Browsing NTNU Open by Author "Norvoll Magnussen, Synnøve"

Now showing items 1-3 of 3

    • A Novel Truncated Form of Nephronectin Is Present in Small Extracellular Vesicles Isolated from 66cl4 Cells 

      Toraskar, Jimita Prashant; Norvoll Magnussen, Synnøve; Hagen, Lars; Sharma, Animesh; Hoang, Linh; Bjørkøy, Geir; Svineng, Gunbjørg; Steigedal, Tonje S. (Journal article; Peer reviewed, 2019)
      Extracellular vesicles are emerging as biomarkers in breast cancer. Our recent report suggested that an intracellular granular staining pattern of the extracellular matrix protein nephronectin (NPNT) in breast tumor sections ...

    • Nephronectin as a matrix effector in cancer 

      Norvoll Magnussen, Synnøve; Toraskar, Jimita Prashant; Hadler-Olsen, Elin Synnøve; Steigedal, Tonje S.; Svineng, Gunbjørg (Peer reviewed; Journal article, 2021)
      The extracellular matrix protein nephronectin plays an important regulatory role during embryonic development, controlling renal organogenesis through integrin α8β1 association. Nephronectin has three main domains: five ...

    • Nephronectin promotes breast cancer brain metastatic colonization via its integrin-binding domains 

      Norvoll Magnussen, Synnøve; Toraskar, Jimita Prashant; Wilhelm, Imola; Hasko, Janos; Figenschau, Stine; Molnar, Judit; Seppola, Marit; Steigen, Sonja Eriksson; Steigedal, Tonje S.; Hadler-Olsen, Elin Synnøve; Krizbai, Istvan; Svineng, Gunbjørg (Peer reviewed; Journal article, 2020)
      This study demonstrates a role for the extracellular matrix protein nephronectin (NPNT) in promoting experimental breast cancer brain metastasis, possibly through enhanced binding to- and migration through brain endothelial ...