Blar i NTNU Open på forfatter "Grønnestad, Randi"
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Alteration of hepato-lipidomic homeostasis in A/J mice fed an environmentally relevant PFAS mixture
Khan, Essa Ahsan; Grønnestad, Randi; Krøkje, Aase; Bartosova, Zdenka; Johanson, Silje Modahl; Müller, Mette Helen Bjørge; Arukwe, Augustine Ebeku (Peer reviewed; Journal article, 2023)In the present study, we have investigated liver lipid homeostasis and corresponding changes in transcript and functional product levels in A/J mice exposed to environmental relevant concentration of per- and polyfluoroalkyl ... -
Alteration of neuro-dopamine and steroid hormone homeostasis in wild Bank voles in relation to tissue concentrations of PFAS at a Nordic skiing area
Grønnestad, Randi; Schlenk, Daniel; Krøkje, Åse; Jaspers, Veerle; Jenssen, Bjørn Munro; Coffin, Scott; Bertotto, Luísa Becker; Giroux, Marissa; Lyche, Jan Ludvig; Arukwe, Augustine (Peer reviewed; Journal article, 2020)Perfluoroalkyl substances (PFAS) are contaminants that are applied in a wide range of consumer products, including ski products. The present study investigated the neuro-dopamine (DA) and cellular steroid hormone homeostasis ... -
Effects of a complex contaminant mixture on thyroid hormones in breeding hooded seal mothers and their pups
Grønnestad, Randi; Villanger, Gro Dehli; Polder, Anuschka; Kovacs, Kit M.; Lydersen, Christian; Jenssen, Bjørn Munro; Borgå, Katrine (Journal article; Peer reviewed, 2018)There is a general lack of information on the possible effects of perfluoroalkyl substances (PFASs) on thyroid hormones (THs) in wildlife species. The effects of PFASs, which are known endocrine disruptors, on the TH ... -
Levels, patterns, and biomagnification potential of perfluoroalkyl substances in a terrestrial food chain in a Nordic Skiing Area
Grønnestad, Randi; Vazquez, Berta Perez; Arukwe, Augustine; Jaspers, Veerle; Jenssen, Bjørn Munro; Karimi, Mahin; Lyche, Jan Ludvig; Krøkje, Åse (Journal article; Peer reviewed, 2019)Perfluoroalkyl substances (PFASs) are used in a wide range of consumer products, including ski products, such as ski waxes. However, there is limited knowledge on the release of PFASs from such products into the environment ... -
Maternal transfer of perfluoralkyl substances in hooded seals
Grønnestad, Randi; Villanger, Gro Dehli; Polder, Anuschka; Kovacs, Kit; Lydersen, Christian; Jenssen, Bjørn Munro; Borgå, Katrine (Journal article; Peer reviewed, 2017)The role of milk in the transfer of perfluoroalkyl substances (PFASs) to offspring is not well known in wildlife. Eight PFASs were quantified in plasma and milk in mother–pup pairs of hooded seals (Cystophora cristata) ... -
Occurrence of perfluorinated alkylated substances (PFASs) and evaluation of potential genotoxic effects in small rodents from a skiing area, Granåsen, Norway
Pérez Vázquez, Berta (Master thesis, 2018)The aim of the project is to sample small mammals from Granåsen, a PFAS hotspot area, and compare them to the population of Jonsvatnet, chosen as a reference area. -
Oxidative stress responses in liver of A/J mice fed an environmentally relevant mixture of perfluoroalkyl substances (PFASs)
Kelemen, György Dávid (Master thesis, 2021)Recently, the adverse effects of perfluoroalkyl substances (PFASs), have been in the spotlight of several studies. Besides the known tumour inducing and endocrine disrupting characteristics of these chemicals, there has ... -
Per- and polyfluoroalkyl substances (PFAS) in ski products: Environmental contamination, bioaccumulation and effects in rodents
Grønnestad, Randi (Doctoral theses at NTNU;2021:328, Doctoral thesis, 2021)Per- and polyfluoroalkyl substances (PFAS) are a group of anthropogenic contaminants that are widespread in the environment. Due to the strong persistency and water and lipid repellency, PFAS have been used in a wide range ... -
Prenatal exposure to persistent organic pollutants in Northern Tanzania and their distribution between breast milk, maternal blood, placenta and cord blood
Müller, Mette Helen Bjørge; Polder, Anuschka; Brynhildsrud, Ola Brønstad; Grønnestad, Randi; Karimi, Mahin; Lie, Elisabeth; Manyilizu, Wilbert Bunini; Mdegela, R. H.; Mokiti, Frida; Murtada, M.; Nonga, Hezron Emmanuel; Skaare, J. U.; Solhaug, Anita; Lyche, Jan Ludvig (Journal article; Peer reviewed, 2019)Human exposure to persistent organic pollutants (POPs) begins during pregnancy and may cause adverse health effects in the fetus or later in life. The present study aimed to assess prenatal POPs exposure to Tanzanian infants ...