Browsing NTNU Open by Author "Nygaard, Øystein Petter"
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Antibiotic treatment In patients with chronic low back pain and Modic changes (the AIM study): study protocol for a randomised controlled trial.
Storheim, Kjersti; Espeland, Ansgar; Grøvle, Lars; Skouen, Jan Sture; Assmus, Jörg; Anke, Audny; Froholdt, Anne; Pedersen, LM; Haugen, AJ; Fors, Terese; Schistad, Ellina Iordanova; Lutro, Olav; Marchand, Gunn Hege; Kadar, Thomas; Vetti, Nils; Randen, Solfrid; Nygaard, Øystein Petter; Brox, Jens Ivar; Grotle, Margreth; Zwart, JA (Journal article; Peer reviewed, 2017)Background A previous randomised controlled trial (RCT) of patients with chronic low back pain (LBP) and vertebral bone marrow (Modic) changes (MCs) on magnetic resonance imaging (MRI), reported that a 3-month, high-dose ... -
Can we define success criteria for lumbar disc surgery? Estimates for a substantial amount of improvement in core outcome measures
Solberg, Tore; Johnsen, Lars Gunnar; Nygaard, Øystein Petter; Grotle, Margreth (Journal article; Peer reviewed, 2013)Background and purpose A successful outcome after lumbar discectomy indicates a substantial improvement. To use the cutoffs for minimal clinically important difference (MCID) as success criteria has a large potential bias, ... -
Clinical effect modifiers of antibiotic treatment in patients with chronic low back pain and Modic changes - Secondary analyses of a randomised, placebo-controlled trial (the AIM study)
Bråten, Lars Christian Haugli; Grøvle, Lars; Espeland, Ansgar; Pripp, Are Hugo; Grotle, Margreth; Hellum, Christian; Haugen, Anne Julsrud; Froholdt, Anne; Rolfsen, Mads Peder; Nygaard, Øystein Petter; Lutro, Olav; Kristoffersen, Per M; Anke, Audny; Schistad, Ellina Iordanova; Skouen, Jan Sture; Brox, Jens Ivar; Zwart, John-Anker; Storheim, Kjersti (Peer reviewed; Journal article, 2020)Background Randomised trials on antibiotic treatment for patients with chronic low back pain and vertebral endplate changes visible on MRI (Modic changes) have shown mixed results. A possible explanation might be a real ... -
Clinical outcomes after surgery for cervical radiculopathy performed in public and private hospitals : a nationwide relative effectiveness study
Danielsen, Elisabet; Gulati, Sasha; Salvesen, Øyvind Olav; Ingebrigtsen, Tor; Nygaard, Øystein Petter; Solberg, Tore (Peer reviewed; Journal article, 2023)Aims The number of patients undergoing surgery for degenerative cervical radiculopathy has increased. In many countries, public hospitals have limited capacity. This has resulted in long waiting times for elective ... -
Comparative effectiveness of microdecompression and laminectomy for central lumbar spinal stenosis: Study protocol for an observational study
Nerland, Ulf Skule; Jakola, Asgeir Store; Solheim, Ole; Weber, Clemens; Rao, Vidar; Lønne, Greger; Solberg, Tore; Salvesen, Øyvind; Carlsen, Sven Magnus; Nygaard, Øystein Petter; Gulati, Sasha (Journal article; Peer reviewed, 2014)Introduction: This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis. Lumbar spinal ... -
Does Dhulikhel Hospital need a trauma center? : a two month survey
Vannebo, Julia Wilsgaard; Rosseland, Håvard (Master thesis, 2016)Background: Most epidemiologic research in low-income countries tends to focus on diseases, however, one of the leading causes of death is traumatic injuries, especially traumatic brain injury (TBI) and spinal injury. ... -
Effect of Arthroplasty vs Fusion for Patients With Cervical Radiculopathy: A Randomized Clinical Trial
Johansen, Tonje Okkenhaug; Sundseth, Jarle Østberg; Fredriksli, Oddrun; Andresen, Hege; Zwart, John-Anker; Kolstad, Frode; Pripp, Are Hugo; Gulati, Sasha; Nygaard, Øystein Petter (Peer reviewed; Journal article, 2021)Surgical treatment for cervical radiculopathy is increasing. Treatment with motion preserving anterior cervical disc arthroplasty was introduced to prevent symptomatic adjacent segment disease, and there is need to evaluate ... -
Effect of caudal epidural steroid or saline injection in chronic lumbar radiculopathy: multicentre, blinded, randomised controlled trial
Iversen, Trond; Solberg, Tore; Romner, Bertil; Wilsgaard, Tom; Twisk, Jos WR; Anke, Audny; Nygaard, Øystein Petter; Hasvold, Toralf; Ingebrigtsen, Tor (Journal article, 2011)Abstract Objective To assess the efficacy of caudal epidural steroid or saline injection in chronic lumbar radiculopathy in the short (6 weeks), intermediate (12 weeks), and long term (52 weeks). Design Multicentre, ... -
Effect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial
Hara, Sozaburo; Andresen, Hege; Solheim, Ole; Carlsen, Sven Magnus; Sundstrøm, Terje; Lønne, Greger; Vangen-Lønne, Vetle; Taraldsen, Kristin; Tronvik, Erling Andreas; Øie, Lise Rystad; Gulati, Agnete Malm; Sagberg, Lisa Millgård; Jakola, Asgeir Store; Solberg, Tore; Nygaard, Øystein Petter; Salvesen, Øyvind; Gulati, Sasha (Peer reviewed; Journal article, 2022)Importance: The use of spinal cord stimulation for chronic pain after lumbar spine surgery is increasing, yet rigorous evidence of its efficacy is lacking. Objective: To investigate the efficacy of spinal cord burst ... -
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial
Bråten, Lars Christian Haugli; Rolfsen, Mads Peder; Espeland, Ansgar; Wigemyr, Monica; Assmus, Jörg; Froholdt, Anne; Haugen, Anne Julsrud; Marchand, Gunn Hege; Kristoffersen, Per M; Lutro, Olav; Randen, Sigrun; Wilhelmsen, Maja; Winsvold, Bendik K S; Kadar, Thomas; Holmgard, Thor Einar; Vigeland, Maria Dehli; Vetti, Nils; Nygaard, Øystein Petter; Lie, Benedicte Alexandra; Hellum, Christian; Anke, Audny; Grotle, Margreth; Schistad, Ellina Iordanova; Skouen, Jan Sture; Grøvle, Lars; Brox, Jens Ivar; Zwart, John-Anker; Storheim, Kjersti (Journal article; Peer reviewed, 2019)Objective To assess the efficacy of three months of antibiotic treatment compared with placebo in patients with chronic low back pain, previous disc herniation, and vertebral endplate changes (Modic changes). Design Double ... -
Headache and musculoskeletal complaints among subjects with self reported whiplash injury. The HUNT-2 study
Myran, Rigmor; Hagen, Knut; Svebak, Sven; Nygaard, Øystein Petter; Zwart, John-Anker (Journal article; Peer reviewed, 2011)Background: To evaluate the life-time prevalence of self reported whiplash injury and the relationship to chronic musculoskeletal complaints (MSCs) and headache in a large unselected adult population. Methods: Between ... -
Impact of 2015 Earthquakes on a local hospital in Nepal: A Prospective Hospital-based Study
Giri, Samita; Risnes, Kari Ravndal; Uleberg, Oddvar; Rogne, Tormod; Shrestha, Sanu Krishna; Nygaard, Øystein Petter; Koju, Rajendra; Solligård, Erik (Journal article; Peer reviewed, 2018)Introduction Natural disasters pose a great challenge to the health systems and individual health facilities. In low-resource settings, disaster preparedness systems are often limited and not been well described. Two ... -
Impact of the number of previous lumbar operations on patient-reported outcomes after surgery for lumbar spinal stenosis or lumbar disc herniation
Riksaasen, Anniken S.; Kaur, Simran; Solberg, Tore; Austevoll, Ivar Magne; Brox, Jens Ivar; Dolatowski, Filip Celestyn; Hellum, Christian; Kolstad, Frode; Lønne, Greger; Nygaard, Øystein Petter; Ingebrigtsen, Tor (Peer reviewed; Journal article, 2023)Aims Repeated lumbar spine surgery has been associated with inferior clinical outcomes. This study aimed to examine and quantify the impact of this association in a national clinical register cohort. Methods This ... -
Inter-and Intraobserver Agreement of Morphological Grading for Central Lumbar Spinal Stenosis on Magnetic Resonance Imaging
Weber, Clemens; Rao, Vidar; Gulati, Sasha; Kvistad, Kjell Arne; Nygaard, Øystein Petter; Lønne, Greger (Journal article; Peer reviewed, 2015)Study Design Validation study of a morphological grading system for central lumbar spinal stenosis. Objective To evaluate and validate the inter- and intraobserver agreement of a morphological grading system for central ... -
Long-Term Results After Surgery for Degenerative Cervical Myelopathy
Johansen, Tonje Okkenhaug; Holmberg, Siril Therese; Danielsen, Elisabet; Rao, Vidar; Salvesen, Øyvind Olav; Andresen, Hege; Carmen, Vleggeert-Lankamp; Solberg, Tore; Gulati, Sasha; Nygaard, Øystein Petter (Peer reviewed; Journal article, 2023)BACKGROUND AND OBJECTIVES: Degenerative cervical myelopathy (DCM) is a frequent cause of spinal cord dysfunction, and surgical treatment is considered safe and effective. Long-term results after surgery are limited. ... -
Low Back Pain With Persistent Radiculopathy; the Clinical Role of Genetic Variants in the Genes SOX5, CCDC26/GSDMC and DCC
Lie, Marie; Pedersen, Linda Margareth; Heuch, Ingrid; Winsvold, Bendik K S; Gjerstad, Johannes; Hasvik, Eivind Olay; Nygaard, Øystein Petter; Grotle, Margreth; Matre, Dagfinn; Zwart, John Anker Henrik; Nilsen, Kristian Bernhard (Peer reviewed; Journal article, 2022)In a recently published genome-wide association study (GWAS) chronic back pain was associated with three loci; SOX5, CCDC26/GSDMC and DCC. This GWAS was based on a heterogeneous sample of back pain disorders, and it is ... -
A nationwide study of patients operated for cervical degenerative disorders in public and private hospitals
Danielsen, Elisabeth; Mjåset, Christer; Ingebrigtsen, Tor; Gulati, Sasha; Grotle, Margreth; Rudolfsen, Jan Håkon; Nygaard, Øystein Petter; Solberg, Tore (Peer reviewed; Journal article, 2022)During the last decades, there has been an increase in the rate of surgery for degenerative disorders of the cervical spine and in the use of supplementary private health insurance. Still, there is limited knowledge about ... -
Non-respondents do not bias outcome assessment after cervical spine surgery: a multicenter observational study from the Norwegian registry for spine surgery (NORspine)
Ingebrigtsen, Tor; Aune, Grethe; Karlsen, Martine Eriksen; Gulati, Sasha; Kolstad, Frode; Nygaard, Øystein Petter; Thyrhaug, Anette Moltu; Solberg, Tore (Peer reviewed; Journal article, 2022)Background The Norwegian registry for spine surgery (NORspine) is a national clinical quality registry which has recorded more than 10,000 operations for degenerative conditions of the cervical spine since 2012. Registries ... -
The Norwegian registry for spine surgery (NORspine): cohort profile
Mikkelsen, Eirik; Ingebrigtsen, Tor; Thyrhaug, Anette Moltu; Olsen, Lena Ringstad; Nygaard, Øystein Petter; Austevoll, Ivar Magne; Brox, Jens Ivar; Hellum, Christian; Kolstad, Frode; Lønne, Greger; Solberg, Tore (Peer reviewed; Journal article, 2023)Purpose To review and describe the development, methods and cohort of the lumbosacral part of the Norwegian registry for spine surgery (NORspine). Methods NORspine was established in 2007. It is government funded, ... -
Open discectomy vs microdiscectomy for lumbar disc herniation - a protocol for a pragmatic comparative effectiveness study
Sørlie, Andreas; Gulati, Sasha; Giannadakis, Charalampis; Carlsen, Sven Magnus; Salvesen, Øyvind; Nygaard, Øystein Petter; Solberg, Tore (Journal article; Peer reviewed, 2016)Introduction: Since the introduction of lumbar microdiscectomy in the 1970’s, many studies have attempted to compare the effectiveness of this method with that of standard open discectomy with conflicting results. This ...