• A 4-year follow-up of patients with medication-overuse headache previously included in a randomized multicentre study 

      Hagen, Knut; Albretsen, Claus; Vilming, Steinar; Salvesen, Rolf; Grønning, Marit; Helde, Grethe; Gravdahl, Gøril Bruvik; Zwart, John-Anker; Stovner, Lars Jacob (Journal article; Peer reviewed, 2011)
    • Angiotensin-converting enzyme gene insertion/deletion polymorphism in migraine patients 

      Tronvik, Erling; Stovner, Lars Jacob; Bovim, Gunnar; White, Linda; Gladwind, AJ; Owen, k; Schrader, Harald (Journal article; Peer reviewed, 2008)
      Background: The main objective of this study was to investigate the angiotensin converting enzyme (ACE) genotype as a possible risk factor for migraine (both with and without aura) compared to controls. We also wanted ...
    • Association between blood pressure measures and recurrent headache in adolescents: cross-sectional data from the HUNT-Youth study 

      Tronvik, Erling; Zwart, John-Anker; Hagen, Knut; Dyb, Grete; Holmen, Turid Lingaas; Stovner, Lars Jacob (Journal article; Peer reviewed, 2011)
      The relationship between blood pressure and headache in youth has not been explored and the objective of the present study was to provide data on this association in an adolescent population. Cross-sectional data from a ...
    • Autonomic and muscular responses and recovery to one-hour laboratory mental stress in healthy subjects 

      Nilsen, Kristian Bernhard; Sand, Trond; Stovner, Lars Jacob; Leistad, Rune Bang; Westgaard, Rolf Harald (Journal article; Peer reviewed, 2007-08-14)
      Background: Stress is a risk factor for musculoskeletal pain. We wanted to explore stress related physiology in healthy subjects in order to gain insight into mechanisms of pain development which may relate to the ...
    • Cardiovascular responses to cognitive stress in patients with migraine and tension-type headache 

      Leistad, Rune Bang; Sand, Trond; Nilsen, Kristian Bernhard; Westgaard, Rolf Harald; Stovner, Lars Jacob (Journal article; Peer reviewed, 2007)
      Background: The purpose of this study was to investigate the temporal relationship between autonomic changes and pain activation in migraine and tension-type headache induced by stress in a model relevant for everyday ...
    • Cerebral cortical dimensions in headache sufferers aged 50-66 years: a population-based imaging study in the Nord-Trondelag Health Study (HUNT-MRI) 

      Husøy, Andreas Kattem; Håberg, Asta Kristine; Rimol, Lars Morten; Hagen, Knut; Vangberg, Torgil Riise; Stovner, Lars Jacob (Journal article; Peer reviewed, 2019)
      Based on previous clinic-based magnetic resonance imaging studies showing regional differences in the cerebral cortex between those with and without headache, we hypothesized that headache sufferers have a decrease in ...
    • Clinical and vascular responses to propranolol and candesartan in migraine patients: A randomized controlled clinical trial 

      Barzenje, Aros D; Gjesdal, Knut; Winsvold, Bendik K S; Småstuen, Milada Cvancarova; Stovner, Lars Jacob; Gravdahl, Gøril Bruvik; Nilsen, Kristian Bernhard (Journal article, 2020)
      Background: Both propranolol and candesartan are prophylactic drugs for migraine, but with unknown mechanisms of action. The objectives of the present study were to investigate these drugs’ effects on arterial wall dynamics ...
    • Continuous positive airway pressure in cluster headache: A randomized, placebo-controlled, triple-blind, crossover study 

      Gravdahl, Gøril Bruvik; Aakerøy, Lars; Stovner, Lars Jacob; Engstrøm, Morten; Müller, Kai Ivar; Bjørk, Marte-Helene; Tronvik, Erling Andreas (Peer reviewed; Journal article, 2023)
      Abstract Background Oxygen inhalation aborts cluster headache attacks, and case reports show the effect of continuous positive airway pressure. The aim of this study was to investigate the prophylactic effect of continuous ...
    • Diagnosis, prevalence estimation and burden measurement in population surveys of headache: presenting the HARDship questionnaire 

      Steiner, Timothy J.; Gururaj, Gopalakrishna; Andree, Colette; Katsarava, Zaza; Ayzenberg, Ilya; Yu, Shengyuan; Al Jumah, Mohammed A; Tekle-Haimanot, Redda; Birbeck, Gretchen; Herekar, Arif; Linde, Mattias; Mbewe, Edouard; Manandhar, Kedar; Risal, Ajay; Jensen, Rigmor; Queiroz, Luiz Paulo; Scher, Ann; Wang, Shuu-Jiun; Stovner, Lars Jacob (Journal article; Peer reviewed, 2014)
      The global burden of headache is very large, but knowledge of it is far from complete and needs still to be gathered. Published population-based studies have used variable methodology, which has influenced findings and ...
    • Diffusion tensor imaging in middle-aged headache sufferers in the general population: A cross-sectional population-based imaging study in the Nord-Trøndelag health study (HUNT-MRI) 

      Husøy, Andreas Kattem; Eikenes, Live; Håberg, Asta; Hagen, Knut; Stovner, Lars Jacob (Journal article; Peer reviewed, 2019)
      Background Several studies have investigated white matter with diffusion tensor imaging (DTI) in those suffering from headache, but so far only in clinic based samples and with conflicting results. Methods In the present ...
    • Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools 

      Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Winsvold, Bendik K S; O'Connell, Kevin S; Frei, Oleksandr; Shadrin, Alexey; Cheng, Weiqiu; Bettella, Francesco; Rødevand, Linn; Ødegaard, Ketil Joachim; Fan, Chun C; Pirinen, Matti J; Hautakangas, Heidi M; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Tronvik, Erling Andreas; Kristoffersen, Espen Saxhaug; Zwart, John Anker Henrik; Nielsen, Jonas Bille; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Stovner, Lars Jacob; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir Lingaas; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Dale, Anders; Djurovic, Srdjan; Smeland, Olav Bjerkehagen; Andreassen, Ole (Peer reviewed; Journal article, 2022)
      Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic neurotransmission are ...
    • Do incident musculoskeletal complaints influence mortality? The Nord-Trøndelag Health study 

      Åsberg, Anders Nikolai; Hagen, Knut; Stovner, Lars Jacob; HEUCH, INGRID; Zwart, John-Anker; Winsvold, Bendik K S (Journal article; Peer reviewed, 2018)
      Background Musculoskeletal complaints (MSC) are common in the general population, causing a major disease burden to the individual and society. The association between MSC and mortality is still unclear. To our knowledge, ...
    • Does health differ between participants and non-participants in the MRI-HUNT study, a population based neuroimaging study? The Nord-Trøndelag health studies 1984-2009 

      Honningsvåg, Lasse-Marius; Linde, Mattias; Håberg, Asta; Stovner, Lars Jacob; Hagen, Knut (Journal article; Peer reviewed, 2012)
      Background Bias with regard to participation in epidemiological studies can have a large impact on the generalizability of results. Our aim was to investigate the direction and magnitude of potential bias by comparing ...
    • Does pain sensitivity change by migraine phase? A blinded longitudinal study 

      Hagen, Knut; Omland, Petter Moe; Stovner, Lars Jacob; Sand, Trond Halfdan; Uglem, Martin; Tronvik, Erling Andreas; Nilsen, Kristian Bernhard; Linde, Anders Mattias (Journal article; Peer reviewed, 2016)
      Objective: Studies suggest that pain thresholds may be altered before and during migraine headaches, but it is still debated if a central or peripheral dysfunction is responsible for the onset of pain in migraine. The ...
    • FollowTheSutures: Piloting a new way to administer onabotulinumtoxinA for chronic migraine. 

      Stovner, Lars Jacob; Hagen, Knut; Tronvik, Erling Andreas; Gravdahl, Gøril Bruvik; Burstein, Rami; Dodick, David W. (Peer reviewed; Journal article, 2022)
      Background Anatomical and experimental data indicate that onabotulinimtoxin A could be more efficient and cost-effective for treating chronic migraine with injections targeting the cranial sutures, where collaterals from ...
    • Gir ACE-hemmere og angiotensinreseptorantagonister økt risiko for alvorlig covid-19? 

      Aamodt, Anne Hege; Bjørk, Marte-Helene; Tronvik, Erling Andreas; Buanes, Eirik Alnes; Stovner, Lars Jacob; Atar, Dan (Peer reviewed; Journal article, 2020)
      Hypertensjon og diabetes mellitus er risikofaktorer for alvorlig covid-19. Det er blitt reist spørsmål om hvorvidt denne assosiasjonen er relatert til bruk av ACE-hemmere og angiotensin II-reseptorblokkere.
    • The Global Campaign turns 18: a brief review of its activities and achievements 

      Steiner, Timothy J.; Birbeck, Gretchen L.; Jensen, Rigmor H.; Martelletti, Paolo; Stovner, Lars Jacob; Uluduz, Derya; Leonardi, Matilde; Olesen, Jes; Katsarava, Zaza (Peer reviewed; Journal article, 2022)
    • The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates 

      Stovner, Lars Jacob; Hagen, Knut; Linde, Mattias; Steiner, Timothy J. (Peer reviewed; Journal article, 2022)
      Background According to the Global Burden of Disease (GBD) study, headache disorders are among the most prevalent and disabling conditions worldwide. GBD builds on epidemiological studies (published and unpublished) ...
    • Global, regional, and national burden of migraine and tension-type headache, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016 

      Stovner, Lars Jacob; Nichols, Emma; Steiner, Timothy J.; Abd-Allah, Foad; Abdelalim, Ahmed; Al-Raddadi, Rajaa M.; Ansha, Mustafa Geleto; Barac, Aleksandra; Bensenor, Isabela M.; Doan, Linh Phuong; Edessa, Dumessa; Endres, Matthias; Foreman, Kyle J.; Gankpe, Fortune Gbetoho; Gopalkrishna, Gururaj; Goulart, Alessandra C.; Gupta, Rahul; Hankey, Graeme J.; Hay, Simon I.; Hegazy, Mohamed I.; Hilawe, Esayas Haregot; Kasaeian, Amir; Kassa, Dessalegn H.; Khalil, Ibrahim; Khang, Young-Ho; Khubchandani, Jagdish; Kim, Yun Jin; Kokubo, Yoshihiro; Mohammed, Mohammed A.; Moradi-Lakeh, Maziar; Nguyen, Huong Lan Thi; Nirayo, Yirga Legesse; Qorbani, Mostafa; Ranta, Anna; Roba, Kedir T.; Safiri, Saeid; Santos, Itamar S.; Satpathy, Maheswar; Sawhney, Monika; Shiferaw, Mekonnen Sisay; Shiue, Ivy; Smith, Mari; Szoeke, Cassandra E.I.; Truong, Nu Thi; Venketasubramanian, Narayanaswamy; Weldegwergs, Kidu Gidey; Westerman, Ronny; Wijeratne, Tissa; Tran, Bach Xuan; Yonemoto, Naohiro; Feigin, Valery L.; Vos, Theo; Murray, Christopher J.L. (Journal article; Peer reviewed, 2018)
      Background Through the Global Burden of Diseases, Injuries, and Risk Factors (GBD) studies, headache has emerged as a major global public health concern. We aimed to use data from the GBD 2016 study to provide new estimates ...
    • Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016 

      Feigin, Valery L.; Nichols, Emma; Alam, Tahiya; Bannick, Marlena S.; Beghi, Ettore; Blake, Natacha; Culpepper, William J.; Dorsey, E. Ray; Elbaz, Alexis; Ellenbogen, Richard G.; Fisher, James L.; Fitzmaurice, Christina; Giussani, Giorgia; Glennie, Linda; James, Spencer L.; Johnson, Catherine O.; Kassebaum, Nicholas J.; Logroscino, Giancarlo; Marin, Benoit; Mountjoy-Venning, W. Cliff; Nguyen, Minh; Ofori-Aseno, Richard; Patel, Anoop P.; Piccininni, Marco; Roth, Gregory A.; Steiner, Timothy J.; Stovner, Lars Jacob; Szoeke, Cassandra E.I.; Theadom, Alice; Vollset, Stein Emil; Wallin, Mitchell Taylor; Wright, Claire; Zunt, Joseph R.; Abbasi, Nooshin; Abd-Allah, Foad; Abdelalim, Ahmed; Abdollahpour, Ibrahim; Aboyans, Victor; Abraha, Haftom Niguse; Acharya, Dilaram; Adamu, Abdu A.; Adebayo, Oladimeji M.; Adeoye, Abiodun Moshood; Adsuar, Jose C.; Afarideh, Mohsen; Agrawal, Sutapa; Ahmadi, Alireza; Kisa, Adnan; Weiderpass, Elisabete; Winkler, Andrea Sylvia; Truelsen, Thomas Clement; McGrath, J J; Fereshtehnejad, Seyed-Mohammad; Havmoeller, R; Dharmaratne, S D; Hay, S I; Khalil, I A; Mokdad, A H; Nixon, M R; Reinig, Nickolas; Roberts, N L S; Smith, M; Whiteford, H A; Naghavi, M; Murray, C J L; Vos, T; Morrison, S D; Krishnamurthi, R V; Te Ao, B J; Kalani, R; Meretoja, Atte; Sahathevan, Ramesh; Mackay, M T; Wijeratne, Tissa; Farzaei, M; Heydarpour, Fatemeh; Khazaie, H; Moradinazar, Mehdi; Naderi, M; Najafi, Farid; Salimi, Yahya; Rajati, Fatemeh; Safari-Faramani, Roya; Salehi Zahabi, S; Siabani, Soraya; Soofi, Moslem; Rezaeian, Shahab; Awasthi, Ashish; Zodpey, S; Farzadfar, F; Irvani, S N; Hegazy, M I; Kassa, T D; Nirayo, Y L; Belachew, A B; Gebre, A K; Gebremichael, T G; Tsadik, A G; Yimer, E M; Gezae, K; Hagos, T B; Kahsay, Amaha; Degefa, M G; Mengistu, D T; Meles, H G; Wiysonge, C S; Nyasulu, P S; Seedat, Soraya; Stein, D J; Akinyemi, R O; Owolabi, M O; Ahmed, M B; Duken, E; Feyissa, G T; Aichour, Amani Nidhal; Al-Eyadhy, Ayman; Sobaih, B H; Temsah, Mohamad-Hani; Altirkawi, Khalid; Aljunid, S M; Alvis-Guzman, Nelson; Antonio, C T; Lopez, J F; Arnlöv, Johan; Carrero, J J; El-Khatib, Ziad; Christensen, H; Kokubo, Yoshihiro; Kucuk Bicer, Burcu; Lansingh, V C; Linn, Shai; Mahotra, N B; Majdan, Marek; Mendoza, Walter; Meretoja, T J; Mestrovic, Tomislav; Miazgowski, B; Mirrakhimov, E M; Mustafa, Ghulam; Zaman, S; Ningrum, DNA; Nguyen, C T; Petzold, M; Postma, M J; Ranta, Anna; Rios González, C M; Saddik, B; She, Jun; Sigurvinsdottir, Rannveig; Silveira, D A; Sobhani, Soheila (Journal article; Peer reviewed, 2019)
      Background: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is ...