• A 5700 year-old human genome and oral microbiome from chewed birch pitch 

      Jensen, Theis Zetner Trolle; Niemann, Jonas; Iversen, Katrine Højholt; Fotakis, Anna K.; Gopalakrishnan, Shyam; Vågene, Åshild J; Pedersen, Mikkel Winther; Sinding, Mikkel-Holger S.; Ellegaard, Martin R; Allentoft, Morten E.; Lanigan, Liam T; Taurozzi, Alberto J; Nielsen, Sofie Holtsmark; Dee, Michael W; Mortensen, Martin; Christensen, Mads C; Sørensen, Søren; Collins, Matthew J; Gilbert, Marcus Thomas Pius; Sikora, Martin; Rasmussen, Simon; Schroeder, Hannes (Peer reviewed; Journal article, 2019)
      The rise of ancient genomics has revolutionised our understanding of human prehistory but this work depends on the availability of suitable samples. Here we present a complete ancienthuman genome and oral microbiome sequenced ...
    • An expanded mammal mitogenome dataset from Southeast Asia 

      Salleh, Faezah Mohd; Ramos-Madrigal, Jazmín; Peñaloza, Fernando; Liu, Shanlin; Sinding, Mikkel Holger Strander; Patel, Riddhi P.; Martins, Renata; Lenz, Dorina; Fickel, Jörns; Roos, Christian; Shamsir, Mohd Shahir; Azman, Mohammad Shahfiz; Lim, Burton K.; Rossiter, Stephen J.; Wilting, Andreas; Gilbert, Marcus Thomas Pius (Journal article; Peer reviewed, 2017)
      Southeast (SE) Asia is 1 of the most biodiverse regions in the world, and it holds approximately 20% of all mammal species. Despite this, the majority of SE Asia's genetic diversity is still poorly characterized. The growing ...
    • An ‛Aukward’ tale: a genetic approach to discover the whereabouts of the last Great Auks 

      Thomas, Jessica E; Carvalho, Gary R.; Haile, James; Martin, Michael David; Castruita, Jose A. Samaniego; Niemann, Jonas; Sinding, Mikkel Holger Strander; Sandoval-Velasco, Marcela; Rawlence, Nicolas J.; Fuller, Errol; Fjeldså, Jon; Hofreiter, Michael; Stewart, John R; Gilbert, Marcus Thomas Pius; Knapp, Michael (Journal article; Peer reviewed, 2017)
      One hundred and seventy-three years ago, the last two Great Auks, Pinguinus impennis, ever reliably seen were killed. Their internal organs can be found in the collections of the Natural History Museum of Denmark, but the ...
    • Ancient DNA reveals the timing and persistence of organellar genetic bottlenecks over 3,000 years of sunflower domestication and improvement 

      Wales, Nathan; Akman, Melis; Watson, Ray H B; Sánchez Barreiro, Fatima; Smith, Bruce D; Gremillion, Kristen J; Gilbert, Marcus Thomas Pius; Blackman, Benjamin K (Journal article; Peer reviewed, 2019)
      Here, we report a comprehensive paleogenomic study of archaeological and ethnographic sunflower remains that provides significant new insights into the process of domestication of this important crop. DNA from both ancient ...
    • Ancient DNA suggests modern wolves trace their origin to a Late Pleistocene expansion from Beringia 

      Loog, Liisa; Thalmann, Olaf; Sinding, Mikkel Holger Strander; Schuenemann, Verena J.; Perri, Angela; Germonpré, Mietje; Bocherens, Herve; Witt, Kelsey E.; Samaniego Castruita, José Alfredo; Velasco, Marcela Sandoval; Lundstrøm, Inge K.C.; Wales, Nathan; Sonet, Gontran; Frantz, Laurent; Schroeder, Hannes; Budd, Jane; Jimenez, Elodie-Laure; Fedorov, Sergey; Gasparyan, Boris; Kandel, Andrew W.; Lázničková-Galetová, Martina; Napierala, Hannes; Uerpmann, Hans-Peter; Nikolskiy, Pavel A.; Pavlova, Elena Y.; Pitulko, Vladimir V.; Herzig, Karl-Heinz; Malhi, Ripan S.; Willerslev, Eske; Hansen, Anders J.; Dobney, Keith; Gilbert, Marcus Thomas Pius; Krause, Johannes; Larson, Greger; Eriksson, Anders; Manica, Andrea (Journal article; Peer reviewed, 2019)
      Grey wolves (Canis lupus) are one of the few large terrestrial carnivores that have maintained a wide geographical distribution across the Northern Hemisphere throughout the Pleistocene and Holocene. Recent genetic studies ...
    • Ancient genomes from Iceland reveal the making of a human population 

      Ebenesersdóttir, Sigríður Sunna; Sandoval-Velasco, Marcela; Gunnarsdóttir, Ellen D.; Jagadeesan, Anuradha; Guðmundsdóttir, Valdís B.; Thordardóttir, Elísabet L.; Einarsdóttir, Margrét S.; Moore, Kristjan H. S.; Sigurðsson, Ásgeir; Magnúsdóttir, Droplaug N.; Jónsson, Hákon; Snorradóttir, Steinunn; Hovig, Eivind; Møller, Pål; Kockum, Ingrid; Olsson, Tomas; Alfredsson, Lars; Hansen, Thomas F.; Werge, Thomas; Cavalleri, Gianpiero L.; Gilbert, Edmund; Lalueza-Fox, Carles; Walser III, Joe W.; Kristjánsdóttir, Steinunn; Gopalakrishnan, Shyam; Arnadottir, Lilja; Magnússon, Ólafur Þ.; Gilbert, Marcus Thomas Pius; Stefánsson, Kári; Helgason, Agnar (Journal article; Peer reviewed, 2018)
      Opportunities to directly study the founding of a human population and its subsequent evolutionary history are rare. Using genome sequence data from 27 ancient Icelanders, we demonstrate that they are a combination of ...
    • Ancient RNA from Late Pleistocene permafrost and historical canids shows tissue-specific transcriptome survival 

      Smith, Oliver; Dunshea, Glenn; Sinding, Mikkel-Holger; Fedorov, Sergey; Germonpre, Mietje; Bocherens, Hervé; Gilbert, Marcus Thomas Pius (Journal article; Peer reviewed, 2019)
      While sequencing ancient DNA (aDNA) from archaeological material is now commonplace, very few attempts to sequence ancient transcriptomes have been made, even from typically stable deposition environments such as permafrost. ...
    • Beyond DNA barcoding: The unrealized potential of genome skim data in sample identification 

      Bohmann, Kristine; Mirarab, Siavash; Bafna, Vineet; Gilbert, Marcus Thomas Pius (Peer reviewed; Journal article, 2020)
      Genetic tools are increasingly used to identify and discriminate between species. One key transition in this process was the recognition of the potential of the ca 658bp fragment of the organelle cytochrome c oxidase I ...
    • Bone biodeterioration—The effect of marine and terrestrial depositional environments on early diagenesis and bone bacterial community 

      Eriksen, Anne Marie Høier; Nielsen, Tue Kjærgaard; Matthiesen, Henning; Carøe, Christian; Hansen, Lars Hestbjerg; Gregory, David John; Turner-Walker, Gordon; Collins, Matthew James; Gilbert, Marcus Thomas Pius (Peer reviewed; Journal article, 2020)
      Bacteria play an important role in the degradation of bone material. However, much remains to be learnt about the structure of their communities in degrading bone, and how the depositional environment influences their ...
    • Comparative performance of the BGISEQ-500 vs Illumina HiSeq2500 sequencing platforms for palaeogenomic sequencing 

      Mak, Sarah S.T.; Gopalakrishnan, Shyam; Carøe, Christian; Geng, Chunyu; Liu, Shanlin; Sinding, Mikkel Holger Strander; Kuderna, Lukas FK; Zhang, Wenwei; Fu, Shujin; Vieira, Filipe G.; Germonpre, Mietje; Bocherens, Hervé; Fedorov, Sergey; Petersen, Bent; Sicheritz-Pontén, Thomas; Marques-Bonet, Tomas; Zhang, Guojie; Jiang, Hui; Gilbert, Marcus Thomas Pius (Journal article; Peer reviewed, 2017)
      Ancient DNA research has been revolutionized following development of next-generation sequencing platforms. Although a number of such platforms have been applied to ancient DNA samples, the Illumina series are the dominant ...
    • Darwin's Fancy Revised: An Updated Understanding of the Genomic Constitution of Pigeon Breeds 

      Pacheco, George; Van Grouw, Hein; Shapiro, Michael D.; Gilbert, Marcus Thomas Pius; Vieira, Filipe G. (Peer reviewed; Journal article, 2020)
      Through its long history of artificial selection, the rock pigeon (Columba livia Gmelin 1789) was forged into a large number of domestic breeds. The incredible amount of phenotypic diversity exhibited in these breeds has ...
    • Demographic reconstruction from ancient DNA supports rapid extinction of the Great Auk 

      Thomas, Jessica E; Carvalho, Gary R.; James, Haile; Rawlence, Nicolas J.; Martin, Michael David; Ho, Simon Y.W.; Sigfússon, Arnór; Jósefsson, Vigfús A.; Frederiksen, Morten; Linnebjerg, Jannie F.; Castruita, Jose A. Samaniego; Niemann, Jonas; Sinding, Mikkel-Holger S.; Sandoval-Velasco, Marcela; Soares, André E.R.; Lacy, Robert; Barilaro, Christina; Best, Julia; Brandis, Dirk; Cavallo, Chiara; Elorza, Mikelo; Garrett, Kimball L; Groot, Maaike; Johansson, Friederike; Lifjeld, Jan Terje; Nilson, Göran; Serjeanston, Dale; Sweet, Paul; Fuller, Errol; Hufthammer, Anne Karin; Meldgaard, Morten; Fjeldså, Jon; Shapiro, Beth; Hofreiter, Michael; Gilbert, Marcus Thomas Pius; Knapp, Michael (Journal article; Peer reviewed, 2019)
      The great auk was once abundant and distributed across the North Atlantic. It is now extinct, having been heavily exploited for its eggs, meat, and feathers. We investigated the impact of human hunting on its demise by ...
    • Dense sampling of bird diversity increases power of comparative genomics 

      Feng, Shaohong; Stiller, Josefin; Deng, Yuan; Armstrong, Joel; Fang, Qi; Reeve, Andrew Hart; Xie, Duo; Chen, Guangji; Guo, Chunxue; Faircloth, Brant C.; Petersen, Bent; Wang, Zongji; Zhou, Qi; Diekhans, Mark; Chen, Wanjun; Andreu-Sánchez, Sergio; Margaryan, Ashot; Howard, Jason Travis; Parent, Carole; Pacheco, George; Sinding, Mikkel-Holger S.; Puetz, Lara; Cavill, Emily; Gilbert, Marcus Thomas Pius (Peer reviewed; Journal article, 2020)
      Whole-genome sequencing projects are increasingly populating the tree of life and characterizing biodiversity1,2,3,4. Sparse taxon sampling has previously been proposed to confound phylogenetic inference5, and captures ...
    • Diabetic cats have decreased gut microbial diversity and a lack of butyrate producing bacteria 

      Kieler, Ida Nordang; Osto, Melania; Hugentobler, Leoni; Puetz, Lara; Gilbert, Marcus Thomas Pius; Hansen, Torben; Pedersen, Oluf; Reusch, Claudia E.; Zini, Eric; Lutz, Thomas A.; Bjørnvad, Charlotte Reinhard (Peer reviewed; Journal article, 2019)
      Obesity and inactivity are major risk factors of feline diabetes mellitus (FDM) and human type II diabetes mellitus (T2DM). In recent years, changes in the gut microbiota have been suggested as a contributing factor to ...
    • DNA metabarcoding and spatial modelling link diet diversification with distribution homogeneity in European bats 

      Alberdi, Antton; Razgour, Orly; Aizpurua, Ostaizka; Novella-Fernandez, Roberto; Aihartza, Joxerra; Budinski, Ivana; Garin, Inazio; Ibáñez, Carlos; Izagirre, Eñaut; Rebelo, Hugo; Russo, Danilo; Vlaschenko, Anton; Zhelyazkova, Violeta; Zrncic, Vida; Gilbert, Marcus Thomas Pius (Peer reviewed; Journal article, 2020)
      Inferences of the interactions between species’ ecological niches and spatial distribution have been historically based on simple metrics such as low-resolution dietary breadth and range size, which might have impeded the ...
    • DNA-Based Arthropod Diversity Assessment in Amazonian Iron Mine Lands Show Ecological Succession Towards Undisturbed Reference Sites 

      Lynggaard, Christina; Yu, Douglas W.; Oliveira, Guilherme; Caldeira, Cecilio F.; Ramos, Silvio J.; Ellegaard, Martin; Gilbert, Marcus Thomas Pius; Gastauer, Markus; Bohmann, Kristine (Peer reviewed; Journal article, 2020)
      Human activities change natural landscapes, and in doing so endanger biodiversity and associated ecosystem services. To reduce the net impacts of these activities, such as mining, disturbed areas are rehabilitated and ...
    • Early Pleistocene enamel proteome from Dmanisi resolves Stephanorhinus phylogeny 

      Cappellini, Enrico; Welker, Frido; Pandolfi, Luca; Ramos-Madrigal, Jazmín; Samodova, Diana; Rüther, Patrick L.; Fotakis, Anna K.; Lyon, David; Moreno-Mayar, J. Víctor; Bukhsianidze, Maia; Jersie-Christensen, Rosa Rakownikow; Mackie, Meaghan; Ginolhac, Aurélien; Ferring, Reid; Tappen, Martha; Palkopoulou, Eleftheria; Dickinson, Marc R.; Stafford, Jr., Thomas W.; Chan, Yvonne L.; Götherström, Anders; Nathan, Senthilvel K.S.S.; Heintzman, Peter D.; Kapp, Joshua D.; Kirillova, Irina V.; Moodley, Yoshan; Agusti, Jordi; Kahlke, Ralf-Dietrich; Kiladze, Gocha; Martínez-Navarro, Bienvenido; Liu, Shanlin; Sandoval Velasco, Marcela; Sinding, Mikkel-Holger S.; Kelstrup, Christian D.; Allentoft, Morten E.; Orlando, Ludovic; Penkman, Kirsty; Shapiro, Beth; Rook, Lorenzo; Dalén, Love; Gilbert, Marcus Thomas Pius; Olsen, Jesper V.; Lordkipanidze, David; Willerslev, Eske (Journal article; Peer reviewed, 2019)
      The sequencing of ancient DNA has enabled the reconstruction of speciation, migration and admixture events for extinct taxa1. However, the irreversible post-mortem degradation2 of ancient DNA has so far limited its ...
    • Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet 

      Gelabert, Pere; Sandoval-Velasco, Marcela; Serres, Aitor; de Manuel, Marc; Renom, Pere; Margaryan, Ashot; Stiller, Josefin; De-Dios, Toni; Fang, Qi; Feng, Shaohong; Mañosa, Santi; Pacheco, George; Ferrando-Bernal, Manuel; Shi, Guolin; Hao, Fei; Chen, Xianqing; Petersen, Bent; Olsen, Remi-André; Navarro, Arcadi; Deng, Yuan; Dalén, Love; Marques-Bonet, Tomas; Zhang, Guojie; Antunes, Agostinho; Gilbert, Marcus Thomas Pius; Lalueza-Fox, Carles (Peer reviewed; Journal article, 2020)
      As the only endemic neotropical parrot to have recently lived in the northern hemisphere, the Carolina parakeet (Conuropsis carolinensis) was an iconic North American bird. The last surviving specimen died in the Cincinnati ...
    • Functional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features 

      Seki, Ryohei; Li, Caí; Fang, Qi; Hayashi, Shinichi; Egawa, Shiro; Hu, Jiang; Xu, Luohao; Pan, Hailin; Kondo, Mao; Sato, Tomohiko; Matsubara, Haruka; Kamiyama, Namiko; Kitajima, Keiichi; Saito, Daisuke; Liu, Yang; Gilbert, Marcus Thomas Pius; Zhou, Qi; Xu, Xing; Shiroishi, Toshihiko; Irie, Naoki; Tamura, Koji; Zhang, Guojie (Journal article; Peer reviewed, 2017)
      Unlike microevolutionary processes, little is known about the genetic basis of macroevolutionary processes. One of these magnificent examples is the transition from non-avian dinosaurs to birds that has created numerous ...
    • Genetic affinities of an eradicated european plasmodium falciparum strain 

      De-Dios, Toni; van Dorp, Lucy; Gelabert, Pere; Carøe, Christian; Sandoval-Velasco, Marcela; Fregel, Rosa; Escosa, Raül; Aranda, Carles; Huijben, Silvie; Balloux, Francois; Gilbert, Marcus Thomas Pius; Lalueza-Fox, Carles (Journal article; Peer reviewed, 2019)
      Malaria was present in most of Europe until the second half of the 20th century, when it was eradicated through a combination of increased surveillance and mosquito control strategies, together with cross-border and political ...