Blar i NTNU Open på forfatter "Solheim, Ole"
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18F-FACBC PET/MRI in diagnostic assessment and neurosurgery of gliomas
Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Hong, Yan Dai; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2019)Purpose This pilot study aimed to evaluate the amino acid tracer 18F-FACBC with simultaneous PET/MRI in diagnostic assessment and neurosurgery of gliomas. Materials and Methods Eleven patients with suspected primary or ... -
Accuracy and Complication Rates of External Ventricular Drain Placement With Twist Drill and Bolt System Versus Standard Trephine and Tunnelation: A Retrospective Population-Based Study
Mansoor, Nadia Mauland; Madsbu, Mattis Aleksander; Mansoor, Nina M.; Trønnes, Andreas; Fredriksli, Oddrun; Salvesen, Øyvind; Jakola, Asgeir S; Solheim, Ole; Gulati, Sasha (Peer reviewed; Journal article, 2020)Background: An external ventricular drain (EVD) is typically indicated in the presence of hydrocephalus and increased intracranial pressure (ICP). Procedural challenges have prompted the development of different methods ... -
Advancements in predicting outcomes in patients with glioma: a surgical perspective
Jakola, Asgeir S; Sagberg, Lisa Millgård; Gulati, Sasha; Solheim, Ole (Peer reviewed; Journal article, 2020)Introduction: Diffuse glioma is a challenging neurosurgical entity. Although surgery does not provide a cure, it may greatly influence survival, brain function, and quality of life. Surgical treatment is by nature highly ... -
Angiogenesis and radiological tumor growth in patients with glioblastoma
Mikkelsen, Vilde Elisabeth; Stensjøen, Anne Line; Granli, Unn Sophie; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole; Torp, Sverre Helge (Journal article; Peer reviewed, 2018)Background The preoperative growth of human glioblastomas (GBMs) has been shown to vary among patients. In animal studies, angiogenesis has been linked to hypoxia and faster growth of GBM, however, its relation to the ... -
Animal study assessing safety of an acoustic coupling fluid that holds the potential to avoid surgically induced artifacts in 3D ultrasound guided operations
Jakola, Asgeir S; Jørgensen, Arve; Selbekk, Tormod; Michler, Ralf-Peter; Solheim, Ole; Torp, Sverre Helge; Sagberg, Lisa Millgård; Aadahl, Petter; Unsgård, Geirmund (Journal article; Peer reviewed, 2014)Background Use of ultrasound in brain tumor surgery is common. The difference in attenuation between brain and isotonic saline may cause artifacts that degrade the ultrasound images, potentially affecting resection grades ... -
Are there predilection sites for intracranial meningioma? A population-based atlas
Hosainey, Sayied Abdol Mohieb; Bouget, David; Reinertsen, Ingerid; Sagberg, Lisa Millgård; Torp, Sverre Helge; Jakola, Asgeir Store; Solheim, Ole (Peer reviewed; Journal article, 2021)Meningioma is the most common benign intracranial tumor and is believed to arise from arachnoid cap cells of arachnoid granulations. We sought to develop a population-based atlas from pre-treatment MRIs to explore the ... -
Assessment of surgery-related morbidity in patients with diffuse gliomas
Sagberg, Lisa Millgård (Doctoral theses at NTNU;2018:327, Doctoral thesis, 2018)The work presented in this thesis focuses on assessment of surgery-related morbidity in patients with diffuse gliomas – the most common primary malignant brain tumour in adults. Diffuse gliomas can be subdivided into ... -
Brain atlas for assessing the impact of tumor location on perioperative quality of life in patients with high-grade glioma: A prospective population-based cohort study
Sagberg, Lisa Millgård; Iversen, Daniel Høyer; Fyllingen, Even Hovig; Jakola, Asgeir Store; Reinertsen, Ingerid; Solheim, Ole (Journal article; Peer reviewed, 2019)Background Tumor location is important for surgical decision making. Particular attention is paid to regions that contain sensorimotor and language functions, but it is unknown if these are the most important regions from ... -
Brain infarctions after glioma surgery: prevalence, radiological characteristics and risk factors
Strand, Per Sveino; Berntsen, Erik Magnus; Fyllingen, Even Hovig; Sagberg, Lisa Millgård; Reinertsen, Ingerid; Gulati, Sasha; Bouget, David; Solheim, Ole (Peer reviewed; Journal article, 2021)Background: Prevalence, radiological characteristics, and risk factors for peritumoral infarctions after glioma surgery are not much studied. In this study, we assessed shape, volume, and prevalence of peritumoral infarctions ... -
Brain infarctions following intracranial tumor surgery - incidence, risk factors, and clinical consequences
Strand, Per Sveino (Doctoral theses at NTNU;2023:164, Doctoral thesis, 2023)Norsk sammendrag Hjernesvulstkirurgi er ein balansegang mellom å fjerne mest mogleg av svulsten samstundes som ein ikkje skadar friskt, kringliggande hjernevev. Komplikasjonar i samband med kirurgi er ikkje til å kome ... -
Children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor in Norway from 1974 through 2013: Unexplainable regional differences in survival
Stensvold, Einar; Myklebust, Tor Åge; Cappelen, Johan; Due-Tønnessen, Bernt Johan; Due-Tønnessen, Paulina; Kepka, Aleksandra; Johannessen, Tom Børge; Krossnes, Bård Kronen; Lundar, Tryggve; Maric, Snezana; Miletic, Hrvoje; Moholdt, Viggo; Myrmel, Kristin Smistad; Nordberg, Terje; Rydland, Jana; Stokland, Tore; Solem, Kristin; Solheim, Ole; Torsvik, Ingrid Kristin; Wikran, Gry Charlotte; Zeller, Bernward; Wesenberg, Finn; Bechensteen, Anne Grete; Brandal, Petter (Peer reviewed; Journal article, 2019)Background: A previous study based on Norwegian Cancer Registry data suggested regional differences in overall survival (OS) after treatment for medulloblastoma (MB) and supratentorial primitive neuroectodermal tumor ... -
Comparative effectiveness of microdecompression and laminectomy for central lumbar spinal stenosis: Study protocol for an observational study
Nerland, Ulf Skule; Jakola, Asgeir Store; Solheim, Ole; Weber, Clemens; Rao, Vidar; Lønne, Greger; Solberg, Tore; Salvesen, Øyvind; Carlsen, Sven Magnus; Nygaard, Øystein Petter; Gulati, Sasha (Journal article; Peer reviewed, 2014)Introduction: This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis. Lumbar spinal ... -
Comparison of contrast in brightness mode and strain ultrasonography of glial brain tumours
Selbekk, Tormod; Brekken, Reidar; Indergaard, Marit Kristina; Solheim, Ole; Unsgård, Geirmund (Journal article; Peer reviewed, 2012)Background Image contrast between normal tissue and brain tumours may sometimes appear to be low in intraoperative ultrasound. Ultrasound imaging of strain is an image modality that has been recently explored for ... -
Development and external validation of a clinical prediction model for functional impairment after intracranial tumor surgery
Staartjes, Victor E.; Broggi, Morgan; Zattra, Costanza Maria; Vasella, Flavio; Velz, Julia; Schiavolin, Silvia; Serra, Carlo; Bartek, Jiri; Fletcher-Sandersjöö, Alexander; Förander, Petter; Kalasauskas, Darius; Renovanz, Mirjam; Ringel, Florian; Brawanski, Konstantin R.; Kerschbaumer, Johannes; Freyschlag, Christian F.; Jakola, Asgeir Store; Sjåvik, Kristin; Solheim, Ole; Schatlo, Bawarjan; Sachkova, Alexandra; Bock, Hans Christoph; Hussein, Abdelhalim; Rohde, Veit; Broekman, Marike L.D.; Nogarede, Claudine O.; Lemmens, Cynthia M.C.; Kernbach, Julius M.; Neuloh, Georg; Bozinov, Oliver; Krayenbühl, Niklaus; Sarnthein, Johannes; Ferroli, Paolo; Regli, Luca; Stienen, Martin N. (Peer reviewed; Journal article, 2021)OBJECTIVE Decision-making for intracranial tumor surgery requires balancing the oncological benefit against the risk for resection-related impairment. Risk estimates are commonly based on subjective experience and generalized ... -
Disulfiram repurposing combined with nutritional copper supplement as add-on to chemotherapy in recurrent glioblastoma (DIRECT): Study protocol for a randomized controlled trial
Jakola, Asgeir S.; Werlenius, Katja; Mudaisi, Munila; Hylin, Sofia; Kinhult, Sara; bartek, Jiri Jr.; Salvesen, Øyvind; Carlsen, Sven Magnus; Strandeus, Michael; Lindskog, Magnus; Lofgren, David; Rydenhaug, Bertil; Carstam, Louise; Gulati, Sasha; Solheim, Ole; Bartek, Jiri; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2018)Background: Disulfiram (DSF) is a well-tolerated, inexpensive, generic drug that has been in use to treat alcoholism since the 1950s. There is now independent preclinical data that supports DSF as an anticancer agent, and ... -
Does preoperative health-related quality of life predict survival in high-grade glioma patients? – a prospective study
Haraldseide, Lisa Marie; Jakola, Asgeir S; Solheim, Ole; Sagberg, Lisa Millgård (Peer reviewed; Journal article, 2019)Purpose: To explore if preoperative patient-reported health-related quality of life (HRQoL) provides additional prognostic value as a supplement to other preoperatively known clinical factors in patients with high-grade ... -
Does risk of brain cancer increase with intracranial volume? A population-based case control study
Fyllingen, Even Hovig; Hansen, Tor Ivar; Jakola, Asgeir Store; Håberg, Asta; Salvesen, Øyvind; Solheim, Ole (Journal article; Peer reviewed, 2018)Background Glioma is the most common primary brain tumor and is believed to arise from glial stem cells. Despite large efforts, there are limited established risk factors. It has been suggested that tissue with more ... -
Effect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial
Hara, Sozaburo; Andresen, Hege; Solheim, Ole; Carlsen, Sven Magnus; Sundstrøm, Terje; Lønne, Greger; Vangen-Lønne, Vetle; Taraldsen, Kristin; Tronvik, Erling Andreas; Øie, Lise Rystad; Gulati, Agnete Malm; Sagberg, Lisa Millgård; Jakola, Asgeir Store; Solberg, Tore; Nygaard, Øystein Petter; Salvesen, Øyvind; Gulati, Sasha (Peer reviewed; Journal article, 2022)Importance: The use of spinal cord stimulation for chronic pain after lumbar spine surgery is increasing, yet rigorous evidence of its efficacy is lacking. Objective: To investigate the efficacy of spinal cord burst ... -
Elevated Serum Lactate in Glioma Patients: Associated Factors
Sitter, Beathe; Forsmark, Annamaria; Solheim, Ole (Peer reviewed; Journal article, 2022)Introduction: Serum lactate levels in brain cancer patients correlate with tumor malignancy grading, and serum lactate has been suggested as a potential biomarker and prognostic factor. The purpose of this study was to ... -
Evaluation of the Scandinavian guidelines for head injuries based on a consecutive series with computed tomography from a Norwegian university hospital
Strand, Ingrid H.; Solheim, Ole; Moen, Kent Gøran; Vik, Anne (Journal article; Peer reviewed, 2012)Background: This study prospectively assesses clinical characteristics and management of consecutive minimal, mild and moderate head injury patients referred for CT scans. Compliance with the Scandinavian head injury guidelines ...