Browsing NTNU Open by Author "Stokke, Bjørn Torger"
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Actuation of a Hyperelastic PDMS Membrane Suspended inside a Microfluidic Channel: From Computer Simulation to Microfabrication
Ribe, Jonas Myren (Master thesis, 2012)This Master-project was done in the Department of Physics at NTNU in the spring of 2012. The project develops micro- and nanofabrication processes useful for lab-on-a-chip systems. These systems aim to scale down and ... -
Atomic force microscopy measurements for the surface and the interaction characterization to optimize the surface patterning for bacterial micro arrays
Muri, Harald Ian Damm Irgens (Master thesis, 2013)This Master project was done in the Department of Physics at NTNU in the spring2013. The project focus on the optimization of micro patterning techniques to producemicro arrays for single bacterial cell studies. The micro ... -
Buckling initiation in layered hydrogels during transient swelling
Ilseng, Arne; Prot, Victorien Emile; Skallerud, Bjørn Helge; Stokke, Bjørn Torger (Journal article; Peer reviewed, 2019)Subjected to compressive stresses, soft polymers with stiffness gradients can display various buckling patterns. These compressive stresses can have different origins, like mechanical forces, temperature changes, or, for ... -
Competitive ligand exchange of crosslinking ions for ionotropic hydrogel formation.
Bassett, David; Håti, Armend Gazmeno; Melø, Thor Bernt; Stokke, Bjørn Torger; Sikorski, Pawel (Journal article; Peer reviewed, 2016)Currently there are limitations to gelation strategies to form ionically crosslinked hydrogels, derived in particular from a lack of control over the release kinetics of crosslinking ions, which severely restrict applications. ... -
Constrained Hydrogel swelling in Biological Sensors: A Finite Element Method Approach
Sveinsson, Hrafn Mar (Master thesis, 2012)Material models has been developed for anionic and/or cationic hydrogels, with a simulation framework implemented in MATLAB and the finite element software ABAQUS. The geometry of the simulations is a hemispheroidal hydrogel, ... -
Cyclodextrin triggered dimensional changes of polysaccharide nanogel integrated hydrogels at nanometer resolution
Gao, Ming; Toita, Sayaka; Sawada, Shin-ichi; Akiyoshi, Kazunara; Stokke, Bjørn Torger (Journal article; Peer reviewed, 2013)High resolution monitoring of dimensional changes of cholesterol bearing pullulan (CHP) hydrogel was performed as a model for materials dimensional changes associated with drug delivery. Hydrogels consisting of methacryloyl ... -
Dense carbon-nanotube coating scaffolds stimulate osteogenic differentiation of mesenchymal stem cells
Mori, Hideki; Ogura, Yuko; Enomoto, Kenta; Hara, Masayuki; Maurstad, Gjertrud; Stokke, Bjørn Torger; Kitamura, Shinichi (Peer reviewed; Journal article, 2020)Carbon nanotubes (CNTs) have desirable mechanical properties for use as biomaterials in orthopedic and dental area such as bone- and tooth- substitutes. Here, we demonstrate that a glass surface densely coated with ... -
Determination of the energy landscape among biological macromolecules: The mucin-alginate case
Safaee Adl, Patricia (Master thesis, 2013)Luminal epithelial surfaces of our body are covered by a secreted layer of mucus consisting chiefly of water (95%), high molecular weight polymeric glycoproteins known as mucins (3%), and other small molecules (2%). If ... -
Development of a Smartphone-based diagnostic Tool for Jaundice
Vartdal, Gunnar (Master thesis, 2014)Jaundice is the cause of an estimated 114,100 deaths among newborn annually. Most of these deaths occur in the poorest regions of the world where current diagnostic technologies are too expensive. In this thesis, several ... -
Direct Determination of Chitosan–Mucin Interactions Using a Single-Molecule Strategy: Comparison to Alginate–Mucin Interactions
Haugstad, Kristin Elisabeth; Håti, Armend Gazmeno; Nordgård, Catherine Taylor; Adl, Patricia S.; Maurstad, Gjertrud; Sletmoen, Marit; Draget, Kurt Ingar; Dias, Rita de Sousa; Stokke, Bjørn Torger (Journal article; Peer reviewed, 2015)Aqueous chitosan possesses attractive interaction capacities with various molecular groups that can be involved in hydrogen bonds and electrostatic and hydrophobic interactions. In the present paper, we report on the direct ... -
Effect of Glutaminase Inhibition in Basal-Like Patient-Derived Xenografts Analyzed by Magnetic Resonance Spectroscopy
Henriksen, Ida Marie (Master thesis, 2017)Breast cancer is today the leading cause for cancer related deaths among women in Europe. Decreased mortality among breast cancer patients has been observed over the last twenty years, where development and use of targeted ... -
Energy Landscape of Alginate-Epimerase Interactions Assessed by Optical Tweezers and Atomic Force Microscopy
Håti, Armend Gazmeno; Aachmann, Finn Lillelund; Stokke, Bjørn Torger; Skjåk-Bræk, Gudmund; Sletmoen, Marit (Journal article, 2015)Mannuronan C-5 epimerases are a family of enzymes that catalyze epimerization of alginates at the polymer level. This group of enzymes thus enables the tailor-making of various alginate residue sequences to attain various ... -
Evanescent light field trapping and transport of micro- and nanocrystals of biological macromolecules on a waveguide for serial crystallography.
Fuglerud, Silje Skeide (Master thesis, 2016)A microfluidic evanescent field optical tweezer system was tested and developed for sample delivery of micro- and nanocrystals in serial crystallography. The fluid line was enforced, and the setup changed from vacuum ... -
High resolution interferometry as a tool for characterization of swelling of weakly charged hydrogels subjected to amphiphile and cyclodextrin exposure
Gao, Ming; Gawel, Kamila; Stokke, Bjørn Torger (Journal article; Peer reviewed, 2013)A high resolution interferometric technique was used to determine swelling behavior of weakly charged polyacrylamide hydrogels in the presence of oppositely charged surfactants and subsequent exposure to cyclodextrins. ... -
Impact of Silanization Parameters and Antibody Immobilization Strategy on Binding Capacity of Photonic Ring Resonators
Arnfinnsdottir, Nina Bjørk; Chapman, Cole A; Bailey, Ryan C; Aksnes, Astrid; Stokke, Bjørn Torger (Peer reviewed; Journal article, 2020)Ring resonator-based biosensors have found widespread application as the transducing principle in “lab-on-a-chip” platforms due to their sensitivity, small size and support for multiplexed sensing. Their sensitivity is, ... -
Influence of oligoguluronates on alginate gelation and on alginate gel properties
Padoł, Anna Maria (Doctoral thesis at NTNU;2016:59, Doctoral thesis, 2016)Alginates are very abundant material in nature, mostly known for its gelling ability. Alginate is a family of linear copolymers of β-D-mannuronic acid and α-L-guluronic acid. Due to its biocompatibility, nontoxicity and ... -
Interactions between the breast cancer-associated MUC1 mucins and C-type lectin characterized by optical tweezers
Hadjialirezaei, Soosan; Picco, Gianfranco; Beatson, Richard; Burchell, Joy; Stokke, Bjørn Torger; Sletmoen, Marit (Journal article; Peer reviewed, 2017)Carbohydrate–protein interactions govern many crucial processes in biological systems including cell recognition events. We have used the sensitive force probe optical tweezers to quantify the interactions occurring between ... -
Local structure of Ca2+ alginate hydrogels gelled via competitive ligand exchange and measured by small angle X-ray scattering
Yamamoto, K; Yuguchi, Yoshiaki; Stokke, Bjørn Torger; Sikorski, Pawel; Bassett, David (Journal article; Peer reviewed, 2019)Alginates, being linear anionic co-polymers of 1,4-linked residues β-d-ManA (M) and α-l-GulA (G), are widely applied as hydrogel biomaterials due to their favourable in vivo biocompatibility and convenient ionic crosslinking. ... -
Macromolecular interactions at the single-molecule level - Fluctuation analysis of bound states
Bruvold, Are Sæle (Master thesis, 2018)The recognition, binding and release of macromolecules are precisely orchestrated in a stochastic interplay governing all enzymatic, immunological and cellular processes. Deciphering this complex synergy in order to ... -
Microarrays for the study of compartmentalized microorganisms in alginate microbeads and (W/O/W) double emulsions
Håti, Armend Gazmeno; Arnfinnsdottir, Nina Bjørk; Østevold, Camilla; Sletmoen, Marit; Etienne, Gianluca; amstad, esther; Stokke, Bjørn Torger (Journal article; Peer reviewed, 2016)Understanding of cells has mainly been achieved through analysis of average properties of large cellular populations. The increased awareness of cellular heterogeneity in various biological systems, spans from single ...