Browsing NTNU Open by Author "Dobrovolska, Olena"

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Structural Analysis of Glutaredoxin Domain of Mus musculus Thioredoxin Glutathione Reductase

Dobrovolska, Olena; Shumilina, Elena; Gladyshev, Vadim N.; Dikiy, Alexander (Journal article; Peer reviewed, 2012)

Thioredoxin glutathione reductase (TGR) is a member of the mammalian thioredoxin reductase family that has a monothiol glutaredoxin (Grx) domain attached to the thioredoxin reductase module. Here, we report a structure ...
Structural Insights into Interaction between Mammalian Methionine Sulfoxide Reductase B1 and Thioredoxin

Dobrovolska, Olena; Rychkov, Georgy; Shumilina, Elena; Nerinovski, Kirill; Schmidt, Alexander; Shabalin, Konstantin; Yakimov, Alexander; Dikiy, Alexander (Journal article; Peer reviewed, 2012)

Maintenance of the cellular redox balance has vital importance for correcting organism functioning. Methionine sulfoxide reductases (Msrs) are among the key members of the cellular antioxidant defence system. To work ...
Structure-functional Characterization of Mammalian Redox Proteins: Methionine sulfoxide reductase B1 (MsrB1), Glutaredoxin domain (Grx) of TGR, and Thioredoxin (Trx)

Dobrovolska, Olena (Doktoravhandlinger ved NTNU, 1503-8181; 2013:5, Doctoral thesis, 2013)

This thesis was written at the Department of Biotechnology of Norwegian University of Science and Technology (NTNU) and made as a completion of the three-year PhD program. It summarises the studies of the thiol redox active ...