• Alpha-tocopherol and MRI outcomes in multiple sclerosis - association and prediction 

      Løken-Amsrud, Kristin Ingeleiv; Myhr, Kjell-Morten; Bakke, Søren Jacob; Beiske, Antonie Giæver; Bjerve, Kristian S; Bjørnarå, Bård T.; Hovdal, Harald Olav; Lilleås, Finn; Midgard, Rune; Pedersen, Tom; Saltyte Benth, Jurate; Torkildsen, Øivind; Wergeland, Stig; Holmøy, Trygve (Journal article; Peer reviewed, 2013)
      Objective: Alpha-tocopherol is the main vitamin E compound in humans, and has important antioxidative and immunomodulatory properties. The aim of this study was to study alpha-tocopherol concentrations and their relationship ...
    • Cognitive and Emotional Impairment after Minor Stroke and Non-ST-Elevation Myocardial Infarction (NSTEMI): A Prevalence Study 

      Morsund, Åse Hagen; Ellekjær, Hanne; Gramstad, Arne; Reiestad, Magnus Tallaksen; Midgard, Rune; Sando, Sigrid Botne; Jonsbu, Egil; Næss, Halvor (Journal article; Peer reviewed, 2019)
      Aim. To study the prevalence of cognitive and emotional impairment following a minor ischemic stroke compared to an age-matched group with non-ST-elevation myocardial infarction (NSTEMI). Methods. We included patients aged ...
    • Do Patients With Chronic Low Back Pain Benefit From Early Intervention Regarding Absence From Work? A randomized, controlled, single-center pilot study 

      Norbye, Anja M. Davis; Omdal, Aina Vedvik; Nygaard, Marit; Romild, Ulla Kristina; Eldøen, Guttorm; Midgard, Rune (Journal article; Peer reviewed, 2016)
      Study Design. A randomized, controlled, single-center pilot study. Objective. The aim of this study was to investigate the feasibility of running a trial to explore if early intervention in individuals with chronic low ...
    • Do patients with chronic low back pain experience pain reduction and functional improvement after treatment at a multidisciplinary outpatient clinic? 

      Norbye, Anja M. Davis; Nygaard, Marit Eikrem; Omdal, Aina Vedvik; Eldøen, Guttorm; Romild, Ulla Kristina; Midgard, Rune (Journal article; Peer reviewed, 2017)
      Background: Low back pain is the most common affliction of the musculoskeletal system. Patients with chronic low back pain cost the society great expenses in treatments and other social benefits; however, the effects of ...
    • Gut microbiota composition during a 12-week intervention with delayed-release dimethyl fumarate in multiple sclerosis – a pilot trial 

      Storm-Larsen, Christopher; Myhr, Kjell-Morten; Farbu, Elisabeth; Midgard, Rune; Nyquist, Kaja Beate; Broch, Line; Berg-Hansen, Pål; Hov, Johannes Espolin Roksund; Holmøy, Trygve (Journal article; Peer reviewed, 2019)
      Introduction Patients with multiple sclerosis may have a distinct gut microbiota profile. Delayed-release dimethyl fumarate is an orally administered drug for relapsing–remitting multiple sclerosis, which has been ...
    • High incidence and prevalence of MS in Møre and Romsdal County, Norway, 1950–2018 

      Willumsen, Johannes Sverre; Aarseth, Jan Harald; Myhr, Kjell-Morten; Midgard, Rune (Peer reviewed; Journal article, 2020)
      Objective To determine prevalence and longitudinal trends in incidence of MS in Møre and Romsdal County, Western Norway, from 1950 to 2018. Methods Retrospective longitudinal population-based observational study. All ...
    • Inflammation markers in multiple sclerosis: CXCL16 reflects and may also predict disease activity 

      Holmøy, Trygve; Løken-Amsrud, Kristin Ingeleiv; Bakke, Jacob; Beiske, Antonie Giæver; Bjerve, Kristian S; Hovdal, Harald Olav; Lilleås, Finn; Midgard, Rune; Pedersen, Tom; Saltyte Benth, Jurate; Torkildsen, Øivind; Wergeland, Stig; Myhr, Kjell-Morten; Michelsen, Annika; Aukrust, Pål; Ueland, Thor (Journal article; Peer reviewed, 2013)
      Background: Serum markers of inflammation are candidate biomarkers in multiple sclerosis (MS). ω-3 fatty acids are suggested to have anti-inflammatory properties that might be beneficial in MS. We aimed to explore ...
    • Level of education and multiple sclerosis risk over a 50-year period: Registry-based sibling study 

      Bjørnevik, Kjetil; Riise, Trond; Benjaminsen, Espen; Celius, Elisabeth Gulowsen; Dahl, Ole-Petter; Kampman, Margitta Theodora; Løken-Amsrud, Kristin Ingeleiv; Midgard, Rune; Myhr, Kjell-Morten; Torkildsen, Øivind; Vatne, Anita; Grytten, Nina (Journal article; Peer reviewed, 2016)
      Background: The conflicting results from studies on socioeconomic status (SES) and multiple sclerosis (MS) risk might be due to a change in the distribution of environmental exposures over time or to methodological ...
    • No association of tobacco use and disease activity in multiple sclerosis 

      Kvistad, Silje; Myhr, Kjell-Morten; Holmøy, Trygve; Saltyte Benth, Jurate; Løken-Amsrud, Kristin Ingeleiv; Wergeland, Stig; Beiske, Antonie Giæver; Bjerve, Kristian S; Hovdal, Harald Olav; Lilleås, Finn; Midgard, Rune; Pedersen, Tom; Bakke, Søren Jacob; Torkildsen, Øivind (Journal article; Peer reviewed, 2016)
      Objective: To study whether tobacco use is associated with MRI and clinical disease activity in patients with multiple sclerosis (MS). Methods: Prospective cohort study of 87 patients with relapsing-remitting MS originally ...
    • Risk of cancer among multiple sclerosis patients, siblings, and population controls: A prospective cohort study 

      Grytten, Nina; Myhr, Kjell-Morten; Celius, Elisabeth Gulowsen; Benjaminsen, Espen; Kampman, Margitta Theodora; Midgard, Rune; Vatne, Anita; Aarseth, Jan Harald; Riise, Trond; Torkildsen, Øivind (Journal article; Peer reviewed, 2019)
      Background: Risk of cancer in multiple sclerosis (MS) patients compared to their siblings is unknown. Objective: The objective was to prospectively investigate the risk of cancer among MS patients compared to siblings ...
    • Spasticity, gait, and balance in patients with multiple sclerosis: A cross‐sectional study 

      Norbye, Anja M. Davis; Midgard, Rune; Thrane, Gyrd (Journal article; Peer reviewed, 2019)
      Objective More than 80% of people with multiple sclerosis (MS) are affected by spasticity. Spasticity is known to reduce quality of life and contribute to additional symptoms, such as pain and reduced mobility, but the ...
    • The development of cognitive and emotional impairment after a minor stroke: A longitudinal study 

      Morsund, Åse Hagen; Ellekjær, Hanne; Gramstad, Arne; Reiestad, Magnus Tallaksen; Midgard, Rune; Sando, Sigrid Botne; Jonsbu, Egil; Næss, Halvor (Journal article; Peer reviewed, 2019)
      Objectives To study the development of cognitive and emotional symptoms between 3 and 12 months after a minor stroke. Material and Methods We included patients from stroke units at hospitals in the Central Norway Health ...