Browsing NTNU Open by Author "Hoff, Mari"
Now showing items 1-20 of 57
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Adalimumab reduces hand bone loss in rheumatoid arthritis independent of clinical response: Subanalysis of the PREMIER study
Hoff, Mari; Kvien, Tore Kristian; Kälvesten, Johan; Elden, Aake; Kavanaugh, Arthur; Haugeberg, Glenn (Journal article; Peer reviewed, 2011)Background: Anti-TNF therapy has been shown to reduce radiographic joint damage in rheumatoid arthritis (RA) independent of clinical response. This has previously not been examined for periarticular bone loss, the ... -
Anti-osteoporosis drug use: too little, too much, or just right? The HUNT study, Norway
Hoff, Mari; Skurtveit, Svetlana; Meyer, Haakon E; Langhammer, Arnulf; Søgaard, Anne-Johanne; Syversen, Unni; Skovlund, Eva; Abrahamsen, Bo; Forsmo, Siri; Schei, Berit (Journal article; Peer reviewed, 2018)Summary Use of anti-osteoporotic drugs (AODs) was examined in a Norwegian population 50–85 years. Among them with Fracture Risk Assessment Tool (FRAX) score for major osteoporotic fracture ≥ 20, 25% of the women and 17% ... -
Assessment of the genetic and clinical determinants of hip fracture risk: Genome-wide association and Mendelian randomization study
Nethander, Maria; Coward, Eivind; Reimann, Ene; Grahnemo, Louise; Gabrielsen, Maiken Elvestad; Wibom, Carl; Nelis, Mari; Milani, Lili; Esko, Tõnu; Metspalu, Andres; Mägi, Reedik; Funck-Brentano, Thomas; Hoff, Mari; Langhammer, Arnulf; Pettersson-Kymmer, Ulrika; Hveem, Kristian; Ohlsson, Claes (Peer reviewed; Journal article, 2022)Hip fracture is the clinically most important fracture, but the genetic architecture of hip fracture is unclear. Here, we perform a large-scale hip fracture genome-wide association study meta-analysis and Mendelian ... -
The association between rheumatoid arthritis and reduced estimated cardiorespiratory fitness is mediated by physical symptoms and negative emotions: a cross-sectional study
Houge, Ingrid Sæther; Hoff, Mari; Videm, Vibeke (Peer reviewed; Journal article, 2023)Objectives Persons with rheumatoid arthritis (RA) have lower cardiorespiratory fitness (CRF) than healthy individuals. We sought to identify variables explaining the association between RA status and reduced CRF. Methods RA ... -
An atlas of genetic determinants of forearm fracture
Nethander, Maria; Movérare-Skrtic, Sofia; Kämpe, Anders; Coward, Eivind; Reimann, Ene; Grahnemo, Louise; Borbély, Éva; Helyes, Zsuzsanna; Funck-Brentano, Thomas; Cohen-Solal, Martine; Tuukkanen, Juha; Koskela, Antti; Wu, Jianyao; Li, Lei; Lu, Tianyuan; Gabrielsen, Maiken Elvestad; Mägi, Reedik; Hoff, Mari; Lerner, Ulf H.; Henning, Petra; Ullum, Henrik; Erikstrup, Christian; Brunak, Søren; Ostrowski, Sisse Rye; Langhammer, Arnulf; Tuomi, Tiinamaija; Oddsson, Asmundur; Stefansson, Kari; Pettersson-Kymmer, Ulrika; Pedersen, Ole Birger Vesterager; Styrkarsdottir, Unnur; Mäkitie, Outi; Hveem, Kristian; Richards, J. Brent; Ohlsson, Claes (Journal article; Peer reviewed, 2023)Osteoporotic fracture is among the most common and costly of diseases. While reasonably heritable, its genetic determinants have remained elusive. Forearm fractures are the most common clinically recognized osteoporotic ... -
Bone mineral density in patients with psoriatic arthritis: data from the Nord-Trøndelag Health Study 3
Gulati, Agnete Malm; Hoff, Mari; Salvesen, Øyvind; Dhainaut, Alvilde; Semb, Anne Grete; Kavanaugh, Arthur; Haugeberg, Glenn (Journal article; Peer reviewed, 2017)Background The risk of osteoporosis in patients with psoriatic arthritis (PsA) remains unclear. The aim of this study was to compare bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) in patients ... -
The burden of rheumatoid arthritis - physical fitness, function, and mortality
Houge, Ingrid Sæther (Doctoral theses at NTNU;2023:243, Doctoral thesis, 2023)Patients with rheumatoid arthritis (RA) have higher mortality rates than the general population as well as lower cardiorespiratory fitness. They also have an increased risk of myocardial infarction of similar magnitudes ... -
Cardiorespiratory fitness and mortality in rheumatoid arthritis
Liff, Marthe Halsan (Doctoral theses at NTNU;2022:128, Doctoral thesis, 2022)Background Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that affects synovial joints and internal organs. It affects around 1% of the population, and the disease is associated with increased all-cause ... -
Cardiorespiratory fitness in patients with rheumatoid arthritis is associated with the patient global assessment but not with objective measurements of disease activity
Liff, Marthe Halsan; Hoff, Mari; Fremo, Thomas; Wisløff, Ulrik; Thomas, Ranjeny; Videm, Vibeke (Journal article; Peer reviewed, 2019)Objective Patients with rheumatoid arthritis (RA) suffer from more cardiovascular disease (CVD), and develop cardiovascular risk factors at an earlier age than the general population. Cardiorespiratory fitness (CRF) is an ... -
Cardiovascular Disease and Osteoporosis in Psoriatic Arthritis
Gulati, Agnete Malm (Doctoral theses at NTNU;2018:126, Doctoral thesis, 2018)Psoriatic arthritis (PsA) is an inflammatory joint disease (IJD) associated with psoriasis. The clinical presentation is heterogeneous and may involve the peripheral joints, the axial skeleton and the entheses, as well as ... -
Change in cardiovascular risk factors in patients who develop psoriatic arthritis: longitudinal data from the Nord-Trøndelag Health Study (HUNT)
Gulati, Agnete Malm; Salvesen, Øyvind; Thomsen, Ruth Stoklund; Kavanaugh, Arthur; Semb, Anne Grete; Rollefstad, Silvia Christin Hellerud; Haugeberg, Glenn; Hoff, Mari (Journal article; Peer reviewed, 2018)Objectives The aim of this population-based study was to compare changes in cardiovascular (CV) risk factors over a decade-long period in patients who developed psoriatic arthritis (PsA) and the background population. Methods ... -
Changes in physical activity and basic psychological needs related to mental health among people with physical disability during the Covid-19 pandemic in Norway
Bentzen, Marte; Brurok, Berit; Roeleveld, Karin; Hoff, Mari; Jahnsen, Reidun; Wouda, Matthijs Ferdinand; Baumgart, Julia Kathrin (Peer reviewed; Journal article, 2021)Background: People with a physical disability are more inactive than the general population. Due to the positive effects of physical activity (PA) on physical and mental health, maintaining a physically active lifestyle ... -
Changes of inflammation in patients with psoriatic arthritis after high intensity interval training assessed by ultrasound and MRI, a randomized controlled trial
Thomsen, Ruth Stoklund; Nilsen, Tom Ivar Lund; Haugeberg, Glenn; Sitter, Beathe; Kavanaugh, Arthur; Pedersen, Susanne Juhl; Hoff, Mari (Peer reviewed; Journal article, 2023)Background In psoriatic arthritis (PsA) there is a theoretical risk of increased disease activity related to strenuous physical activity, including exercise. We evaluated the effect of high intensity interval training ... -
Comparison of methods to construct a genetic risk score for prediction of rheumatoid arthritis in the population-based Nord-Trøndelag Health Study, Norway
Rostami, Sina; Hoff, Mari; Brown, Matthew A.; Hveem, Kristian; Videm, Vibeke (Peer reviewed; Journal article, 2020)Objectives: To evaluate selection methods among published single-nucleotide polymorphisms (SNPs) associated with RA to construct predictive genetic risk scores (GRSs) in a population-based setting. Methods: The Nord-Trøndelag ... -
Construction and evaluation of the performance of genetic risk scores for ankylosing spondylitis, rheumatoid arthritis, and myocardial infarction in the Norwegian population-based Nord- Trøndelag Health Study (HUNT)
Rostami, Sina (Doctoral theses at NTNU;2020:176, Doctoral thesis, 2020) -
Contribution of an extensive medication-based comorbidity index (Rx-Risk) in explaining the excess mortality after hip fracture in older Norwegians: a NOREPOS cohort study
Holvik, Kristin; Hjellvik, Vidar; Karlstad, Øystein; Gunnes, Nina; Hoff, Mari; Tell, Grethe Seppola; Meyer, Haakon Eduard (Journal article; Peer reviewed, 2022)Objectives: Patients with hip fracture are typically characterised by extensive comorbidities and excess mortality. Methods that account for a wide range of comorbidities are needed when attempting to identify causal ... -
Cortical hand bone loss in rheumatoid arthritis: Evaluating digital X-ray radiogrammetry as outcome measure of disease activity, response variable to treatment and predictor of bone damage
Hoff, Mari (Doktoravhandlinger ved NTNU, 1503-8181; 2009: 189, Doctoral thesis, 2009) Cortical hand bone loss in rheumatoid arthritis Evaluating digital X-ray radiogrammetry as outcome measure of disease activity, response variable to treatment and predictor of bone damage Background and ... -
Cortical hand bone porosity and its association with distal radius Fracture in middle aged and elderly women
Dhainaut, Alvilde; Hoff, Mari; Syversen, Unni; Haugeberg, Glenn (Journal article; Peer reviewed, 2013)Objective: Reduced bone mineral density (BMD), assessed by Dual Energy X-ray absorptiometry (DXA), is a well-known risk factor for fragility fracture. A large proportion of patients with fracture have only slightly ... -
Dickkopf-1 is associated with periarticular bone loss in patients with rheumatoid arthritis
Grandaunet, Berit Helen Jensen; Syversen, Silje Watterdal; Hoff, Mari; Van der Hejde, Désirée; Haugeberg, Glenn; Kvien, Tore Kristian; Standal, Therese (Journal article; Peer reviewed, 2013-11)Objective: To examine whether cytokines shown to suppress osteoblasts, Dickkopf-1 (DKK1) and hepatocyte growth factor (HGF), are associated with periarticular bone loss in rheumatoid arthritis (RA). Methods: RA patients ... -
Discontinuation rate of sulfasalazine, leflunomide and methotrexate due to adverse events in a real-life setting (NOR-DMARD)
Pawel, Mielnik; Sexton, Joseph; Fagerli, Karen Minde; Bakland, Gunnstein; Hu, Yi; Kristianslund, Eirik; Hoff, Mari; Wierød, Ada; Kvien, Tore Kristian Aaserud (Peer reviewed; Journal article, 2023)Objectives MTX, LEF and SSZ are conventional synthetic DMARDs (csDMARDs) with a well-established role in the treatment of RA. We aimed to estimate and compare the relative risks for adverse events (AEs) and the ...