Browsing NTNU Open by Author "Fraser, Abigail"
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Association of Conventional Cardiovascular Risk Factors With Cardiovascular Disease After Hypertensive Disorders of Pregnancy: Analysis of the Nord-Trøndelag Health Study
Haug, Eirin Beate; Horn, Julie; Markovitz, Amanda R; Fraser, Abigail; Klykken, Bjørnar E.; Dalen, Håvard; Vatten, Lars Johan; Romundstad, Pål Richard; Rich-Edwards, Janet W.; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2019)Importance Women with a history of hypertensive disorders of pregnancy (HDP) have higher risk of cardiovascular disease (CVD). It is not known how much of the excess CVD risk in women with a history of HDP is associated ... -
Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
Hernaez Camba, Alvaro; Rogne, Tormod; Skåra, Karoline Hansen; Håberg, Siri Eldevik; Page, Christian Magnus; Fraser, Abigail; Burgess, Stephen; Lawlor, Deborah A.; Magnus, Maria Christine (Peer reviewed; Journal article, 2021)STUDY QUESTION What is the association between BMI and subfertility? SUMMARY ANSWER We observed a J-shaped relationship between BMI and subfertility in both sexes, when using both a standard multivariable regression ... -
Cardiovascular disease risk factors and infertility: multivariable analyses and one-sample Mendelian randomization analyses in the Trøndelag Health Study
Skåra, Karoline Hansen; Hernaez Camba, Alvaro; Næss, Øyvind Erik; Fraser, Abigail; Lawlor, Deborah A.; Burgess, Stephen; Brumpton, Ben Michael; Magnus, Maria Christine (Journal article; Peer reviewed, 2024)STUDY QUESTION: Are cardiovascular disease (CVD) risk factors causally associated with higher risk of infertility among women and men? SUMMARY ANSWER: We found evidence to support a causal relationship between smoking ... -
Does pregnancy alter life-course lipid trajectories? Evidence from the HUNT Study in Norway.
Markovitz, Amanda Rose; Haug, Eirin Beate; Horn, Julie; Fraser, Abigail; Macdonald-Wallis, Corrie; Tilling, Kate; Rimm, Eric B; Missmer, Stacey A.; Williams, Paige; Romundstad, Pål Richard; Åsvold, Bjørn Olav; Rich-Edwards, Janet Wilson (Journal article; Peer reviewed, 2018)We examined the association between pregnancy and life-course lipid trajectories. Linked data from the Nord-Trøndelag Health Study and the Medical Birth Registry of Norway yielded 19,987 parous and 1,625 nulliparous women. ... -
Does pregnancy complication history improve cardiovascular disease risk prediction? Findings from the HUNT study in Norway.
Markovitz, Amanda Rose; Stuart, Jennifer J.; Horn, Julie; Williams, Paige; Rimm, Eric B; Missmer, Stacey A.; Tanz, Lauren J.; Haug, Eirin Beate; Fraser, Abigail; Timpka, Simon; Klykken, Bjørnar E.; Dalen, Håvard; Romundstad, Pål Richard; Rich-Edwards, Janet W.; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2018)To evaluate whether history of pregnancy complications [pre-eclampsia, gestational hypertension, preterm delivery, or small for gestational age (SGA)] improves risk prediction for cardiovascular disease (CVD). Methods and ... -
Hypertension in Pregnancy and Offspring Cardiovascular Risk in Young Adulthood: Prospective and Sibling Studies in the HUNT Study (Nord-Trøndelag Health Study) in Norway
Alsnes, Ingvild Vatten; Vatten, Lars Johan; Fraser, Abigail; Bjørngaard, Johan Håkon; Rich-Edwards, Janet Wilson; Romundstad, Pål Richard; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2017)Women with hypertensive disorders in pregnancy are at increased lifetime risk for cardiovascular disease. We examined the offspring’s cardiovascular risk profile in young adulthood and their siblings’ cardiovascular risk ... -
Life Course Trajectories of Cardiovascular Risk Factors in Women With and Without Hypertensive Disorders in First Pregnancy: The HUNT Study in Norway
Haug, Eirin; Horn, Julie; Markovitz, Amanda Rose; Fraser, Abigail; Vatten, Lars Johan; Macdonald-Wallis, Corrie; Tilling, Kate; Romundstad, Pål Richard; Rich-Edwards, Janet Wilson; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2018)Background: Women with hypertensive pregnancy disorders have adverse levels of cardiovascular risk factors. It is unclear how this adverse risk factor profile evolves during adult life. We compared life course trajectories ... -
Life course trajectories of Maternal Cardiovascular Risk Factors according to Offspring Birthweight: The HUNT Study
Horn, Julie; Haug, Eirin Beate; Markovitz, Amanda R; Fraser, Abigail; Vatten, Lars Johan; Romundstad, Pål Richard; Rich-Edwards, Janet W.; Åsvold, Bjørn Olav (Peer reviewed; Journal article, 2020)Women with small or large for gestational age offspring are at increased risk of cardiovascular disease later in life. How their cardiovascular risk factors develop across the life course is incompletely known. We linked ... -
Risk of cardiovascular disease in women and men with subfertility: the Trøndelag Health Study
Skåra, Karoline Hansen; Åsvold, Bjørn Olav; Hernaez Camba, Alvaro; Fraser, Abigail; Rich-Edwards, Janet Wilson; Farland, Leslie V.; Næss, Øyvind Erik; Lawlor, Deborah A.; Brumpton, Ben Michael; Magnus, Maria Christine (Peer reviewed; Journal article, 2022)Objective To investigate the association between subfertility and risk of cardiovascular disease (CVD) outcomes. Design Prospective study. Setting Population-based cohort. Patient(s) We studied 31,629 women ... -
Smoking and infertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
Hernáez, Álvaro; Wootton, Robyn E; Page, Christian Magnus; Skåra, Karoline Hansen; Fraser, Abigail; Rogne, Tormod; Magnus, Per Minor; Njølstad, Pål Rasmus; Andreassen, Ole; Burgess, Stephen; Lawlor, Deborah A.; Magnus, Maria Christine (Peer reviewed; Journal article, 2022)Objective: To investigate the association between smoking and infertility. Design: Prospective study. Setting: Nationwide cohort. Patients: 28,606 women and 27,096 men with questionnaire and genotype information from ... -
Ten-Year Cardiovascular Disease Risk Trajectories by Obstetric History: A Longitudinal Study in the Norwegian HUNT Study
Fraser, Abigail; Markovitz, Amanda R.; Haug, Eirin Beate; Horn, Julie; Romundstad, Pål Richard; Dalen, Håvard; Rich-Edwards, Janet Wilson; Åsvold, Bjørn Olav (Peer reviewed; Journal article, 2022)Background Women with a history of obstetric complications are at increased risk of cardiovascular disease, but whether they should be specifically targeted for cardiovascular disease (CVD) risk screening is unknown. Methods ... -
The impact of parity on life course blood pressure trajectories: the HUNT study in Norway
Haug, Eirin; Horn, Julie; Markovitz, Amanda Rose; Fraser, Abigail; Macdonald-Wallis, Corrie; Tilling, Kate; Romundstad, Pål Richard; Rich-Edwards, Janet Wilson; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2018)The drop in blood pressure during pregnancy may persist postpartum, but the impact of pregnancy on blood pressure across the life course is not known. In this study we examined blood pressure trajectories for women in the ... -
The value of pregnancy complication history for 10-year cardiovascular disease risk prediction in middle-aged women
Timpka, Simon; Fraser, Abigail; Schyman, Tommy; Stuart, Jennifer J.; Åsvold, Bjørn Olav; Mogren, Ingrid; Franks, Paul W.; Rich-Edwards, Janet Wilson (Journal article; Peer reviewed, 2018)Women with a history of hypertensive disorders of pregnancy (HDP; preeclampsia and gestational hypertension) or delivering low birth weight offspring (LBW; < 2500 g) have twice the risk of cardiovascular disease (CVD). We ...