Browsing NTNU Open by Author "Ness-Jensen, Eivind"
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Adherence to clinical guidelines for Barrett’s esophagus
Holmberg, Dag; Ness-Jensen, Eivind; Mattsson, Fredrik; Lagergren, Jesper (Journal article; Peer reviewed, 2019)Background and aim: Clinical guidelines recommend endoscopy surveillance at given intervals or endoscopic therapy for Barrett’s esophagus with low-grade dysplasia (LGD) and high-grade dysplasia (HGD). Whether these guidelines ... -
All-cause and cancer-specific mortality in GORD in a population-based cohort study (the HUNT study)
Ness-Jensen, Eivind; Gottlieb-Vedi, Eivind; Wahlin, Karl; Lagergren, Jesper (Journal article; Peer reviewed, 2018)Objective Gastro-oesophageal reflux is a public health concern which could have associated oesophageal complications, including adenocarcinoma, and possibly also head-and-neck and lung cancers. The aim of this study was ... -
Anthropometry-based obesity phenotypes and risk of colorectal adenocarcinoma: a large prospective cohort study in Norway
Lu, Yunxia; Ness-Jensen, Eivind; Martling, Anna; Hveem, Kristian (Journal article; Peer reviewed, 2016)Background: It is unclear whether obesity phenotypes measured by different anthropometric indices are associated with a risk of colorectal adenocarcinoma by anatomical location. Methods: We compiled harmonized ... -
Assessing the feasibility of targeted screening for esophageal adenocarcinoma based on individual risk assessment in a population-based cohort study in Norway (The HUNT Study)
Xie, Shao-Hua; Ness-Jensen, Eivind; Medefelt, Nils; Lagergren, Jesper (Journal article; Peer reviewed, 2018)OBJECTIVES: Unselected screening for oesophageal adenocarcinoma (OAC) is not justified due to the low absolute risk in the general population. This study aimed to evaluate a risk prediction model in identifying high-risk ... -
Association Between Metformin Use and Risk of Esophageal Squamous Cell Carcinoma in a Population-Based Cohort Study
Wang, Qiao-Li; Santoni, Giola; Ness-Jensen, Eivind; Lagergren, Jesper; Xie, Shao-Hua (Journal article; Peer reviewed, 2020)4 ABSTRACT ObjectivesEsophageal cancer is a highly fatal malignant neoplasm, with two etiologically different histological types. A large prospective study is expected to elucidate the specific risk of the 90% ... -
Changes in prevalence, incidence and spontaneous loss of gastro-oesophageal reflux symptoms: a prospective population-based cohort study, the HUNT study
Ness-Jensen, Eivind; Lindam, Anna; Lagergren, Jesper; Hveem, Kristian (Journal article; Peer reviewed, 2012)Objective Changes in the occurrence of gastro-oesophageal reflux symptoms (GORS) in the population remain uncertain. This study aimed to determine the prevalence changes, the incidence and the spontaneous loss of GORS. Design ... -
Circulating Sex Hormone Levels and Risk of Esophageal Adenocarcinoma in a Prospective Study in Men
Xie, Shao-Hua; Ness-Jensen, Eivind; Rabbani, Sirus; Langseth, Hilde; Gislefoss, Randi Elin; Mattsson, Fredrik; Lagergren, Jesper (Journal article; Peer reviewed, 2019)OBJECTIVES: Sex hormones have been hypothesized to explain the strong male predominance in esophageal adenocarcinoma, but evidence is needed. This study examined how circulating sex hormone levels influence future risk of ... -
Clinical prediction model for tumor progression in Barrett’s esophagus
Holmberg, Dag; Ness-Jensen, Eivind; Mattsson, Fredrik; Lagergren, Jesper (Journal article; Peer reviewed, 2018)Background Individuals with Barrett’s esophagus (BE) are at increased risk of high-grade dysplasia (HGD) and esophageal adenocarcinoma (EAC), but the cost-effectiveness of general surveillance of BE is low. This study ... -
Cohort profile: the Swedish Prescribed Drugs and Health Cohort (SPREDH)
Xie, Shao-Hua; Santoni, Giola; Mattsson, Fredrik; Ness-Jensen, Eivind; Lagergren, Jesper (Journal article; Peer reviewed, 2019)PURPOSE: The Swedish Prescribed Drugs and Health Cohort (SPREDH) is a Swedish population-based cohort based on data from four nationwide health data registers, created with the aim of investigating how the use of selected ... -
Effects of Obesity Surgery on Overall and Disease-Specific Mortality in a 5-Country Population-Based Study
Kauppila, Joonas H.; Tao, Wenjing; Santoni, Giola; von Euler-Chelpin, My; Lynge, Elsebeth; Tryggvadóttir, Laufey; Ness-Jensen, Eivind; Romundstad, Pål Richard; Pukkala, Eero; Lagergren, Jesper (Journal article; Peer reviewed, 2019)Background & Aims Bariatric surgery might reduce overall mortality from obesity. We investigated whether the survival times of patients who have had bariatric surgery are similar to those of the general population and are ... -
Endoscopy for Gastroesophageal Reflux Disease and Survival in Esophageal Adenocarcinoma
Holmberg, Dag; Ness-Jensen, Eivind; Mattsson, Fredrik; Lagergren, Jesper (Peer reviewed; Journal article, 2019)Gastroesophageal reflux disease (GERD) is a risk factor of esophageal adenocarcinoma (EAC) and the most common indication for upper gastrointestinal endoscopy. Yet, whether GERD or endoscopy practice influence survival in ... -
Epidemiology of gastro-oesophageal reflux A prospective population-based cohort study: The HUNT study
Ness-Jensen, Eivind (Doktoravhandlinger ved NTNU, 1503-8181; 2014:69, Doctoral thesis, 2014)Introduction Heartburn and acid regurgitation are the characteristic gastro-oesophageal reflux symptoms (GORS). GORS are associated with reduced quality of life and increased risk of oesophageal adenocarcinoma. GORS are ... -
Gastroesophageal Reflux and Sleep Disturbances: A Bidirectional Association in a Population-Based Cohort Study, the HUNT Study
Lindam, Anna; Ness-Jensen, Eivind; Jansson, Catarina; Nordenstedt, Helena; Åkersted, Torbjørn; Hveem, Kristian; Lagergren, Jesper (Journal article; Peer reviewed, 2016)Study Objectives: To investigate the potentially bidirectional association between gastroesophageal reflux symptoms (GERS) and sleep disturbances/ insomnia disorders. Methods: We assessed the incidence of new-onset of ... -
Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci
Tanskanen, Tomas; Van Den Berg, Linda; Välimäki, Niko; Aavikko, Mervi; Ness-Jensen, Eivind; Hveem, Kristian; Wettergren, Yvonne; Lindskog, Elinor Bexe; Tönisson, Neeme; Metspalu, Andres; Silander, Kaisa; Orlando, Giulia; Law, Philip J.; Tuupanen, Sari; Gylfe, Alexandra E.; Hänninen, Ulrika A.; Cajuso, Tatiana; Kondelin, Johanna; Sarin, Antti-Pekka; Pukkala, Eero; Jousilahti, Pekka; Salomaa, Veikko; Ripatti, Samuli; Palotie, Aarno; Järvinen, Heikki; Renkonen-Sinisalo, Laura; Lepistö, Anna; Böhm, Jan; Mecklin, Jukka-Pekka; Al-Tassan, Nada A.; Palles, Claire; Martin, Lynn; Barclay, Ella; Tenesa, Albert; Farrington, Susan M.; Timofeeva, Maria N.; Meyer, Brian F; Wakil, Salma M.; Campbell, Harry; Smith, Christopher G.; Idziaszczyk, Shelley; Maughan, Tim S.; Kaplan, Richard; Kerr, Rachel; Kerr, David; Buchanan, Daniel D.; Win, Aung K.; Hopper, John; Jenkins, Mark A.; Newcomb, Polly A.; Gallinger, Steve; Conti, David; Schumacher, Fredrick R.; Casey, Graham; Cheadle, Jeremy P.; Dunlop, Malcolm G.; Tomlinson, Ian P; Houlston, Richard S.; Palin, Kimmo; Aaltonen, Lauri (Journal article; Peer reviewed, 2018)Genome-wide association studies have been successful in elucidating the genetic basis of colorectal cancer (CRC), but there remains unexplained variability in genetic risk. To identify new risk variants and to confirm ... -
Helicobacter pylori in relation to asthma and allergy modified by abdominal obesity: The HUNT study in Norway
Ness-Jensen, Eivind; Langhammer, Arnulf; Hveem, Kristian; Lu, Yunxia (Journal article; Peer reviewed, 2019)Objective It is unknown whether the decreasing prevalence of H. pylori infections is associated with the increase in obesity and asthma and allergy. In this study, we assessed if obesity plays an intermediate role between ... -
Hospital Volume of Antireflux Surgery in Relation to Endoscopic and Surgical Re-interventions
Markar, Sheraz; Santoni, Giola; Maret-Ouda, John; Artama, Miia; Färkkilä, Martti; Lynge, Elsebeth; Pukkala, Eero; Ness-Jensen, Eivind; von Euler-Chelpin, My; Lagergren, Jesper (Journal article; Peer reviewed, 2020)Objective: To test the hypothesis that higher hospital volume decreases endoscopic and surgical re-intervention rates after antireflux surgery. Background: Antireflux surgery for gastro-esophageal reflux disease is ... -
Lifestyle Intervention in Gastroesophageal Reflux Disease
Ness-Jensen, Eivind; Hveem, Kristian; El-Serag, Hashem; Lagergren, Jesper (Journal article; Peer reviewed, 2016)Background & Aims Gastroesophageal reflux disease (GERD) affects up to 30% of adults in Western populations and is increasing in prevalence. GERD is associated with lifestyle factors, particularly obesity and tobacco ... -
Metabolic predispositions and increased risk of colorectal adenocarcinoma by anatomical location: a large population-based cohort study in Norway
Lu, Yunxia; Ness-Jensen, Eivind; Hveem, Kristian; Martling, Anna (Journal article; Peer reviewed, 2015)Whether different definitions of metabolic syndrome (MetS) are differently associated with colorectal adenocarcinoma (CA) by anatomical location is unclear. A population-based cohort study, the Cohort of Norway (CONOR) ... -
Metabolic syndrome and esophageal and gastric cancer
Lin, Yulan; Ness-Jensen, Eivind; Hveem, Kristian; Lagergren, Jesper; Yunxia, Lu (Journal article; Peer reviewed, 2015)Background The role of the metabolic syndrome in the etiology of esophageal and gastric cancer is unclear. Methods This was a large nationwide cohort study based on data from 11 prospective population-based cohorts ... -
Quality of life and psychological and gastrointestinal symptoms after cholecystectomy, a population-based cohort study
Talseth, Arne; Edna, Tom-Harald; Hveem, Kristian; Lydersen, Stian; Ness-Jensen, Eivind (Journal article; Peer reviewed, 2017)Objective The study aims to examine gastrointestinal symptoms, quality of life and the risk of psychological symptoms after cholecystectomy. Design This is a prospective population-based cohort study based on the ...