Blar i NTNU Open på forfatter "Hollan, Ivana"
-
Antirheumatic therapy is associated with reduced complement activation in rheumatoid arthritis
Nguyen, Thao; Hokstad, Ingrid; Fagerland, Morten; Mollnes, Tom Eirik; Hollan, Ivana; Feinberg, Mark W.; Hjeltnes, Gunnbjørg; Eilertsen, Gro Østli; Mikkelsen, Knut; Agewall, Stefan (Journal article; Peer reviewed, 2022)Background The complement system plays an important role in pathophysiology of cardiovascular disease (CVD), and might be involved in accelerated atherogenesis in rheumatoid arthritis (RA). The role of complement activation ... -
Antirheumatic therapy is not associated with changes in circulating N-terminal pro-brain natriuretic peptide levels in patients with autoimmune arthritis
Nguyen, Thao H.P.; Fagerland, Morten; Deyab, Gia; Hjeltnes, Gunnbjørg; Hollan, Ivana; Feinberg, Mark W.; Eilertsen, Gro Østli; Mikkelsen, Knut; Agewall, Stefan (Journal article; Peer reviewed, 2021)Background: Patients with autoimmune arthritis (AA) are at increased risk for impaired cardiac function and heart failure. This may be partly due to the effect of inflammation in heart function. The impact of antirheumatic ... -
Antirheumatic treatment is associated with reduced serum Syndecan-1 in Rheumatoid Arthritis
Deyab, Gia; Reine, Trine M.; Vuong, Tram Thu; Jenssen, Trond Geir; Hjeltnes, Gunnbjørg; Agewall, Stefan; Mikkelsen, Knut; Førre, Øystein; Fagerland, Morten; Kolset, Svein Olav; Hollan, Ivana (Journal article; Peer reviewed, 2021) -
Complement activation predicts negative outcomes in COVID-19: The experience from Northen Italian patients.
Meroni, Pier Luigi; Croci, Stefania; Lonati, Paola Adele; Pregnolato, Francesca; Spaggiari, Lucia; Besutti, Giulia; Bonacini, Martina; Ferrigno, Ilaria; Rossi, Alessandro; Hetland, Geir; Hollan, Ivana; Cugno, Massimo; Tedesco, Francesco; Borghi, Maria Orietta; Salvarani, Carlo (Peer reviewed; Journal article, 2022)Coronavirus disease 19 (COVID-19) may present as a multi-organ disease with a hyperinflammatory and prothrombotic response (immunothrombosis) in addition to upper and lower airway involvement. Previous data showed that ... -
Deficiency of miR-409-3p improves myocardial neovascularization and function through modulation of DNAJB9/p38 MAPK signaling
Bestepe, Furkan; Fritsche, Colette; Lakhotiya, Kartik; Niosi, Carolyn E.; Ghanem, George F.; Martin, Gregory L.; Pal-Ghosh, Ruma; Becker-Greene, Dakota; Weston, James; Hollan, Ivana; Risnes, Ivar; Rynning, Stein Erik; Solheim, Liv Heidi; Feinberg, Mark W.; Blanton, Robert M.; Icli, Basak (Peer reviewed; Journal article, 2023) -
Differential expression of Vitamin D associated genes in the aorta of coronary artery disease patients with and without rheumatoid arthritis
Oma, Ingvild; Olstad, Ole Kristoffer; Andersen, Jacqueline Kirsti; Lyberg, Torstein; Molberg, Øyvind; Fostad, Ida; Fagerland, Morten; Almdahl, Sven Martin; Rynning, Stein Erik; Yndestad, Arne; Aukrust, Pål; Whist, Jon Elling; Hollan, Ivana (Journal article; Peer reviewed, 2018)Background Vitamin D has an important role in the immune system, and has been linked to rheumatoid arthritis (RA) and coronary artery disease (CAD). The exact mechanisms by which vitamin D is involved in these processes ... -
Effects of Antirheumatic Treatment on Cell Cholesterol Efflux and Loading Capacity of Serum Lipoproteins in Spondylarthropathies
Hokstad, Ingrid; Greco, Daniela; Deyab, Gia; Fagerland, Morten; Agewall, Stefan; Hjeltnes, Gunnbjørg; Zimetti, Francesca; Bernini, Franco; Ronda, Nicoletta; Hollan, Ivana (Peer reviewed; Journal article, 2022)Spondyloarthropathies (SpA) are associated with increased cardiovascular risk. Among possible mechanisms is the dysfunction of serum lipoproteins in regulating cell cholesterol homeostasis. Cholesterol efflux capacity ... -
High-sensitivity cardiac troponin T is associated with disease activity in patients with inflammatory arthritis
Nguyen, Thao; Fagerland, Morten; Hollan, Ivana; Whist, Jon Elling; Feinberg, Mark W.; Agewall, Stefan (Peer reviewed; Journal article, 2023)Objective To investigate whether high-sensitivity cardiac troponin T (hsTnT) correlates to markers of disease activity in inflammatory arthritis (IA), and whether antirheumatic treatment influences hsTnT levels. Methods We ... -
Inflammatory cell infiltrates in the heart of patients with coronary artery disease with and without inflammatory rheumatic disease: A biopsy study
Andersen, Jacqueline Kirsti; Oma, Ingvild; Prayson, Richard A.; Kveldstad, Ingjerd Lien; Almdahl, Sven Martin; Fagerland, Morten; Hollan, Ivana (Peer reviewed; Journal article, 2016)Background The cause of premature cardiovascular disease (CVD) in inflammatory rheumatic diseases (IRDs) has not been fully elucidated. As inflammation may play a role, we wanted to compare the occurrence and extent of ... -
Methotrexate attenuates vascular inflammation through an adenosine- microRNA-dependent pathway
Yang, Dafeng; Haemmig, Stefan; Zhou, Haoyang; Pérez-Cremades, Daniel; Sun, Xinghui; Chen, Lei; Li, Jie; Haneo-Mejia, Jorge; Yang, Tianlun; Hollan, Ivana; Feinberg, Mark W. (Peer reviewed; Journal article, 2021)Endothelial cell (EC) activation is an early hallmark in the pathogenesis of chronic vascular diseases. MicroRNA-181b (Mir181b) is an important anti-inflammatory mediator in the vascular endothelium affecting endotoxemia, ... -
Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases
Shields, Kelly J.; Mollnes, Tom Eirik; Eidet, Jon Roger; Mikkelsen, Knut; Almdahl, Sven Martin; Bottazzi, Barbara; Lyberg, Torstein; Manzi, Susan; Ahearn, Joseph M; Hollan, Ivana (Journal article; Peer reviewed, 2017)Purpose Inflammatory rheumatic diseases (IRD) are associated with accelerated coronary artery disease (CAD), which may result from both systemic and vascular wall inflammation. There are indications that complement may ... -
Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study
Hokstad, Ingrid; Deyab, Gia; Fagerland, Morten; Lyberg, Torstein; Hjeltnes, Gunnbjørg; Førre, Øystein Thorleiv; Agewall, Stefan; Mollnes, Tom Eirik; Hollan, Ivana (Journal article; Peer reviewed, 2019)Background The complement system is involved in pathogenesis of cardiovascular disease, and might play a role in accelerated atherogenesis in spondylarthropathies (SpA). Hence, we examined complement activation in SpA, and ...