• 18F-FACBC PET/MRI in diagnostic assessment and neurosurgery of gliomas 

      Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Hong, Yan Dai; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2019)
      Purpose This pilot study aimed to evaluate the amino acid tracer 18F-FACBC with simultaneous PET/MRI in diagnostic assessment and neurosurgery of gliomas. Materials and Methods Eleven patients with suspected primary or ...
    • 18F-FACBC PET/MRI in the evaluation of human brain metastases: a case report 

      Johannessen, Knut; Berntsen, Erik Magnus; Johansen, Håkon; Solheim, Tora S; Karlberg, Anna Maria; Eikenes, Live (Peer reviewed; Journal article, 2021)
      Abstract Background: Patients with metastatic cancer to the brain have a poor prognosis. In clinical practice, MRI is used to delineate, diagnose and plan treatment of brain metastases. However, MRI alone is limited in ...
    • AI-driven attenuation correction for brain PET/MRI: Clinical evaluation of a dementia cohort and importance of the training group size 

      Ladefoged, Claes Nøhr; Hansen, Adam Espe; Henriksen, Otto Mølby; Bruun, Frederik Jager; Eikenes, Live; Øen, Silje Kjærnes; Karlberg, Anna Maria; Højgaard, Liselotte; Law, Ian; Andersen, Flemming Littrup (Peer reviewed; Journal article, 2020)
      Introduction Robust and reliable attenuation correction (AC) is a prerequisite for accurate quantification of activity concentration. In combined PET/MRI, AC is challenged by the lack of bone signal in the MRI from which ...
    • Diagnostic accuracy of anti-3-[18F]-FACBC PET/MRI in gliomas 

      Karlberg, Anna Maria; Pedersen, Lars Kjelsberg; Vindstad, Benedikte Emilie; Skjulsvik, Anne Jarstein; Johansen, Håkon; Solheim, Ole Skeidsvoll; Skogen, Karoline; Kvistad, Kjell Arne; Bogsrud, Trond; Myrmel, Kristin Smistad; Giskeødegård, Guro F.; Ingebrigtsen, Tor; Berntsen, Erik Magnus; Eikenes, Live (Peer reviewed; Journal article, 2023)
      Purpose - The primary aim was to evaluate whether anti-3-[18F]FACBC PET combined with conventional MRI correlated better with histomolecular diagnosis (reference standard) than MRI alone in glioma diagnostics. The ability ...
    • Diagnostic Value of 18F-FACBC PET/MRI in Brain Metastases 

      Øen, Silje Kjærnes; Johannessen, Knut; Pedersen, Lars Kjelsberg; Berntsen, Erik Magnus; Totland, Jon Andre; Johansen, Håkon; Bogsrud, Trond Velde; Solheim, Tora S; Karlberg, Anna Maria; Eikenes, Live (Peer reviewed; Journal article, 2022)
      Purpose The study aims to evaluate whether combined 18F-FACBC PET/MRI could provide additional diagnostic information compared with MRI alone in brain metastases. Patients and Methods Eighteen patients with newly ...
    • Histomolecular Validation of [<sup>18</sup>F]-FACBC in Gliomas Using Image-Localized Biopsies 

      Vindstad, Benedikte Emilie; Skjulsvik, Anne Jarstein; Pedersen, Lars Kjelsberg; Berntsen, Erik Magnus; Solheim, Ole Skeidsvoll; Ingebrigtsen, Tor; Reinertsen, Ingerid; Johansen, Håkon; Eikenes, Live; Karlberg, Anna Maria (Journal article; Peer reviewed, 2024)
      Background: Gliomas have a heterogeneous nature, and identifying the most aggressive parts of the tumor and defining tumor borders are important for histomolecular diagnosis, surgical resection, and radiation therapy ...
    • Hypoxia imaging and theranostic potential of [64Cu][Cu(ATSM)] and ionic Cu(II) salts: a review of current evidence and discussion of the retention mechanisms 

      Liu, Tengzhi; Karlsen, Morten; Karlberg, Anna Maria; Redalen, Kathrine (Peer reviewed; Journal article, 2020)
      Background Tumor hypoxia (low tissue oxygenation) is an adverse condition of the solid tumor environment, associated with malignant progression, radiotherapy resistance, and poor prognosis. One method to detect tumor ...
    • Image Quality and Detectability in Siemens Biograph PET/MRI and PET/CT Systems - A Phantom study 

      Øen, Silje Kjærnes; Aasheim, Lars Birger; Eikenes, Live; Karlberg, Anna Maria (Journal article; Peer reviewed, 2019)
      Background The technology of modern positron emission tomography (PET) systems continuously improving, and with it the possibility to detect smaller lesions. Since first introduced in 2010, the number of hybrid PET/magnetic ...
    • Multimodal 18F-Fluciclovine PET/MRI and Ultrasound-Guided Neurosurgery of an Anaplastic Oligodendroglioma 

      Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Myrthue, Mariane Olesen; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Esmaeili, Morteza; Dai, Hong Yan; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2017)
      Background Structural magnetic resonance imaging (MRI) and histopathologic tissue sampling are routinely performed as part of the diagnostic workup for patients with glioma. Because of the heterogeneous nature of gliomas, ...
    • Predicting Regions of Local Recurrence in Glioblastomas Using Voxel-Based Radiomic Features of Multiparametric Postoperative MRI 

      Cepeda, Santiago; Luppino, Luigi Tommaso; Pérez-Núñez, Angel; Solheim, Ole Skeidsvoll; García-García, Sergio; Velasco-Casares, María; Karlberg, Anna Maria; Eikenes, Live; Sarabia, Rosario; Arrese, Ignacio; Zamora, Tomás; Gonzalez, Pedro; Jiménez-Roldán, Luis; Kuttner, Samuel (Peer reviewed; Journal article, 2023)
      The globally accepted surgical strategy in glioblastomas is removing the enhancing tumor. However, the peritumoral region harbors infiltration areas responsible for future tumor recurrence. This study aimed to evaluate a ...
    • Quantitative and clinical impact of MRI-based attenuation correction methods in[18F]FDG evaluation of dementia 

      Øen, Silje Kjærnes; Keil, Thomas; Berntsen, Erik Magnus; Aanerud, Joel Fredrik; Schwarzlmüller, Thomas; Ladefoged, Claes Nøhr; Karlberg, Anna Maria; Eikenes, Live (Journal article; Peer reviewed, 2019)
      Background Positron emission tomography/magnetic resonance imaging (PET/MRI) is a promising diagnostic imaging tool for the diagnosis of dementia, as PET can add complementary information to the routine imaging examination ...
    • Quantitative comparison of PET performance-Siemens Biograph mCT and mMR 

      Karlberg, Anna Maria; Sæther, Oddbjørn; Eikenes, Live; Goa, Pål Erik (Peer reviewed; Journal article, 2016)
      Background: Integrated clinical whole-body PET/MR systems were introduced in2010. In order to bring this technology into clinical usage, it is of great importance to compare the performance with the well-established PET/CT. ...
    • Stråledoser og strålehygieniske tiltak - en kvalitetssikringsstudie i norsk tannhelsetjeneste 

      Breivik, Tonje Elisabeth; Letrud, Andreas (Bachelor thesis, 2019)
      Introduksjon: I løpet av et liv blir vi utsatt for en rekke typer stråling. Ettersom risikoen er ukjent, og den samlede mengden stråling vi får i løpet av et liv er svært omfattende, bør all stråling, inkludert lavdosestråling ...