Blar i NTNU Open på forfatter "Santoni, Giola"
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Antireflux Surgery Versus Antireflux Medication and Risk of Esophageal Adenocarcinoma in Patients With Barrett's Esophagus
Åkerström, Johan Hardvik; Santoni, Giola; von Euler Chelpin, My; Ness-Jensen, Eivind; Kauppila, Joonas H.; Holmberg, Dag; Lagergren, Jesper (Journal article; Peer reviewed, 2023)Background & Aims Antireflux treatment is recommended to reduce esophageal adenocarcinoma in patients with Barrett’s esophagus. Antireflux surgery (fundoplication) counteracts gastroesophageal reflux of all types of ... -
Association Between Metformin Use and Risk of Esophageal Squamous Cell Carcinoma in a Population-Based Cohort Study
Wang, Qiao-Li; Santoni, Giola; Ness-Jensen, Eivind; Lagergren, Jesper; Xie, Shao-Hua (Journal article; Peer reviewed, 2020)4 ABSTRACT ObjectivesEsophageal cancer is a highly fatal malignant neoplasm, with two etiologically different histological types. A large prospective study is expected to elucidate the specific risk of the 90% ... -
Cohort profile: Nordic Helicobacter Pylori eradication project (NordHePEP)
Pettersson, Anna-Klara; Santoni, Giola; Yan, Jacinth; Radkiewicz, Cecilia; Xie, Shaohua; Birgisson, Helgi; Ness-Jensen, Eivind; von Euler-Chelpin, My; Kauppila, Joonas H.; Lagergren, Jesper (Peer reviewed; Journal article, 2022)Purpose This cohort description presents the Nordic Helicobacter Pylori Eradication Project (NordHePEP), a population-based cohort of patients having received eradication treatment for Helicobacter pylori (HP). The ... -
Cohort profile: the Swedish Prescribed Drugs and Health Cohort (SPREDH)
Xie, Shao-Hua; Santoni, Giola; Mattsson, Fredrik; Ness-Jensen, Eivind; Lagergren, Jesper (Journal article; Peer reviewed, 2019)PURPOSE: The Swedish Prescribed Drugs and Health Cohort (SPREDH) is a Swedish population-based cohort based on data from four nationwide health data registers, created with the aim of investigating how the use of selected ... -
Decreased Risk of Esophageal Adenocarcinoma After Gastric Bypass Surgery in a Cohort Study From 3 Nordic Countries
Hardvik Åkerström, Johan; Santoni, Giola; von Euler Chelpin, My; Chidambaram, Swathikan; Markar, Sheraz R.; Maret-Ouda, John; Ness-Jensen, Eivind; Kauppila, Joonas H.; Holmberg, Dag; Lagergren, Jesper (Journal article, 2023)Objective: The objective of this study was to test the hypothesis that bariatric surgery decreases the risk of esophageal and cardia adenocarcinoma. Background: Obesity is strongly associated with esophageal ... -
Development and validation of a risk prediction model for esophageal squamous cell carcinoma using cohort studies
Wang, Qiaoli; Ness-Jensen, Eivind; Santoni, Giola; Xie, Shaohua; Lagergren, Jesper (Peer reviewed; Journal article, 2021)INTRODUCTION: Esophageal squamous cell carcinoma (ESCC) carries a poor prognosis, but earlier tumor detection would improve survival. We aimed to develop and externally validate a risk prediction model based on exposure ... -
Effects of Obesity Surgery on Overall and Disease-Specific Mortality in a 5-Country Population-Based Study
Kauppila, Joonas H.; Tao, Wenjing; Santoni, Giola; von Euler-Chelpin, My; Lynge, Elsebeth; Tryggvadóttir, Laufey; Ness-Jensen, Eivind; Romundstad, Pål Richard; Pukkala, Eero; Lagergren, Jesper (Journal article; Peer reviewed, 2019)Background & Aims Bariatric surgery might reduce overall mortality from obesity. We investigated whether the survival times of patients who have had bariatric surgery are similar to those of the general population and are ... -
Hospital Volume of Antireflux Surgery in Relation to Endoscopic and Surgical Re-interventions
Markar, Sheraz; Santoni, Giola; Maret-Ouda, John; Artama, Miia; Färkkilä, Martti; Lynge, Elsebeth; Pukkala, Eero; Ness-Jensen, Eivind; von Euler-Chelpin, My; Lagergren, Jesper (Journal article; Peer reviewed, 2020)Objective: To test the hypothesis that higher hospital volume decreases endoscopic and surgical re-intervention rates after antireflux surgery. Background: Antireflux surgery for gastro-esophageal reflux disease is ... -
Incidence and mortality in upper gastrointestinal cancer after negative endoscopy for gastroesophageal reflux disease
Holmberg, Dag; Santoni, Giola; von Euler-Chelpin, My; Färkkilä, Martti; Kauppila, Joonas; Maret-Ouda, John; Ness-Jensen, Eivind; Lagergren, Jesper (Peer reviewed; Journal article, 2021)Background and Aims Gastroesophageal reflux disease (GERD) is associated with an increased risk of cancer of the upper gastrointestinal tract. This study aimed to assess whether and to what extent a negative upper endoscopy ... -
Mortality, Reoperation, and Hospital Stay Within 90 Days of Primary and Secondary Antireflux Surgery in a Population-Based Multinational Study
Yanes, Manar; Santoni, Giola; Maret-Ouda, John; Markar, Sheraz; Ness-Jensen, Eivind; Kauppila, Joonas H.; Färkkilä, Martti; Lynge, Elsebeth; Pukkala, Eero; Tryggvadottir, Laufey; von Euler-Chelpin, My; Lagergren, Jesper (Peer reviewed; Journal article, 2021)Background & Aims Absolute rates and risk factors of short-term outcomes after antireflux surgery remain largely unknown. We aimed to clarify absolute risks and risk factors for poor 90-day outcomes of primary laparoscopic ... -
Non-erosive gastro-oesophageal reflux disease and incidence of oesophageal adenocarcinoma in three Nordic countries: population based cohort study
Holmberg, Dag; Santoni, Giola; Euler-Chelpin, My von; Färkkilä, Martti; Kauppila, Joonas H.; Maret-Ouda, John; Ness-Jensen, Eivind; Lagergren, Jesper (Peer reviewed; Journal article, 2023)Objective To assess the incidence rate of oesophageal adenocarcinoma among patients with non-erosive gastro-oesophageal reflux disease compared with the general population. Design Population based cohort study. Setting ... -
Survival after antireflux surgery versus medication in patients with reflux oesophagitis or Barrett's oesophagus: multinational cohort study
Yanes, M.; Santoni, Giola; Maret-Ouda, John; Ness-Jensen, E.; Färkkilä, Martti; Lynge, Elsebeth; Pukkala, Eero; Romundstad, P.; Tryggvadottir, Laufey; -Chelpin, M von Euler; Lagergren, Jesper (Peer reviewed; Journal article, 2021)Background The aim was to examine the hypothesis that antireflux surgery with fundoplication improves long-term survival compared with antireflux medication in patients with reflux oesophagitis or Barrett’s oesophagus. ...