Browsing NTNU Open by Author "Rossetti, Alessandra"

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ATX-101, a Peptide Targeting PCNA, Has Antitumor Efficacy Alone or in Combination with Radiotherapy in Murine Models of Human Glioblastoma

Gravina, Giovanni Luca; Colapietro, Alessandro; Andrea, Mancini; Rossetti, Alessandra; Martelucci, Stefano; Ventura, Luca; Di Franco, Martina; Marampon, Francesco; Mattei, Vinvenzo; Biordi, Leda Assunta; Otterlei, Marit; Festuccia, Claudio (Peer reviewed; Journal article, 2022)

Cell proliferation requires the orchestrated actions of a myriad of proteins regulating DNA replication, DNA repair and damage tolerance, and cell cycle. Proliferating cell nuclear antigen (PCNA) is a master regulator which ...