• Simple and robust intravital microscopy procedures in hybrid TIE2GFP-BALB/c transgenic mice 

      Sofias, Alexandros Marios; Åslund, Andreas; Hagen, Nils; Grendstad, Kristin; Hak, Sjoerd (Peer reviewed; Journal article, 2019)
      Purpose The endeavor of deciphering intricate phenomena within the field of molecular medicine dictates the necessity to investigate tumor/disease microenvironment real-time on cellular level. We, hereby, design simple and ...
    • Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking 

      Sofias, Alexandros Marios; Toner, Yohana C.; Meerwaldt, Anu E.; van Leent, Mandy M. T.; Soultanidis, Georgios; Elschot, Mattijs; Gonai, Haruki; Grendstad, Kristin; Flobak, Åsmund; Neckmann, Ulrike; Wolowczyk, Camilla; Fisher, Elizabeth L.; Reiner, Thomas; Davies, Catharina de Lange; Bjørkøy, Geir; Teunissen, Abraham J. P.; Ochando, Jordi; Pérez-Medina, Carlos; Mulder, Willem J. M.; Hak, Sjoerd (Journal article; Peer reviewed, 2020)
      Although the first nanomedicine was clinically approved more than two decades ago, nanoparticles’ (NP) in vivo behavior is complex and the immune system’s role in their application remains elusive. At present, only ...
    • Unraveling the multifaceted in vivo fate of cancer nanomedicine 

      Sofias, Alexandros Marios (Doctoral theses at NTNU;2019:369, Doctoral thesis, 2019)