Browsing NTNU Open by Author "Farup, Per Grønaas"

A conservative weight loss intervention relieves bowel symptoms in morbidly obese subjects with irritable bowel syndrome: a prospective cohort study

Aasbrenn, Martin; Lydersen, Stian; Farup, Per Grønaas (Journal article; Peer reviewed, 2018)

Background. Irritable bowel syndrome (IBS) is common in subjects with morbid obesity; the effect of weight loss programs on bowel symptoms is largely unknown. Methods. This prospective cohort study explored bowel symptoms, ...

Anti-Saccharomyces cerevisae antibodies (ASCA) are associated with body fat mass and systemic inflammation, but not with dietary yeast consumption: a cross-sectional study

Kvehaugen, Anne Stine; Aasbrenn, Martin; Farup, Per Grønaas (Journal article; Peer reviewed, 2017)

Baker’s/brewer’s yeast, Saccharomyces cerevisiae, has been used as an alternative to antibiotic growth promoters to improve growth performance in animals. In humans, Saccharomyces cerevisiae is among the most commonly ...

APOE Polymorphism and Endocrine Functions in Subjects with Morbid Obesity Undergoing Bariatric Surgery

Farup, Per Grønaas; Jansen, Aina; Hestad, Knut; Aaseth, Jan; Rootwelt, Helge (Peer reviewed; Journal article, 2022)

Background: Obesity is an interplay between genes and the environment, including lifestyle. The genetics of obesity is insufficiently understood. Apolipoprotein E (APOE) genetic polymorphism has been associated with a wide ...

APOE Polymorphism Is Associated with Changes in the Kynurenine Pathway

Farup, Per Grønaas; Rootwelt, Helge; Hestad, Knut (Peer reviewed; Journal article, 2023)

Abstract: Background: APOE polymorphism and the Kynurenine pathway (KP) are associated with many disorders, but little is known about associations between APOE polymorphism and the KP. This study explored the associations ...

APOE – a genetic marker of comorbidity in subjects with morbid obesity

Farup, Per Grønaas; Rootwelt, Helge; Hestad, Knut (Peer reviewed; Journal article, 2020)

Background In population-based studies, the genetic variability of the APOE E alleles have been associated with health outcomes. Health problems are common in subjects with obesity. This study explored associations ...

Are faecal microbiota analyses on species-level suitable clinical biomarkers? A pilot study in subjects with morbid obesity

Farup, Per Grønaas; Maseng, Maria G. (Journal article; Peer reviewed, 2021)

Background: An abnormal faecal microbiota could be a causal factor for disease. This study evaluated a new method for faecal microbiota analysis in subjects with obesity and irritable bowel syndrome. Methods: The study had ...

Are Nonnutritive Sweeteners Obesogenic? Associations between Diet, Faecal Microbiota, and Short-Chain Fatty Acids in Morbidly Obese Subjects

Farup, Per Grønaas; Lydersen, Stian; Valeur, Jørgen (Journal article; Peer reviewed, 2019)

Obesity has been associated with changes in the gut microbiota and its metabolites. The study explored changes in the faecal microbiota and short-chain fatty acids (SCFA) associated with the diet (including nonnutritive ...

Changes in C-reactive protein, neopterin and lactoferrin differ after conservative and surgical weight loss in individuals with morbid obesity

Aasbrenn, Martin; Farup, Per Grønaas; Videm, Vibeke (Journal article; Peer reviewed, 2019)

C-reactive protein, neopterin and lactoferrin are biomarkers of atherosclerotic disease. We aimed to assess changes in these biomarkers after conservative and surgical weight loss interventions in individuals with morbid ...

Changes in circulating sirtuin 1 after bariatric surgery

Opstad, Trine Baur; Farup, Per Grønaas; Rootwelt, Helge; Aaseth, Jan (Peer reviewed; Journal article, 2022)

Background and aims Obesity is associated with chronic inflammation and oxidative stress. Weight loss after bariatric surgery improves the inflammatory state and risk of cardiovascular disease. Improvement in metabolic ...

Changes in Faecal Short-Chain Fatty Acids after Weight-Loss Interventions in Subjects with Morbid Obesity

Farup, Per Grønaas; Valeur, Jørgen (Peer reviewed; Journal article, 2020)

The gut microbiota and their metabolites, e.g., short-chain fatty acids (SCFA), are associated with obesity. The primary aims were to study faecal SCFA levels and the changes in SCFA levels after weight-loss interventions ...

Changes in gastrointestinal symptoms and food tolerance 6 months following weight loss surgery: associations with dietary changes, weight loss and the surgical procedure.

Kvehaugen, Anne Stine; Farup, Per Grønaas (Journal article; Peer reviewed, 2018)

Background Gastrointestinal (GI) co-morbidity is common in obese patients, but the effect of weight loss surgery on GI symptoms is incompletely elucidated. The aims of the present study were to explore changes in GI ...

Changes in serum zonulin in individuals with morbid obesity after weight-loss interventions: a prospective cohort study

Aasbrenn, Martin; Lydersen, Stian; Farup, Per Grønaas (Peer reviewed; Journal article, 2020)

Background: Zonulin is a biomarker of impaired intestinal permeability, which has been associated with various disorders. The primary aim was to study serum zonulin (s-zonulin) in individuals with morbid obesity before and ...

Circulating Lipoproteins in Subjects with Morbid Obesity Undergoing Bariatric Surgery with Gastric Bypass or Sleeve Gastrectomy

Aaseth, Jan; Rootwelt, Helge; Retterstøl, Kjetil; Hestad, Knut; Farup, Per Grønaas (Peer reviewed; Journal article, 2022)

The efficacy of various bariatric procedures on the mitigation of the obese dyslipidemia remains debated, and the impact of these measures on lipoprotein(a) (Lp(a)) levels is unknown. In this study we aimed to compare the ...

Cognitive Functions and Depression in Patients with Irritable Bowel Syndrome

Farup, Per Grønaas; Hestad, Knut (Journal article; Peer reviewed, 2015)

Background. Irritable bowel syndrome (IBS) is associated with depression and depression with impaired cognitive functions. The primary aim was to study associations between depression and cognitive functions in patients ...

Diet in subjects with irritable bowel syndrome: A cross-sectional study in the general population

Ligaarden, Solveig Catharina; Lydersen, Stian; Farup, Per Grønaas (Journal article; Peer reviewed, 2012)

Background Patients with irritable bowel syndrome (IBS) often relate symptoms to the intake of certain foods. This study assesses differences in diet in subjects with and without IBS. Methods The cross-sectional, ...

Differences in medication knowledge and risk of errors between graduating nursing students and working registered nurses: comparative study

Simonsen, Bjørg Øfstedal; Dæhlin, Gro Kvanli; Johansson, Inger Signe; Farup, Per Grønaas (Journal article; Peer reviewed, 2014)

Background: Nurses experience insufficient medication knowledge; particularly in drug dose calculations, but also in drug management and pharmacology. The weak knowledge could be a result of deficiencies in the basic ...

Differences in medication knowledge and risk of errors between graduating nursing students and working registered nurses: comparative study

Simonsen, Bjørg Øfstedal; Dæhlin, Gro Kvanli; Johansson, Inger Signe; Farup, Per Grønaas (Journal article; Peer reviewed, 2014)

Background: Nurses experience insufficient medication knowledge; particularly in drug dose calculations, but also in drug management and pharmacology. The weak knowledge could be a result of deficiencies in the basic ...