Browsing NTNU Open by Author "Ness-Jensen, Eivind"
Now showing items 1-20 of 52
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Adherence to clinical guidelines for Barrett’s esophagus
Holmberg, Dag; Ness-Jensen, Eivind; Mattsson, Fredrik; Lagergren, Jesper (Journal article; Peer reviewed, 2019)Background and aim: Clinical guidelines recommend endoscopy surveillance at given intervals or endoscopic therapy for Barrett’s esophagus with low-grade dysplasia (LGD) and high-grade dysplasia (HGD). Whether these guidelines ... -
All-cause and cancer-specific mortality in GORD in a population-based cohort study (the HUNT study)
Ness-Jensen, Eivind; Gottlieb-Vedi, Eivind; Wahlin, Karl; Lagergren, Jesper (Journal article; Peer reviewed, 2018)Objective Gastro-oesophageal reflux is a public health concern which could have associated oesophageal complications, including adenocarcinoma, and possibly also head-and-neck and lung cancers. The aim of this study was ... -
Anthropometry-based obesity phenotypes and risk of colorectal adenocarcinoma: a large prospective cohort study in Norway
Lu, Yunxia; Ness-Jensen, Eivind; Martling, Anna; Hveem, Kristian (Journal article; Peer reviewed, 2016)Background: It is unclear whether obesity phenotypes measured by different anthropometric indices are associated with a risk of colorectal adenocarcinoma by anatomical location. Methods: We compiled harmonized ... -
Antireflux surgery and risk of lung cancer by histological type in a multinational cohort study
Yanes, Manar; Giola, Santoni; Maret-Ouda, John; Ness-Jensen, Eivind; Färkkilä, Martti; Lynge, Elsebeth; Nwaru, Bright I.; Pukkala, Eero; Romundstad, Pål Richard; Tryggvadóttir, Laufey; von Euler-Chelpin, My; Lagergren, Jesper (Peer reviewed; Journal article, 2020)Introduction Airway micro-aspiration might contribute to the proposed associations between gastroesophageal reflux disease (GERD) and some lung diseases, including lung cancer. This study aimed to examine the hypothesis ... -
Assessing the feasibility of targeted screening for esophageal adenocarcinoma based on individual risk assessment in a population-based cohort study in Norway (The HUNT Study)
Xie, Shao-Hua; Ness-Jensen, Eivind; Medefelt, Nils; Lagergren, Jesper (Journal article; Peer reviewed, 2018)OBJECTIVES: Unselected screening for oesophageal adenocarcinoma (OAC) is not justified due to the low absolute risk in the general population. This study aimed to evaluate a risk prediction model in identifying high-risk ... -
Association Between Metformin Use and Risk of Esophageal Squamous Cell Carcinoma in a Population-Based Cohort Study
Wang, Qiao-Li; Santoni, Giola; Ness-Jensen, Eivind; Lagergren, Jesper; Xie, Shao-Hua (Journal article; Peer reviewed, 2020)4 ABSTRACT ObjectivesEsophageal cancer is a highly fatal malignant neoplasm, with two etiologically different histological types. A large prospective study is expected to elucidate the specific risk of the 90% ... -
Cancer Risk After Bariatric Surgery in a Cohort Study from the Five Nordic Countries
Tao, Wenjing; Giola, Santoni; von Euler-Chelpin, My; Ljung, Rickard; Lynge, Elsebeth; Pukkala, Eero; Ness-Jensen, Eivind; Romundstad, Pål Richard; Tryggvadóttir, Laufey; Lagergren, Jesper (Peer reviewed; Journal article, 2020)Purpose Obesity increases the risk of several cancers, but the influence of bariatric surgery on the risk of individual obesity-related cancers is unclear. This study aimed to assess the impact of bariatric surgery on ... -
Changes in prevalence and incidence of gastro-oesophageal reflux symptoms among adults and adolescents, the HUNT study
Visnes, Ellen Sylvia (Master thesis, 2021)Bakgrunn Gastroøsofageal reflukssykdom kjennetegnes av symptomene halsbrann og sure oppstøt. Disse symptomene er svært vanlige i befolkningen, men det er sparsomt med studier som følger forekomsten av symptomene i en ... -
Changes in prevalence, incidence and spontaneous loss of gastro-oesophageal reflux symptoms: a prospective population-based cohort study, the HUNT study
Ness-Jensen, Eivind; Lindam, Anna; Lagergren, Jesper; Hveem, Kristian (Journal article; Peer reviewed, 2012)Objective Changes in the occurrence of gastro-oesophageal reflux symptoms (GORS) in the population remain uncertain. This study aimed to determine the prevalence changes, the incidence and the spontaneous loss of GORS. Design ... -
Circulating Levels of Inflammatory and Metabolic Biomarkers and Risk of Esophageal Adenocarcinoma and Barrett Esophagus: Systematic Review and Meta-analysis
Xie, Shao-hua; Rabbani, Sirus; Ness-Jensen, Eivind; Lagergren, Jesper (Peer reviewed; Journal article, 2020)Associations between circulating levels of obesity-related biomarkers and risk of esophageal adenocarcinoma and Barrett esophagus have been reported, but the results are inconsistent. A literature search until October 2018 ... -
Circulating Sex Hormone Levels and Risk of Esophageal Adenocarcinoma in a Prospective Study in Men
Xie, Shao-Hua; Ness-Jensen, Eivind; Rabbani, Sirus; Langseth, Hilde; Gislefoss, Randi Elin; Mattsson, Fredrik; Lagergren, Jesper (Journal article; Peer reviewed, 2019)OBJECTIVES: Sex hormones have been hypothesized to explain the strong male predominance in esophageal adenocarcinoma, but evidence is needed. This study examined how circulating sex hormone levels influence future risk of ... -
Clinical prediction model for tumor progression in Barrett’s esophagus
Holmberg, Dag; Ness-Jensen, Eivind; Mattsson, Fredrik; Lagergren, Jesper (Journal article; Peer reviewed, 2018)Background Individuals with Barrett’s esophagus (BE) are at increased risk of high-grade dysplasia (HGD) and esophageal adenocarcinoma (EAC), but the cost-effectiveness of general surveillance of BE is low. This study ... -
Cohort profile: the Swedish Prescribed Drugs and Health Cohort (SPREDH)
Xie, Shao-Hua; Santoni, Giola; Mattsson, Fredrik; Ness-Jensen, Eivind; Lagergren, Jesper (Journal article; Peer reviewed, 2019)PURPOSE: The Swedish Prescribed Drugs and Health Cohort (SPREDH) is a Swedish population-based cohort based on data from four nationwide health data registers, created with the aim of investigating how the use of selected ... -
The development and validation of a high-capacity serological assay for celiac disease
Klaasen, Rolf; Warren, David; Iversen, Rasmus; Bolstad, Nils; Andersen, Ina Lervåg; Mjønes, Patricia; Rønne, Elin; Lundin, Knut; Sollid, Ludvig Magne; Ness-Jensen, Eivind (Peer reviewed; Journal article, 2022)Background The aim of the present study was to develop and clinically validate a high-throughput assay for serum IgA and IgG antibodies against transglutaminase-2 (TG2) and to determine appropriate assay cut-offs for ... -
Development and validation of a risk prediction model for esophageal squamous cell carcinoma using cohort studies
Wang, Qiaoli; Ness-Jensen, Eivind; Santoni, Giola; Xie, Shaohua; Lagergren, Jesper (Peer reviewed; Journal article, 2021)INTRODUCTION: Esophageal squamous cell carcinoma (ESCC) carries a poor prognosis, but earlier tumor detection would improve survival. We aimed to develop and externally validate a risk prediction model based on exposure ... -
Effects of Obesity Surgery on Overall and Disease-Specific Mortality in a 5-Country Population-Based Study
Kauppila, Joonas H.; Tao, Wenjing; Santoni, Giola; von Euler-Chelpin, My; Lynge, Elsebeth; Tryggvadóttir, Laufey; Ness-Jensen, Eivind; Romundstad, Pål Richard; Pukkala, Eero; Lagergren, Jesper (Journal article; Peer reviewed, 2019)Background & Aims Bariatric surgery might reduce overall mortality from obesity. We investigated whether the survival times of patients who have had bariatric surgery are similar to those of the general population and are ... -
Endoscopy for Gastroesophageal Reflux Disease and Survival in Esophageal Adenocarcinoma
Holmberg, Dag; Ness-Jensen, Eivind; Mattsson, Fredrik; Lagergren, Jesper (Peer reviewed; Journal article, 2019)Gastroesophageal reflux disease (GERD) is a risk factor of esophageal adenocarcinoma (EAC) and the most common indication for upper gastrointestinal endoscopy. Yet, whether GERD or endoscopy practice influence survival in ... -
Epidemiology of gastro-oesophageal reflux A prospective population-based cohort study: The HUNT study
Ness-Jensen, Eivind (Doktoravhandlinger ved NTNU, 1503-8181; 2014:69, Doctoral thesis, 2014)Introduction Heartburn and acid regurgitation are the characteristic gastro-oesophageal reflux symptoms (GORS). GORS are associated with reduced quality of life and increased risk of oesophageal adenocarcinoma. GORS are ... -
Gastroesophageal Reflux and Sleep Disturbances: A Bidirectional Association in a Population-Based Cohort Study, the HUNT Study
Lindam, Anna; Ness-Jensen, Eivind; Jansson, Catarina; Nordenstedt, Helena; Åkersted, Torbjørn; Hveem, Kristian; Lagergren, Jesper (Journal article; Peer reviewed, 2016)Study Objectives: To investigate the potentially bidirectional association between gastroesophageal reflux symptoms (GERS) and sleep disturbances/ insomnia disorders. Methods: We assessed the incidence of new-onset of ... -
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders
Eijsbouts, Chris; Skogholt, Anne Heidi; Ness-Jensen, Eivind; Hveem, Kristian (Peer reviewed; Journal article, 2021)Irritable bowel syndrome (IBS) results from disordered brain–gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive health questionnaire for ...