• Deforming the metric of cognitive maps distorts memory 

      Bellmund, Jacob Lukas Sarid; de Cothi, William; Ruiter, Tom; Nau, Matthias; Barry, Caswell; Doeller, Christian Fritz Andreas (Journal article, 2019)
      Environmental boundaries anchor cognitive maps that support memory. However, trapezoidal boundary geometry distorts the regular firing patterns of entorhinal grid cells, proposedly providing a metric for cognitive maps. ...
    • Hexadirectional coding of visual space in human entorhinal cortex 

      Nau, Matthias; Schröder, Tobias Navarro; Bellmund, Jacob Lukas Sarid; Doeller, Christian Fritz Andreas (Journal article; Peer reviewed, 2018)
      Entorhinal grid cells map the local environment, but their involvement beyond spatial navigation remains elusive. We examined human functional MRI responses during a highly controlled visual tracking task and show that ...
    • Hexadirectional Modulation of High-Frequency Electrophysiological Activity in the Human Anterior Medial Temporal Lobe Maps Visual Space 

      Staudigl, Tobias; Leszczynski, Marcin; Jacobs, Joshua; Sheth, Sameer A; Schroeder, Charles E.; Jensen, Ole; Doeller, Christian Fritz Andreas (Journal article; Peer reviewed, 2018)
      Grid cells are one of the core building blocks of spatial navigation [1]. Single-cell recordings of grid cells in the rodent entorhinal cortex revealed hexagonal coding of the local environment during spatial navigation ...
    • The Hippocampus Maps Concept Space, Not Feature Space 

      Theves, Stephanie; Fernández, Guillén; Doeller, Christian Fritz Andreas (Peer reviewed; Journal article, 2020)
      The hippocampal formation encodes maps of space and a key question in neuroscience is whether its spatial coding principles also provide a universal metric for the organization of nonspatial, conceptual information. Previous ...
    • How the Brain's Navigation System Shapes Our Visual Experience 

      Nau, Matthias; Julian, Joshua Benjamin; Doeller, Christian Fritz Andreas (Journal article; Peer reviewed, 2018)
      We explore the environment not only by navigating, but also by viewing our surroundings with our eyes. Here we review growing evidence that the mammalian hippocampal formation, extensively studied in the context of navigation ...
    • An immersive first-person navigation task for abstract knowledge acquisition 

      Kuhrt, Dörte; St.John, Natalie R; Bellmund, Jacob L.S.; Kaplan, Raphael; Doeller, Christian Fritz Andreas (Peer reviewed; Journal article, 2021)
      Advances in virtual reality (VR) technology have greatly benefited spatial navigation research. By presenting space in a controlled manner, changing aspects of the environment one at a time or manipulating the gain from ...
    • Knowledge Across Reference Frames: Cognitive Maps and Image Spaces 

      Bottini, Roberto; Doeller, Christian Fritz Andreas (Peer reviewed; Journal article, 2020)
      In human and non-human animals, conceptual knowledge is partially organized according to low-dimensional geometries that rely on brain structures and computations involved in spatial representations. Recently, two separate ...
    • Mapping sequence structure in the human lateral entorhinal cortex 

      Bellmund, Jacob Lukas Sarid; Deuker, Lorena; Doeller, Christian Fritz Andreas (Journal article; Peer reviewed, 2019)
      Remembering event sequences is central to episodic memory and presumably supported by the hippocampal-entorhinal region. We previously demonstrated that the hippocampus maps spatial and temporal distances between events ...
    • Navigating cognition: Spatial codes for human thinking 

      Bellmund, Jacob Lukas Sarid; Gärdenfors, Peter; Moser, Edvard Ingjald; Doeller, Christian Fritz Andreas (Journal article; Peer reviewed, 2018)
      Ever since Tolman's proposal of cognitive maps in the 1940s, the question of how spatial representations support flexible behavior has been a contentious topic. Bellmund et al. review and combine concepts from cognitive ...
    • The role of hippocampal spatial representations in contextualization and generalization of fear: Fear memory contextualization 

      de Voogd, Lycia D.; Murray, Yannick P.J.; Barte, Ramona M.; van der Heide, Anouk; Fernández, Guillén; Doeller, Christian Fritz Andreas; Hermans, Erno J. (Peer reviewed; Journal article, 2020)
      Using contextual information to predict aversive events is a critical ability that protects from generalizing fear responses to safe contexts. Animal models have demonstrated the importance of spatial context representations ...
    • Saccades are phase-locked to alpha oscillations in the occipital and medial temporal lobe during successful memory encoding 

      Staudigl, Tobias; Hartl, Elisabeth; Noachtar, Soheyl; Doeller, Christian Fritz Andreas; Jensen, Ole (Journal article; Peer reviewed, 2017)
      Efficient sampling of visual information requires a coordination of eye movements and ongoing brain oscillations. Using intracranial and magnetoencephalography (MEG) recordings, we show that saccades are locked to the phase ...
    • Sequence Memory in the Hippocampal–Entorhinal Region 

      Bellmund, Jacob Lukas Sarid; Polti, Ignacio; Doeller, Christian Fritz Andreas (Peer reviewed; Journal article, 2020)
      Episodic memories are constructed from sequences of events. When recalling such a memory, we not only recall individual events, but we also retrieve information about how the sequence of events unfolded. Here, we focus on ...
    • The Hippocampus Encodes Distances in Multidimensional Feature Space 

      Theves, Stephanie; Fernandez, Guillen; Doeller, Christian Fritz Andreas (Journal article; Peer reviewed, 2019)
      The hippocampal formation encodes maps of the physical environment [1, 2, 3, 4, 5]. A key question in neuroscience is whether its spatial coding principles also provide a universal metric for the organization of non-spatial ...
    • The role of hippocampal spatial representations in contextualization and generalization of fear 

      Lycia, D. de Voogd; Doeller, Christian Fritz Andreas; P.J.Murray, Yannick; M. Barte, Ramona; van der Heide, Anouk; Fernandez, Guillen; J. Hermans, Erno (Journal article; Peer reviewed, 2019)
      Using contextual information to predict aversive events is a critical ability that protects from generalizing fear responses to safe contexts. Animal models have demonstrated the importance of spatial context representations ...
    • Theta phase-coordinated memory reactivation reoccurs in a slow-oscillatory rhythm during NREM sleep 

      Schreiner, Thomas; Doeller, Christian Fritz Andreas; Jensen, Ole; Rasch, Björn; Staudigl, Tobias (Journal article; Peer reviewed, 2018)
      It has been proposed that sleep’s contribution to memory consolidation is to reactivate prior encoded information. To elucidate the neural mechanisms carrying reactivation-related mnemonic information, we investigated ...