold, Olav; Engedal, Knut; Skåtun, Kristina Cecilie; Lyngvær, Ann Kristin Rian; Steffenach, Hill Aina; Håberg, Asta (Journal article; Peer reviewed, 2014)Background: The objectives of this study were to explore the relationship between olfactory impairment, cognitive measures, and brain structure volumes in healthy elderly individuals, compared to patients with amnestic ...