• Assessing the role of genome-wide DNA methylation between smoking and risk of lung cancer using repeated measurements: the HUNT Study 

      Sun, Yi-Qian; Richmond, Rebecca C.; Suderman, Matthew; Min, Josine L; Battram, Thomas; Flatberg, Arnar; Beisvag, Vidar; Nøst, Therese Haugdahl; Guida, Florence; Jiang, Lin; Wahl, Sissel Gyrid Freim; Langhammer, Arnulf; Skorpen, Frank; Walker, Rosie M; Bretherick, Andrew D; Zeng, Yanni; Chen, Yue; Johansson, Mattias; Sandanger, Torkjel M; Relton, Caroline L; Mai, Xiao-Mei (Peer reviewed; Journal article, 2021)
      Background: It is unclear if smoking-related DNA methylation represents a causal pathway between smoking and risk of lung cancer. We sought to identify novel smoking-related DNA methylation sites in blood, with repeated ...
    • Combined Lifestyle Behaviors and the Incidence of Common Cancer Types in the Norwegian Women and Cancer Study (NOWAC) 

      Chen, Sairah Lai Fa; Braaten, Tonje Bjørndal; Borch, Kristin Benjaminsen; Ferrari, Pietro; Sandanger, Torkjel M; Nøst, Therese Haugdahl (Peer reviewed; Journal article, 2021)
      Introduction: Only a small number of studies have examined the impact of combined lifestyle behaviors on cancer incidence, and never in a Norwegian population. Purpose: To examine linear and nonlinear associations of ...
    • Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking 

      Petrovic, Dusan; Bodinier, Barbara; Dagnino, Sonia; Whitaker, Matthew; Karimi, Maryam; Campanella, Gianluca; Nøst, Therese Haugdahl; Polidoro, Silvia; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Lund, Eiliv; Dugué, Pierre-Antoine; Giles, Graham G; Severi, Gianluca; Southey, Melissa; Vineis, Paolo; Stringhini, Silvia; Bochud, Murielle; Sandanger, Torkjel M; Vermeulen, Roel CH; Guida, Florence; Chadeau-Hyam, Marc (Peer reviewed; Journal article, 2022)
      Smoking-related epigenetic changes have been linked to lung cancer, but the contribution of epigenetic alterations unrelated to smoking remains unclear. We sought for a sparse set of CpG sites predicting lung cancer and ...
    • Factors associated with maternal serum levels of perfluoroalkyl substances and organochlorines: A descriptive study of parous women in Norway and Sweden 

      Lauritzen, Hilde Brun; Øien, Torbjørn; Jacobsen, Geir Wenberg; Larose, Tricia L; Odland, Jon Øyvind; van de Bor, Margot; Sandanger, Torkjel M (Journal article; Peer reviewed, 2016)
      Introduction: Perfluoroalkyl substances (PFASs) and organochlorines (OCs) are ubiquitous and persistent in the environment and proposed endocrine disrupting chemicals (EDCs). They can be transferred across the placenta ...
    • Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort 

      Baiju, Nikita; Sandanger, Torkjel M; Sætrom, Pål; Nøst, Therese Haugdahl (Journal article; Peer reviewed, 2021)
      Active smoking has been linked to modulated gene expression in blood. However, there is a need for a more thorough understanding of how quantitative measures of smoking exposure relate to differentially expressed genes ...
    • In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol 

      Larose, Tricia L; Sætrom, Pål; Martinussen, Marit; Skogseth, Haakon; Sandanger, Torkjel M; Scélo, Ghislaine; McHale, Cliona M; Jacobsen, Geir Wenberg; Smith, Martyn T (Journal article; Peer reviewed, 2019)
      Background: The developing fetus is particularly vulnerable to the effects of endocrine disrupting chemicals (EDCs). Molecular fingerprints of EDCs can be identified via microRNA (miRNA) expression profiles and may be ...
    • Maternal serum levels of perfluoroalkyl substances and organochlorines and indices of fetal growth: a Scandinavian case-cohort study 

      Lauritzen, Hilde Brun; Larose, Tricia L; Øien, Torbjørn; Sandanger, Torkjel M; Odland, Jon Øyvind; van de Bor, Margot; Jacobsen, Geir Wenberg (Journal article; Peer reviewed, 2016)
      Background: The associations between prenatal exposure to endocrine disruptive chemicals (EDCs) and fetal growth are inconsistent, and few studies have considered small-for-gestational-age (SGA) birth as an outcome. Our ...
    • Plasma concentrations of persistent organic pollutants and pancreatic cancer risk 

      Porta, Miquel; Gasull, Magda; Pumarega, José; Kiviranta, Hannu; Rantakokko, Panu; Raaschou-Nielsen, Ole; Bergdahl, Ingvar A.; Sandanger, Torkjel M; Agudo, Antoni; Rylander, Charlotta; Nøst, Therese Haugdahl; Donat-Vargas, Carolina; Aune, Dagfinn; Heath, Alicia K; Cirera, Lluís; Goni-Irigoyen, Fernando; Alguacil, Juan; Giménez-Robert, Álex; Tjønneland, Anne; Sund, Malin; Overvad, Kim; Romana Mancini, Francesca; Rebours, Vinciane; Boutron-Ruault, Marie Christine; Kaaks, Rudolf; Schulze, Matthias B.; Trichopoulou, Antonia; Palli, Domenico; Grioni, Sara; Tumino, Rosario; Naccarati, Alessio; Panico, Salvatore; Vermeulen, Roel; Ramón Quirós, J; Rodríguez-Barranco, Miguel; Colorado-Yohar, Sandra M.; Chirlaque, María Dolores; Ardanaz, Eva; Wareham, Nick; Key, Tim; Johansson, Mattias; Murphy, Neil; Ferrari, Pietro; Huybrechts, Inge; Chajes, Veronique; Gonzalez, Carlos Alberto; de Mesquita, Bas Bueno; Gunter, Marc; Vainio, Elisabete Weiderpass; Riboli, Elio; Duell, Eric J; Katzke, Verena; Vineis, Paolo (Peer reviewed; Journal article, 2021)
      Background Findings and limitations of previous studies on persistent organic pollutants (POPs) and pancreatic cancer risk support conducting further research in prospective cohorts. Methods We conducted a prospective ...
    • Prenatal exposure to persistent organic pollutants and child overweight/obesity at 5-year follow-up: a prospective cohort study 

      Lauritzen, Hilde Brun; Larose, Tricia L; Øien, Torbjørn; Sandanger, Torkjel M; Odland, Jon Øyvind; van de Bor, Margot; Jacobsen, Geir Wenberg (Journal article; Peer reviewed, 2018)
      Background Prenatal exposure to persistent organic pollutants (POPs), may influence offspring weight gain. More prospective epidemiological studies are needed to compliment the growing body of evidence from animal ...