Blar i NTNU Open på forfatter "Christensen, Eidi"
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Application of Photodynamic Therapy with 5-Aminolevulinic Acid to Extracorporeal Photopheresis in the Treatment of Cutaneous T-Cell Lymphoma: A First-in-Human Phase I/II Study
Christensen, Eidi; Foss, Olav A.; Holien, Toril; Juzenas, Petras; Qian, Peng (Journal article; Peer reviewed, 2024)Extracorporeal photopheresis (ECP) is a therapeutic modality used for T-cell-mediated disorders. This approach involves exposing isolated white blood cells to photoactivatable 8-methoxypsoralen (8-MOP) and UVA light, aiming ... -
Application of photodynamic therapy with 5-aminolevulinic acid to extracorporeal photopheresis in the treatment of patients with chronic graft-versus-host disease: A first-in-human study
Christensen, Eidi; Foss, Olav A.; Quist-Paulsen, Petter; Staur, Ingrid; Pettersen, Frode; Holien, Toril; Juzenzas, Petras; Qian, Peng (Peer reviewed; Journal article, 2021)Extracorporeal photopheresis (ECP), an immunomodulatory therapy for the treatment of chronic graft-versus-host disease (cGvHD), exposes isolated white blood cells to photoactivatable 8-methoxypsoralen (8-MOP) and UVA light ... -
Aspects of selection and treatment of basal cell carcinoma for photodynamic therapy
Mørk, Erik (Doctoral theses at NTNU;2024:238, Doctoral thesis, 2024) -
Clinical versus Histological Assessment of Basal Cell Carcinoma Subtype and Thickness of Tumours Selected for Photodynamic Therapy
Mørk, Erik; Mjønes, Patricia Gjertrud; Foss, Olav A.; Mørk, Cato; Bachmann, Ingeborg Margrethe; Kroon, Susanne; Dotterud, Lars Kåre; Helsing, Per; Vatne, Øystein; Christensen, Eidi (Journal article; Peer reviewed, 2024)Photodynamic therapy is an approved treatment for primary, superficial, and small nodular basal cell carcinomas with a thickness of < 2 mm located on low-risk sites. Histologically verified basal cell carcinomas clinically ... -
Comparison Between 8-Methoxypsoralen and 5-Aminolevulinic Acid in Killing T Cells of Photopheresis Patients Ex Vivo
Holien, Toril; Gederaas, Odrun Arna; Darvekar, Sagar; Christensen, Eidi; Qian, Peng (Journal article; Peer reviewed, 2018)Background and Objective Extracorporeal photopheresis (ECP), an established modality for cutaneous T‐cell lymphoma (CTCL) and graft‐versus‐host disease, involves ex vivo treatment of isolated leukocytes of a patient with ... -
Diagnostic Accuracy in Subtyping Basal Cell Carcinoma by Clinical Diagnosis Compared with Punch Biopsy
Christensen, Eidi; Mjønes, Patricia; Grimstad, Øystein; Rørdam, Ole Martin; Foss, Olav A. (Peer reviewed; Journal article, 2016) -
Expression of β-Catenin, E-Cadherin, and α-Smooth Muscle Actin in Basal Cell Carcinoma Before Photodynamic Therapy in Non-recurrent and Recurrent Tumors: Exploring the Ability of Predicting Photodynamic Therapy outcome
Mørk, Erik; Mjønes, Patricia Gjertrud; Foss, Olav A.; Bachmann, Ingeborg Margrethe; Christensen, Eidi (Peer reviewed; Journal article, 2023)Photodynamic therapy (PDT) is an effective and cosmetically beneficial treatment of low-risk basal cell carcinomas (BCCs). To optimize PDT response, it is important to correctly select tumors. We sought to find markers ... -
Extracorporeal Photopheresis with 5-Aminolevulinic Acid in Crohn’s Disease—A First-in-Human Phase I/II Study
Espeland, Kristian; Christensen, Eidi; Aandahl, Astrid; Ulvær, Andreas; Warloe, Trond; Kleinauskas, Andrius; Darvekar, Sagar; Juzenas, Petras; Vasovic, Vlada; Qian, Peng; Jahnsen, Jørgen (Journal article; Peer reviewed, 2024)Background/Objectives: With the increasing prevalence of Crohn’s disease (CD), treatment options for patients who fail conventional and advanced therapy are highly needed. Therefore, we explored the safety and efficacy of ... -
Is there a relationship between the stratum corneum thickness and that of the viable parts of tumour cells in basal cell carcinoma?
Foss, Olav A.; Mjønes, Patricia; Fismen, Silje; Christensen, Eidi (Journal article; Peer reviewed, 2016)Basal cell carcinoma (BCC) is an invasive epithelial skin tumour. The thickness of the outermost epidermal layer of the skin, the stratum corneum (SC), influences drug uptake and penetration into tumour and may thereby ... -
New, simplified versus standard photodynamic therapy (PDT) regimen for superficial and nodular basal cell carcinoma (BCC): A single-blind, non-inferiority, randomised controlled multicentre study
Christensen, Eidi; Mørk, Erik; Foss, Olav Andreas; Mørk, Cato; Kroon, Susanne; Dotterud, Lars Kåre; Helsing, Per; Vatne, Øystein; Skogvoll, Eirik; Mjønes, Patricia Gjertrud; Bachmann, Ingeborg Margrethe (Peer reviewed; Journal article, 2024)Background Topical photodynamic therapy (PDT) is an approved and widely used treatment for low-risk basal cell carcinoma (BCC), comprising two sessions with an interval of 1 week. Simplification of the treatment course ... -
Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells
Espeland, Kristian; Kleinauskas, Andrius; Juzenas, Petras; Brech, Andreas; Darvekar, Sagar; Vasovic, Vlada; Warloe, Trond; Christensen, Eidi; Jahnsen, Jørgen; Qian, Peng (Peer reviewed; Journal article, 2022)Photodynamic therapy (PDT) with 5-aminolevulinic acid (ALA), a precursor to the potent photosensitizer, protoporphyrin IX (PpIX), is an established modality for several malignant and premalignant diseases. This treatment ... -
Photodynamic effects with 5-aminolevulinic acid on cytokines and exosomes in human peripheral blood mononuclear cells from patients with Crohn’s disease
Espeland, Kristian; Kleinauskas, Andrius; Juzenas, Petras; Darvekar, Sagar Ramesh; Vasovic, Vlada; Warloe, Trond; Christensen, Eidi; Jahnsen, Jørgen; Qian, Peng (Peer reviewed; Journal article, 2023)Photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA) which is the precursor of the photosensitizer protoporphyrin IX (PpIX) is an available treatment for several diseases. ALA-PDT induces the apoptosis and necrosis ... -
Pre-treatment Assessment of Basal Cell Carcinoma for Topical Photodynamic Therapy and Long-term Treatment Outcome
Christensen, Eidi (Doktoravhandlinger ved NTNU, 1503-8181; 2013:100, Doctoral thesis, 2013) -
Pre-Treatment Deep Curettage Can Significantly Reduce Tumour Thickness in Thick Basal Cell Carcinoma While Maintaining a Favourable Cosmetic Outcome When Used in Combination with Topical Photodynamic Therapy
Christensen, Eidi; Mørk, Cato; Foss, Olav Andreas (Journal article; Peer reviewed, 2011)Topical photodynamic therapy (PDT) has limitations in the treatment of thick skin tumours. The aim of the study was to evaluate the effect of pre-PDT deep curettage on tumour thickness in thick (≥2 mm) basal cell carcinoma ... -
Pre-treatment evaluation of basal cell carcinoma for photodynamic therapy: comparative measurement of tumour thickness in punch biopsy and excision specimens
Christensen, Eidi; Mjønes, Patricia Gjertrud; Foss, Olav Andreas; Rørdam, Ole Martin; Skogvoll, Eirik (Journal article; Peer reviewed, 2011)Tumour thickness affects the outcome of photodynamic therapy in basal cell carcinoma (BCC). The aim of this study was to evaluate whether punch biopsy provides reliable information on BCC tumour thickness, by comparing ... -
Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis
Darvekar, Sagar; Juzenas, Petras; Oksvold, Morten Pedersen; Kleinauskas, Andrius; Holien, Toril; Christensen, Eidi; Stokke, Trond; Sioud, Mouldy; Qian, Peng (Peer reviewed; Journal article, 2020)Extracorporeal photopheresis (ECP), a modality that exposes isolated leukocytes to the photosensitizer 8-methoxypsoralen (8-MOP) and ultraviolet-A (UV-A) light, is used to treat conditions such as cutaneous T-cell lymphoma ...