Browsing NTNU Open by Author "Rise, Kjersti"
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Cholesterol synthesis pathway genes in prostate cancer are transcriptionally downregulated when tissue confounding is minimized
Rye, Morten Beck; Bertilsson, Helena; Andersen, Maria Karoline; Rise, Kjersti; Bathen, Tone Frost; Drabløs, Finn; Tessem, May-Britt (Journal article; Peer reviewed, 2018)Background The relationship between cholesterol and prostate cancer has been extensively studied for decades, where high levels of cellular cholesterol are generally associated with cancer progression and less favorable ... -
Development of an improved pathway analysis - The FunHop story
Rise, Kjersti (Doctoral theses at NTNU;2022:212, Doctoral thesis, 2022)Norsk sammendrag Arbeidet som presenteres i denne avhandlingen omhandler metabolisme i prostatakreft, hovedsakelig i form av bruk og forbedring av analyse av biologiske spor. En stor del av oppgaven handler om utvikling ... -
FunHoP analysis reveals upregulation of mitochondrial genes in prostate cancer
Rise, Kjersti; Tessem, May-Britt; Drabløs, Finn; Rye, Morten Beck (Peer reviewed; Journal article, 2022)Mitochondrial activity in cancer cells has been central to cancer research since Otto Warburg first published his thesis on the topic in 1956. Although Warburg proposed that oxidative phosphorylation in the tricarboxylic ... -
FunHoP: Enhanced Visualization and Analysis of Functionally Homologous Proteins in Complex Metabolic Networks
Rise, Kjersti; Tessem, May-Britt; Drabløs, Finn; Rye, Morten Beck (Journal article; Peer reviewed, 2021)Cytoscape is often used for visualization and analysis of metabolic pathways. For example, based on KEGG data, a reader for KEGG Markup Language (KGML) is used to load files into Cytoscape. However, although multiple genes ... -
Genome analysis of four novel Psychrobacter spp. and characterisation of their six putative laccase-like multicopper oxidases using bioinformatics tools
Rise, Kjersti (Master thesis, 2015)In May 2009, several Psychrobacter spp. were found at the bottom of the Norwegian sea outside of Svalbard. Four of these, P11F6, P2G3, P11G3 and P11G5, were selected and sequenced for further work, and form the basis for ... -
Integrative metabolic and transcriptomic profiling of prostate cancer tissue containing reactive stroma
Andersen, Maria Karoline; Rise, Kjersti; Giskeødegård, Guro F.; Richardsen, Elin; Bertilsson, Helena; Størkersen, Øystein; Bathen, Tone Frost; Rye, Morten Beck; Tessem, May-Britt (Journal article; Peer reviewed, 2018)Reactive stroma is a tissue feature commonly observed in the tumor microenvironment of prostate cancer and has previously been associated with more aggressive tumors. The aim of this study was to detect differentially ... -
Isolation and genome sequencing of four Arctic marine Psychrobacter strains exhibiting multicopper oxidase activity
Shojaei Moghadam, Morteza; Albersmeier, Andreas; Winkler, Anika; Cimmino, Lorenzo; Rise, Kjersti; Hohmann-Marriott, Martin Frank; Kalinowski, Jörn; Rückert, Christian; Wentzel, Alexander; Lale, Rahmi (Journal article; Peer reviewed, 2016)Background Marine cold-temperature environments are an invaluable source of psychrophilic microbial life for new biodiscoveries. An Arctic marine bacterial strain collection was established consisting of 1448 individual ...