Browsing NTNU Open by Author "Scheidig, Axel J."

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KDEL Receptor 1 Contributes to Cell Surface Association of Protein Disulfide Isomerases

Bartels, Anne-Kathrin; Gottert, Sascha; Desel, Christine; Schäfer, Miriam; Krossa, Sebastian; Scheidig, Axel J.; Gotzinger, Joachim; Lorenzen, Inken (Journal article; Peer reviewed, 2019)

Background/Aims: Endoplasmic reticulum (ER)-resident proteins with a C-terminal KDEL ER-retention sequence are captured in the Golgi apparatus by KDEL receptors (KDELRs). The binding of such proteins to these receptors ...
Redundancy of protein disulfide isomerases in the catalysis of the inactivating disulfide switch in A Disintegrin and Metalloprotease 17

Krossa, Sebastian; Scheidig, Axel J.; Grötzinger, Joachim; Lorenzen, Inken (Journal article; Peer reviewed, 2018)

A Disintegrin and Metalloprotease 17 (ADAM17) can cause the fast release of growth factors and inflammatory mediators from the cell surface. Its activity has to be turned on which occurs by various stimuli. The active form ...