Browsing NTNU Open by Author "Sadeghinia, Mohammad Javad"

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Biomechanics of degenerative mitral valve leaflets: Mechanical behavior, collagen structure, and numerical simulations

Sadeghinia, Mohammad Javad (Doctoral theses at NTNU;2023:395, Doctoral thesis, 2023)

Degenerative mitral valve disease impacts around 2% of the population and leads to mitral regurgitation because of valvular incompetence. Two distinct phenotypes of degenerative mitral valve disease are fibroelastic ...
Quantified planar collagen distribution in healthy and degenerative mitral valve: biomechanical and clinical implications

Sadeghinia, Mohammad Javad; Persson, Robert; Ellensen, Vegard Skalstad; Haaverstad, Rune; Holzapfel, Gerhard; Skallerud, Bjørn Helge; Prot, Victorien Emile; Urheim, Stig (Journal article; Peer reviewed, 2024)

Degenerative mitral valve disease is a common valvular disease with two arguably distinct phenotypes: fibroelastic deficiency and Barlow’s disease. These phenotypes significantly alter the microstructures of the leaflets, ...