Browsing NTNU Open by Author "Nærland, Terje"
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Age of First Walking and Associations with Symptom Severity in Children with Suspected or Diagnosed Autism Spectrum Disorder
Reindal, Lise; Nærland, Terje; Weidle, Bernhard; Lydersen, Stian; Andreassen, Ole Andreas; Sund, Anne Mari (Journal article; Peer reviewed, 2019)Age of first walking (AOW) is reported to be later in autism spectrum disorder (ASD) compared with typical development. However, the relationship between AOW and variations in ASD symptoms across different neurodevelopmental ... -
Atypical event-related potentials revealed during the passive parts of a Go-NoGo task in autism spectrum disorder a case-control study
Høyland, Anne Lise; Nærland, Terje; Engstrøm, Morten; Torske, Tonje; Lydersen, Stian; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2019)Background The core features of autism spectrum disorder (ASD) are easily recognizable in non-structured clinical and real-life situations. The features are often difficult to capture in structured laboratory settings, ... -
Autism spectrum disorder polygenic scores are associated with every day executive function in children admitted for clinical assessment
Torske, Tonje; Nærland, Terje; Bettella, Francesco; Bjella, Thomas; Malt, Eva Albertsen; Høyland, Anne Lise; Stenberg, Nina; Øie, Merete Glenne; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2019)Autism spectrum disorder (ASD) and other neurodevelopmental disorders (NDs) are behaviorally defined disorders with overlapping clinical features that are often associated with higher‐order cognitive dysfunction, particularly ... -
The co-occurrence of motor and language impairments in children evaluated for autism spectrum disorder. An explorative study from Norway.
Reindal, Lise; Nærland, Terje; Sund, Anne Mari; Glimsdal, Birgit Avseth; Andreassen, Ole; Weidle, Bernhard (Peer reviewed; Journal article, 2022)Background Current research suggest that motor and language impairments are common and closely related in infants with autism spectrum disorder (ASD). In older children, less is known about how these impairments are related ... -
Co-occurring motor, language and functional impairments in children evaluated for autism spectrum disorder
Reindal, Lise (Doctoral theses at NTNU;2022:320, Doctoral thesis, 2022)Autism spectrum disorder (ASD), a common neurodevelopmental disorder (NDD), is characterised by the presence of core symptoms sufficiently severe to cause functional impairment but otherwise highly heterogenous. The core ... -
Co-occurring motor, language and functional impairments in children evaluated for autism spectrum disorder
Reindal, Lise (Doctoral theses at NTNU;2022:320, Doctoral thesis, 2022) -
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness
Jensen, Søren Beck; Sheikh, Mashhood Ahmed; Akkouh, Ibrahim Ahmed; Szabo, Attila; O'Connell, Kevin Sean; Lekva, Tove; Engh, John; Agartz, Ingrid; Elvsåshagen, Torbjørn; Ormerod, Monica Bettina E. Greenwood; Weibell, Melissa Anne Elin Authen; Johnsen, Erik; Kroken, Rune Andreas; Melle, Ingrid; Drange, Ole Kristian; Nærland, Terje; Vaaler, Arne; Westlye, Lars Tjelta; Aukrust, Pål; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole; Ueland, Thor (Peer reviewed; Journal article, 2022)Abstract Background and Hypothesis Gut microbiota alterations have been reported in severe mental illness (SMI) but fewer studies have probed for signs of gut barrier disruption and inflammation. We hypothesized that ... -
Event-Related Potentials and Executive Function in Adolescents with Autism Spectrum Disorders; a Case-Control Study
Høyland, Anne Lise (Doctoral theses at NTNU, 2018:356;, Doctoral thesis, 2018)Autism Spectrum Disorder (ASD) is now regarded a neurobiological disorder (NDD) with perturbations of brain development. Even so, the diagnosis is still defined based on behavioral criteria, including developmental history ... -
Event-Related Potentials in a Cued Go-NoGo Task Associated with Executive Functions in Adolescents with Autism Spectrum Disorder; A Case-Control Study
Høyland, Anne Lise; Øgrim, Geir; Lydersen, Stian; Hope, Sigrun; Engstrøm, Morten; Torske, Tonje; Nærland, Terje; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2017)Executive functions are often affected in autism spectrum disorders (ASD). The underlying biology is however not well known. In the DSM-5, ASD is characterized by difficulties in two domains: Social Interaction and Repetitive ... -
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.
Lee, Phil H.; Antilla, Verneri; Won, Hyejung; Bettella, Francesco; Agartz, Ingrid; Dale, Anders; Nærland, Terje; Elvsåshagen, Torbjørn; Ødegaard, Ketil Joachim; Melle, Ingrid; Knudsen, Gun Peggy Strømstad; Le Hellard, Stephanie; Reichborn-Kjennerud, Ted; Smeland, Olav Bjerkehagen; Andreassen, Ole Andreas; Neale, Benjamin M; Kendler, Kenneth S.; Smoller, Jordan W. (Peer reviewed; Journal article, 2019)Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed ... -
Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia A comparison among participants between 2 and 53 years
Hope, Sigrun; Nærland, Terje; Høyland, Anne Lise; Torske, Tonje; Malt, Eva; Abrahamsen, Tore G; Nerhus, Mari; Wedervang-Resell, Kirsten; Lonning, Vera Louise Hiorth; Johannessen, Jarle; Steen, Nils Eiel; Agartz, Ingrid; Stenberg, Nina; Hundhausen, Thomas Eckhard; Mørkrid, Lars; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2020)Recent studies suggest that both high and low levels of vitamin B12 (vitB12) may have negative health impacts. We measured VitB12 in patients with the Neurodevelopmental disorders (ND) (n = 222), comprised of Autism Spectrum ... -
Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation
Szabo, Attila; O'Connell, Kevin Sean; Ueland, Thor; Sheikh, Mashhood Ahmed; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Peer reviewed; Journal article, 2021)Background -Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ... -
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
Andreou, Dimitrios; Steen, Nils Eiel; Jørgensen, Kjetil Nordbø; Smelror, Runar Elle; Wedervang-Resell, Kirsten; Nerland, Stener; Westlye, Lars Tjelta; Nærland, Terje; Myhre, Anne Margrethe; Joa, Inge; Reitan, Solveig Merete Klæbo; Vaaler, Arne; Morken, Gunnar; Bøen, Erlend; Elvsåshagen, Torbjørn; Boye, Birgitte; Malt, Ulrik Fredrik; Aukrust, Pål; Skrede, Silje; Kroken, Rune Andreas; Johnsen, Erik; Djurovic, Srdjan; Andreassen, Ole; Ueland, Thor; Agartz, Ingrid (Peer reviewed; Journal article, 2021)Background Both neurodegenerative and neurodevelopmental abnormalities have been suggested to be part of the etiopathology of severe mental illness (SMI). Neuron-specific enolase (NSE), mainly located in the neuronal ... -
Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample
Johannessen, Tor Jarle; Nærland, Terje; Hope, Sigrun; Torske, Tonje; Høyland, Anne Lise; Strohmaier, Jana; Heiberg, Arvid; Rietschel, Marcella; Djurovic, Srdjan; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2017)Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents’ attitudes is needed to ensure good involvement of caregivers, which is crucial ... -
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Engh, John; Ueland, Thor; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Wedervang-Resell, Kirsten; Weibell, Melissa; Westlye, Lars Tjelta; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole (Peer reviewed; Journal article, 2021)Background Immune dysfunction has been implicated in the pathogenesis of schizophrenia and other nonaffective psychosis (SCZ), bipolar spectrum disorder (BIP) and major depressive disorder (MDD). The cytokines B cell-activating ... -
Sex as a Moderator Between Parent Ratings of Executive Dysfunction and Social Difficulties in Children and Adolescents with Autism Spectrum Disorder
Torske, Tonje; Nærland, Terje; Quintana, Daniel; Hypher, Ruth Elizabeth; Kaale, Anett; Høyland, Anne Lise; Hope, Sigrun; Johannessen, Tor Jarle; Øie, Merete Glenne; Andreassen, Ole (Peer reviewed; Journal article, 2022)Girls and boys might differ in autistic symptoms and associated cognitive difficulties such as executive function (EF). We investigated sex differences in the relationship between parent rated EF and autistic symptoms in ... -
Structural and Pragmatic Language Impairments in Children Evaluated for Autism Spectrum Disorder (ASD)
Reindal, Lise; Nærland, Terje; Weidle, Bernhard; Lydersen, Stian; Andreassen, Ole Andreas; Sund, Anne Mari (Peer reviewed; Journal article, 2021)Pragmatic language impairments are common in neurodevelopmental disorders, especially in autism spectrum disorder (ASD). The relationship between structural language skills and pragmatic competence in children with autistic ... -
Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Sheikh, Mashhood Ahmed; O'Connell, Kevin Sean; Lekva, Tove; Szabo, Attila; Akkouh, Ibrahim Ahmed; Osete, Jordi Requena; Agartz, Ingrid; Engh, John; Andreou, Dimitrios; Boye, Birgitte; Bøen, Erlend; Elvsåshagen, Torbjørn; Hope, Sigrun; Werner, Maren Caroline Frogner; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Melle, Ingrid; Drange, Ole Kristian; Morken, Gunnar; Nærland, Terje; Sørensen, Kjetil; Vaaler, Arne; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Aukrust, Pål; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole; Ueland, Thor (Peer reviewed; Journal article, 2022)Background Cell adhesion molecules (CAMs) orchestrate leukocyte trafficking and could link peripheral and neuroinflammation in patients with severe mental illness (SMI), by promoting inflammatory and immune-mediated ... -
The relation between face-emotion recognition and social function in adolescents with autism spectrum disorders: A case control study
Høyland, Anne Lise; Nærland, Terje; Engstrøm, Morten; Lydersen, Stian; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2017)An altered processing of emotions may contribute to a reduced ability for social interaction and communication in autism spectrum disorder, ASD. We investigated how face-emotion recognition in ASD is different from typically ...