• 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans 

      Sønderby, Ida Elken; van der Meer, Dennis; Moreau, Clara; Kaufmann, Tobias; Walters, G. Bragi; Ellegaard, Maria; Abdellaoui, Abdel; Ames, David; Amunts, Katrin; Andersson, Micael; Armstrong, Nicola J.; Bernard, Manon; Blackburn, Nicholas B.; Blangero, John; Boomsma, Dorret I.; Brodaty, Henry; Brouwer, Rachel M.; Bülow, Robin; Bøen, Rune; Cahn, Wiepke; Calhoun, Vince D.; Caspers, Svenja; Ching, Christopher R. K.; Cichon, Sven; Ciufolini, Simone; Crespo-Facorro, Benedicto; Curran, Joanne E.; Dale, Anders M.; Dalvie, Shareefa; Dazzan, Paola; de Geus, Eco J. C.; Zubicaray, Greig I. de; Zwarte, Sonja M. C. de; Desrivieres, Sylvane; Doherty, Joanne L.; Donohoe, Gary; Draganski, Bogdan; Ehrlich, Stefan; Eising, Else; Espeseth, Thomas; Fejgin, Kim; Fisher, Simon E.; Fladby, Tormod; Frei, Oleksandr; Frouin, Vincent; Fukunaga, Masaki; Gareau, Thomas; Ge, Tian; Glahn, David C.; Grabe, Hans J.; Groenewold, Nynke A.; Gustafsson, Omar; Haavik, Jan; Haberg, Asta Kristine; Hall, Jeremy; Hashimoto, Ryota; Hehir-Kwa, Jayne Y.; Hibar, Derrek P.; Hillegers, Manon H. J.; Hoffmann, Per; Holleran, Laurena; Holmes, Avram J.; Johansson, Stefan; Jönsson, Erik Gunnar; Hellard, Stephanie Francoise Claire Le; Lundervold, Arvid; Lundervold, Astri J.; Moberget, Torgeir; Nordvik, Jan Egil; Sando, Sigrid Botne; Steen, Vidar Martin; Tamnes, Christian Krog; Agartz, Ingrid; Djurovic, Srdjan; Westlye, Lars Tjelta; Andreassen, Ole (Journal article; Peer reviewed, 2021)
      Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Human carriers ...
    • Association between polarity of first episode and solar insolation in bipolar I disorder 

      Bauer, Michael; Glenn, Tasha; Achtyes, Eric D.; Alda, Martin; Agaoglu, Esen; Altınbaş, Kürşat; Andreassen, Ole; Angelopoulos, Elias; Ardau, Raffaella; Aydin, Memduha; Ayhan, Yavuz; Baethge, Christopher; Bauer, Rita; Baune, Bernhard T.; Balaban, Ceylan; Becerra-Palars, Claudia; Behere, Aniruddh P.; Behere, Prakash B.; Belete, Habte; Belete, Tilahun; Belizario, Gabriel Okawa; Bellivier, Frank; Belmaker, Robert H.; Benedetti, Francesco; Berk, Michael; Bersudsky, Yuly; Bicakci, Şule; Birabwa-Oketcho, Harriet; Bjella, Thomas; Brady, Conan; Cabrera, Jorge; Cappucciati, Marco; Castro, Angela Marianne Paredes; Chen, Wei-Ling; Cheung, Eric Y.W.; Chiesa, Silvia; Crowe, Marie; Cuomo, Alessandro; Dallaspezia, Sara; Del Zompo, Maria; Desai, Pratikkumar; Dodd, Seetal; Etain, Bruno; Fagiolini, Andrea; Fellendorf, Frederike T.; Ferensztajn-Rochowiak, Ewa; Fiedorowicz, Jess G.; Fountoulakis, Kostas N.; Frye, Mark A.; Geoffroy, Pierre A.; Gonzalez-Pinto, Ana; Gottlieb, John F.; Grof, Paul; Haarman, Bartholomeus C.M.; Harima, Hirohiko; Hasse-Sousa, Mathias; Henry, Chantal; Høffding, Lone; Houenou, Josselin; Imbesi, Massimiliano; Isometsä, Erkki T.; Ivkovic, Maja; Janno, Sven; Johnsen, Simon; Kapczinski, Flávio; Karakatsoulis, Gregory N.; Kardell, Mathias; Kessing, Lars Vedel; Kim, Seong Jae; König, Barbara; Kot, Timur L.; Koval, Michael; Kunz, Mauricio; Lafer, Beny; Landén, Mikael; Larsen, Erik R.; Lenger, Melanie; Lewitzka, Ute; Licht, Rasmus W.; Lopez-Jaramillo, Carlos; MacKenzie, Alan; Madsen, Helle Østergaard; Madsen, Simone Alberte Kongstad A.; Mahadevan, Jayant; Mahardika, Agustine; Manchia, Mirko; Marsh, Wendy; Martinez-Cengotitabengoa, Monica; Martiny, Klaus; Mashima, Yuki; McLoughlin, Declan M.; Meesters, Ybe; Melle, Ingrid; Meza-Urzúa, Fátima; Mok, Yee Ming; Monteith, Scott; Moorthy, Muthukumaran; Morken, Gunnar; Mosca, Enrica; Mozzhegorov, Anton A.; Munoz, Rodrigo; Mythri, Starlin V.; Nacef, Fethi; Nadella, Ravi K.; Nakanotani, Takako; Nielsen, René Ernst; O'Donovan, Claire; Omrani, Adel; Osher, Yamima; Ouali, Uta; Pantovic-Stefanovic, Maja; Pariwatcharakul, Pornjira; Petite, Joanne; Pfennig, Andrea; Ruiz, Yolanda Pica; Pinna, Marco; Pompili, Maurizio; Porter, Richard; Quiroz, Danilo; Rabelo-da-Ponte, Francisco Diego; Ramesar, Raj; Rasgon, Natalie; Ratta-apha, Woraphat; Ratzenhofer, Michaela; Redahan, Maria; Reddy, M.S.; Reif, Andreas; Reininghaus, Eva Z.; Richards, Jenny Gringer; Ritter, Philipp; Rybakowski, Janusz K.; Sathyaputri, Leela; Scippa, Ângela M.; Simhandl, Christian; Smith, Daniel; Smith, José; Stackhouse, Paul W.; Stein, Dan J.; Stilwell, Kellen; Strejilevich, Sergio; Su, Kuan-Pin; Subramaniam, Mythily; Sulaiman, Ahmad Hatim; Suominen, Kirsi; Tanra, Andi J.; Tatebayashi, Yoshitaka; Teh, Wen Lin; Tondo, Leonardo; Torrent, Carla; Tuinstra, Daniel; Uchida, Takahito; Vaaler, Arne; Vieta, Eduard; Viswanath, Biju; Yoldi-Negrete, Maria; Yalcinkaya, Oguz Kaan; Young, Allan H.; Zgueb, Yosra; Whybrow, Peter C. (Peer reviewed; Journal article, 2022)
      Objective Circadian rhythm disruption is commonly observed in bipolar disorder (BD). Daylight is the most powerful signal to entrain the human circadian clock system. This exploratory study investigated if solar insolation ...
    • Associations between amygdala nuclei volumes, psychosis, psychopathy, and violent offending 

      Bell, Christina; Tesli, Natalia; Gurholt, Tiril Pedersen; Rokicki, Jaroslav; Hjell, Gabriela; Fischer-Vieler, Thomas; Melle, Ingrid; Agartz, Ingrid; Andreassen, Ole; Rasmussen, Kirsten; Johansen, Ragnhild; Friestad, Christine; Haukvik, Unn Kristin Hansen (Peer reviewed; Journal article, 2021)
      The amygdala is involved in fear perception and aggression regulation, and smaller volumes have been associated with psychotic and non-psychotic violence. We explored the relationship between amygdala nuclei volumes in ...
    • Beyond the Global Brain Differences: Intra-individual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers 

      Bøen, Rune; Kaufmann, Tobias Herbert; van der Meer, Dennis; Frei, Oleksandr; Agartz, Ingrid; Espeseth, Thomas; Håberg, Asta Kristine; Haavik, Jan; Hellard, Stephanie le; Sando, Sigrid Botne; Selbæk, Geir; Grøntvedt, Gøril Rolfseng; Westlye, Lars Tjelta; Selmer, Kaja Kristine; Alnæs, Dag; Andreassen, Ole; Sønderby, Ida Elken (Peer reviewed; Journal article, 2024)
      Background Carriers of the 1q21.1 distal and 15q11.2 BP1-BP2 copy number variants exhibit regional and global brain differences compared with noncarriers. However, interpreting regional differences is challenging if a ...
    • Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders 

      Andlauer, Till F.M.; Guzman-Parra, José; Streit, Fabian; Strohmaier, Jana; González, Maria José; Flores, Susana Gil; Fabeiro, Francisco J. Cabaleiro; Noriega, Francisco del Río; Perez, Fermin Perez; González, Jesus Haro; Diaz, Guillermo Orozco; Diego-Otero, Yolanda de; Moreno-Küstner, Berta; Auburger, Georg; Degenhardt, Franziska; Heilmann-Heimbach, Stefanie; Herms, Stefan; Hoffmann, Per; Frank, Josef; Foo, Jerome C.; Treutlein, Jens; Witt, Stephanie H.; Cichon, Sven; Kogevinas, Manolis; Bøen, Erlend; Dale, Anders M.; Djurovic, Srdjan; Elvsåshagen, Torbjørn; Reinbold, Céline Sonja; Smeland, Olav Bjerkehagen; Agartz, Ingrid; Melle, Ingrid; Ødegaard, Ketil Joachim; Stordal, Eystein; Andreassen, Ole; Rivas, Fabio; Mayoral, Fermín; Müller-Myhsok, Bertram; Forstner, Andreas J.; Nöthen, Markus M.; Rietschel, Marcella; Stahl, Eli A.; Breen, Gerome; McQuillin, Andrew; Ripke, Stephan; Trubetskoy, Vassily; Mattheisen, Manuel; Wang, Yunpeng; Morken, Gunnar; Vaaler, Arne (Peer reviewed; Journal article, 2021)
      Multiplex families with a high prevalence of a psychiatric disorder are often examined to identify rare genetic variants with large effect sizes. In the present study, we analysed whether the risk for bipolar disorder (BD) ...
    • BIPOLARVEILEDER – OPPDATERT KUNNSKAP 

      Engum, Anne; Morken, Gunnar; Vaaler, Arne; Langsrud, Knut; Ødegaard, Ketil Joachim; Syrstad, Vigdis Elin Giæver; Aminoff, Sofie Ragnhild; Engen, Magnus Johan; Lyngstad, Siv Hege; Lagerberg, Trine Vik; Andreassen, Ole (Research report, 2024)
    • Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study 

      Hughes, Amanda M.; Sanderson, Eleanor; Morris, Tim; Ayorech, Ziada; Tesli, Martin Steen; Ask, Helga; Reichborn-Kjennerud, Ted; Andreassen, Ole; Magnus, Per Minor; Helgeland, Øyvind; Johansson, Stefan; Njølstad, Pål Rasmus; Davey Smith, George; Havdahl, Alexandra Karoline Saasen; Howe, Laura D.; Davies, Neil Martin (Peer reviewed; Journal article, 2022)
      Background: Higher BMI in childhood is associated with emotional and behavioural problems, but these associations may not be causal. Results of previous genetic studies imply causal effects but may reflect influence of ...
    • Characterization of the genetic architecture of infant and early childhood body mass index 

      Helgeland, Øyvind; Vaudel, Marc; Sole-Navais, Pol; Flatley, Christopher; Juodakis, Julius; Bacelis, Jonas; Koløen, Ingvild; Knudsen, Gun Peggy Strømstad; Johansson, Bente Berg; Magnus, Per Minor; Reichborn-Kjennerud, Ted; Juliusson, Pétur Benedikt; Stoltenberg, Camilla; Holmen, Oddgeir Lingaas; Andreassen, Ole; Jacobsson, Bo; Njølstad, Pål Rasmus; Johansson, Stefan (Peer reviewed; Journal article, 2022)
      Early childhood obesity is a growing global concern; however, the role of common genetic variation on infant and child weight development is unclear. Here, we identify 46 loci associated with early childhood body mass index ...
    • Clinical Predictors of Non‐Response to Lithium Treatment in The Pharmacogenomics of Bipolar Disorder (PGBD) Study 

      Lin, Yan; Maihofer, Adam X.; Stapp, Emma; Ritchey, Megan; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H; Bertram, Holli; Bhattacharjee, Abesh; Calkin, Cynthia V.; Conroy, Carla; Coryell, William; D´Arcangelo, Nicole; DeModena, Anna; Biernacka, Joanna M.; Fisher, Carrie; Frazier, Nicole; Frye, Mark; Gao, Keming; Garnham, Julie; Gershon, Elliot; Glazer, Kara; Goes, Fernando S; Goto, Toyomi; Karberg, Elizabeth; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Lohoff, Falk W.; Stautland, Andrea; McCarthy, Michael J.; McInnis, Melvin G.; Mondimore, Francis; Morken, Gunnar; Nurnberger, John I.; Ødegaard, Ketil Joachim; Syrstad, Vigdis Elin Giæver; Ryan, Kelly; Schinagle, Martha; Schøyen, Helle Kristine; Andreassen, Ole; Shaw, Martha; Shilling, Paul D.; Slaney, Claire; Tarwater, Bruce; Calabrese, Joseph R.; Alda, Martin; Nievergelt, Caroline M.; Zandi, Peter P.; Kelsoe, John R. (Journal article; Peer reviewed, 2021)
      Background Lithium is regarded as a first-line treatment for bipolar disorder (BD), but partial response and non-response commonly occurs. There exists a need to identify lithium non-responders prior to initiating treatment. ...
    • The co-occurrence of motor and language impairments in children evaluated for autism spectrum disorder. An explorative study from Norway. 

      Reindal, Lise; Nærland, Terje; Sund, Anne Mari; Glimsdal, Birgit Avseth; Andreassen, Ole; Weidle, Bernhard (Peer reviewed; Journal article, 2022)
      Background Current research suggest that motor and language impairments are common and closely related in infants with autism spectrum disorder (ASD). In older children, less is known about how these impairments are related ...
    • Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations 

      Unnarsdóttir, Anna Bára; Lovik, Anikó; Fawns-Ritchie, Chloe; Ask, Helga; Kõiv, Kadri; Hagen, Kristen; Didriksen, Maria; Christoffersen, Lea Arregui Nordahl; Garðarsson, Alexander Berg; McIntosh, Andrew; Kähler, Anna K.; Campbell, Archie; Hauksdóttir, Arna; Erikstrup, Christian; Mikkelsen, Dorte Helenius; Altschul, Drew; Thordardottir, Edda Bjork; Frans, Emma Maria; Kvale, Gerd; Tómasson, Gunnar; Kariis, Hanna Maria; Jónsdóttir, Harpa Lind; Rúnarsdóttir, Harpa; Magnúsdóttir, Ingibjörg; Eid, Jarle; Jakobsdóttir, Jóhanna; Nielsen, Kaspar René; Kaspersen, Kathrine Agergård; Milani, Lili; Trogstad, Lill-Iren Schou; Yi, Lu; Bruun, Mie Topholm; Sullivan, Patrick F.; Magnus, Per Minor; Shen, Qing; Nesvåg, Ragnar; Brandlistuen, Ragnhild Eek; Mägi, Reedik; Ostrowski, Sisse Rye; Løkhammer, Solveig; Solem, Stian; Reichborn-Kjennerud, Ted; Hansen, Thomas Folkmann; Werge, Thomas; Aspelund, Thor; Porteous, David J.; Fang, Fang; Lehto, Kelli; Andreassen, Ole; Pedersen, Ole Birger Vesterager; Hellard, Stephanie Francoise Claire Le; Valdimarsdóttir, Unnur Anna (Journal article; Peer reviewed, 2021)
      Key features • COVIDMENT [www.covidment.is] is a NordForsk-funded research collaboration across six nations, with the overarching aim to significantly advance current knowledge on mental morbidity trajectories associated ...
    • Combining antidepressants and attention bias modification in primary health care (DEPTREAT): Protocol for a pragmatic randomized controlled trial 

      Landrø, Nils Inge; Harmer, Catherine; Blackwell, Simon E.; Bø, Ragnhild; Dawson, Gerry; Goodwin, Guy; Hagen, Hallvard Solbø; Kingslake, Jonathan; Klovning, Atle; Klungsøyr, Ole; Schjøtt-Pedersen, Olivia; Sæther, Anne Kjersti; Torgersen, Kristin Stensland; Vaaler, Arne Einar; Andreassen, Ole; Røssberg, Jan Ivar (Peer reviewed; Journal article, 2023)
      Background Major depressive disorder (MDD) is a highly prevalent psychiatric condition associated with significant disability, mortality and economic burden. A large proportion of MDD patients are treated in primary health ...
    • Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores 

      de Rojas, Itziar; Moreno-Grau, Sonia; Tesi, Niccolo; Grenier-Boley, Benjamin; Andrade, Victor; Jansen, Iris E.; Rongve, Arvid; Aarsland, Dag; Selbæk, Geir; Saltvedt, Ingvild; Sando, Sigrid Botne; Djurovic, Srdjan; Andreassen, Ole; Pedersen, Nancy L.; Stringa, Najada; Zettergren, Anna; Hernández, Isabel; Montrreal, Laura; Antunez, Carmen; Antonell, Anna; Tankard, Rick; Bis, Joshua C.; Sims, Rebecca; Bellenguez, Celine; Quintela, Inés; González-Pérez, Antonio; Calero, Miguel; Franco-Macias, Emilio; Macias, Juan; Blesa, Rafael; Cervera-Carles, Laura; Menendez-Gonzalez, Manuel; Frank-Garcia, Ana; Royo, José Luis; Moreno, Fermin; Vilas, Raquel Huerto; Baquero, Miquel; Diez-Fairen, Monica; Lage, Carmen; García-Madrona, Sebastian; Garcia-Gonzalez, Pablo; Alarcón-Martín, Emilio; Valero, Sergi; Sotolongo-Grau, Oscar; Ullgren, Abbe; Naj, Adam C.; Lemstra, Afina W.; Benaque, Alba; Perez-Cordon, Alba; Benussi, Alberto; Rabano, Alberto (Peer reviewed; Journal article, 2021)
      Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical ...
    • Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors 

      Mullins, Niamh; Kang, JooEun; Campos, Adrian I.; Coleman, Jonathan R.I.; Edwards, Alexis C.; Galfalvy, Hanga; Levey, Daniel F.; Lori, Adriana; Shabalin, Andrey A; Andreassen, Ole; Melle, Ingrid; Morken, Gunnar; Starnawska, Anna; Su, Mei-Hsin; Watson, Hunna J; Adams, Mark; Awasthi, Swapnil; Gandal, Michael; Hafferty, Jonathan; Hishimoto, Akitoyo; Kim, Minsoo; Okazaki, Satoshi; Otsuka, Ikuo; Ware, Erin B.; Stephan, Ripke; Bergen, Andrew W.; Berrettini, Wade H.; Bohus, Martin; Brandt, Harry; Chang, Xiao; Chen, Wei J; Chen, Hsi-Chung; Crawford, Steven; Crow, Scott; DiBlasi, Emily; Duriez, Philibert; Fichter, Manfred M; Fernández-Aranda, Fernando; Gallinger, Steven; Glatt, Stephen J.; Gorwood, Philip; Guo, Yiran; Hakonarson, Hakon; Halmi, Katherine A; Hwu, Hai-Gwo; Jain, Sonia; Jamain, Stephane; Jimenez-Murcia, Susana; Johnson, Craig; Djurovic, Srdjan (Peer reviewed; Journal article, 2022)
      Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic ...
    • Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools 

      Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Winsvold, Bendik K S; O'Connell, Kevin S; Frei, Oleksandr; Shadrin, Alexey; Cheng, Weiqiu; Bettella, Francesco; Rødevand, Linn; Ødegaard, Ketil Joachim; Fan, Chun C; Pirinen, Matti J; Hautakangas, Heidi M; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Tronvik, Erling Andreas; Kristoffersen, Espen Saxhaug; Zwart, John Anker Henrik; Nielsen, Jonas Bille; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Stovner, Lars Jacob; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir Lingaas; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Dale, Anders; Djurovic, Srdjan; Smeland, Olav Bjerkehagen; Andreassen, Ole (Peer reviewed; Journal article, 2022)
      Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic neurotransmission are ...
    • Educational attainment, health outcomes and mortality: a within-sibship Mendelian randomization study 

      Howe, Laurence J; Rasheed, Humaira; Jones, Paul Remy; Boomsma, Dorret I; Evans, David M; Giannelis, Alexandros; Hayward, Caroline; Hopper, John L; Hughes, Amanda; Lahtinen, Hannu; Li, Shuai; Lind, Penelope A; Martin, Nicholas G; Martikainen, Pekka; Medland, Sarah E; Morris, Tim T; Nivard, Michel G; Pingault, Jean-Baptiste; Silventoinen, Karri; Smith, Jennifer A; Willoughby, Emily A; Wilson, James F; Ahlskog, Rafael; Andreassen, Ole; Ask, Helga; Campbell, Archie; Cheesman, Rosa Catherine Gillespie; Cho, Yoonsu; Christensen, Kaare; Corfield, Elizabeth Claire; Dahm, Christina C.; Havdahl, Alexandra; Hill, William D; Kerr, Shona M; Nygaard, Marianne Rodriguez; Palviainen, Teemu; Pedersen, Nancy L; Plomin, Robert; Southey, Melissa C; Stoltenberg, Camilla; Åsvold, Bjørn Olav; Næss, Øyvind Erik; Davey Smith, George; Kaprio, Jaakko; Brumpton, Ben Michael; Davies, Neil Martin (Peer reviewed; Journal article, 2023)
      Background Previous Mendelian randomization (MR) studies using population samples (population MR) have provided evidence for beneficial effects of educational attainment on health outcomes in adulthood. However, estimates ...
    • Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs 

      Sønderby, Ida Elken; Ching, Christopher R. K.; Thomopoulos, Sophia I.; van der Meer, Dennis; Sun, Daqiang; Villalon-Reina, Julio E.; Agartz, Ingrid; Amunts, Katrin; Arango, Celso; Armstrong, Nicola J.; Ayesa-Arriola, Rosa; Bakker, Geor; Bassett, Anne S.; Boomsma, Dorret I.; Bulow, Robin; Butcher, Nancy J.; Calhoun, Vince D.; Caspers, Svenja; Chow, Eva W. C.; Cichon, Sven; Ciufolini, Simone; Craig, Michael C.; Crespo-Facorro, Benedicto; Cunningham, Adam C.; Dale, Anders M.; Dazzan, Paola; de Zubicaray, Greig I.; Djurovic, Srdjan; Doherty, Joanne L.; Donohoe, Gary; Draganski, Bogdan; Durdle, Courtney A.; Ehrlich, Stefan; Emanuel, Beverly S.; Espeseth, Thomas; Fisher, Simon E.; Ge, Tian; Glahn, David C.; Grabe, Hans J.; Gur, Raquel E.; Gutman, Boris A.; Lundervold, Astri J.; Haavik, Jan; Håberg, Asta; Hansen, Laura A.; Moberget, Torgeir; Sánchez, Jennifer Monereo; Reinbold, Céline Sonja; Tamnes, Christian Krog; Westlye, Lars Tjelta; Andreassen, Ole; et al., , (Peer reviewed; Journal article, 2021)
      The Enhancing NeuroImaging Genetics through Meta-Analysis copy number variant (ENIGMA-CNV) and 22q11.2 Deletion Syndrome Working Groups (22q-ENIGMA WGs) were created to gain insight into the involvement of genetic factors ...
    • Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness 

      Jensen, Søren Beck; Sheikh, Mashhood Ahmed; Akkouh, Ibrahim Ahmed; Szabo, Attila; O'Connell, Kevin Sean; Lekva, Tove; Engh, John; Agartz, Ingrid; Elvsåshagen, Torbjørn; Ormerod, Monica Bettina E. Greenwood; Weibell, Melissa Anne Elin Authen; Johnsen, Erik; Kroken, Rune Andreas; Melle, Ingrid; Drange, Ole Kristian; Nærland, Terje; Vaaler, Arne; Westlye, Lars Tjelta; Aukrust, Pål; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole; Ueland, Thor (Peer reviewed; Journal article, 2022)
      Abstract Background and Hypothesis Gut microbiota alterations have been reported in severe mental illness (SMI) but fewer studies have probed for signs of gut barrier disruption and inflammation. We hypothesized that ...
    • ENIGMA-Sleep: Challenges, opportunities, and the road map 

      Tahmasian, Masoud; Aleman, André; Andreassen, Ole; Arab, Zahra; Baillet, Marion; Benedetti, Francesco; Bresser, Tom; Bright, Joanna; Chee, Michael W.L.; Chylinski, Daphne; Cheng, Wei; Deantoni, Michele; Dresler, Martin; Eickhoff, Simon B.; Eickhoff, Claudia R.; Elvsåshagen, Torbjørn; Feng, Jianfeng; Foster-Dingley, Jessica C.; Ganjgahi, Habib; Grabe, Hans J.; Groenewold, Nynke A.; Ho, Tiffany C.; Bong Hong, Seung; Houenou, Josselin; Irungu, Benson; Jahanshad, Neda; Khazaie, Habibolah; Kim, Hosung; Koshmanova, Ekaterina; Kocevska, Desi; Kochunov, Peter; Lakbila-Kamal, Oti; Leerssen, Jeanne; Li, Meng; Luik, Annemarie I.; Muto, Vincenzo; Narbutas, Justinas; Nilsonne, Gustav; O’Callaghan, Victoria S.; Olsen, Alexander; Osorio, Ricardo S.; Poletti, Sara; Poudel, Govinda; Reesen, Joyce E.; Reneman, Liesbeth; Reyt, Mathilde; Riemann, Dieter; Rosenzweig, Ivana; Rostampour, Masoumeh; Saberi, Amin; Schiel, Julian; Schmidt, Christina; Schrantee, Anouk; Sciberras, Emma; Silk, Tim J.; Sim, Kang; Smevik, Hanne; Soares, Jair C.; Spiegelhalder, Kai; Stein, Dan J.; Talwar, Puneet; Tamm, Sandra; Teresi, Giana l.; Valk, Sofie L.; Van Someren, Eus; Vandewalle, Gilles; Van Egroo, Maxime; Völzke, Henry; Walter, Martin; Wassing, Rick; Weber, Frederik D.; Weihs, Antoine; Westlye, Lars Tjelta; Wright, Margaret J.; Wu, Mon-Ju; Zak, Nathalia; Zarei, Mojtaba (Peer reviewed; Journal article, 2021)
      Neuroimaging and genetics studies have advanced our understanding of the neurobiology of sleep and its disorders. However, individual studies usually have limitations to identifying consistent and reproducible effects, ...
    • European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation 

      Budu-Aggrey, Ashley; Kilanowski, Anna; Sobczyk, Maria K.; Shringarpure, Suyash S.; Mitchell, Ruth; Reis, Kadri; Reigo, Anu; Mägi, Reedik; Nelis, Mari; Tanaka, Nao; Brumpton, Ben Michael; Thomas, Laurent Francois; Sole-Navais, Pol; Flatley, Christopher; Espuela-Ortiz, Antonio; Herrera-Luis, Esther; Lominchar, Jesus V. T.; Bork-Jensen, Jette; Marenholz, Ingo; Arnau-Soler, Aleix; Jeong, Ayoung; Fawcett, Katherine A.; Baurecht, Hansjorg; Rodriguez, Elke; Alves, Alexessander Couto; Kumar, Ashish; Sleiman, Patrick M.; Chang, Xiao; Medina-Gomez, Carolina; Hu, Chen; Xu, Cheng-jian; Qi, Cancan; El-Heis, Sarah; Titcombe, Philip; Antoun, Elie; Fadista, João; Wang, Carol A.; Thiering, Elisabeth; Wu, Baojun; Kress, Sara; Kothalawala, Dilini M.; Kadalayil, Latha; Duan, Jiasong; Zhang, Hongmei; Hadebe, Sabelo; Hoffmann, Thomas; Jorgenson, Eric; Choquet, Hélène; Risch, Neil; Njølstad, Pål Rasmus; Andreassen, Ole; Johansson, Stefan; Almqvist, Catarina; Gong, Tong; Ullemar, Vilhelmina; Karlsson, Robert; Magnusson, Patrik K. E.; Szwajda, Agnieszka; Burchard, Esteban G.; Thyssen, Jacob P.; Hansen, Torben; Kårhus, Line L.; Dantoft, Thomas M.; Jeanrenaud, Alexander C.S.N.; Ghauri, Ahla; Arnold, Andreas; Homuth, Georg; Lau, Susanne; Nöthen, Markus M.; Hübner, Norbert; Imboden, Medea; Visconti, Alessia; Falchi, Mario; Bataille, Veronique; Hysi, Pirro; Ballardini, Natalia; Boomsma, Dorret I.; Hottenga, Jouke J.; Müller-Nurasyid, Martina; Ahluwalia, Tarunveer S.; Stokholm, Jakob; Chawes, Bo; Schoos, Ann-Marie M.; Esplugues, Ana; Bustamante, Mariona; Raby, Benjamin; Arshad, Syed; German, Chris; Esko, Tõnu; Milani, Lili A.; Metspalu, Andres; Terao, Chikashi; Abuabara, Katrina; Løset, Mari; Hveem, Kristian; Jacobsson, Bo; Pino-Yanes, Maria; Strachan, David P.; Grarup, Niels; Linneberg, Allan; Lee, Young-Ae; Probst-Hensch, Nicole; Weidinger, Stephan; Jarvelin, Marjo-Riitta; Melén, Erik; Hakonarson, Hakon; Irvine, Alan D.; Jarvis, Deborah; Nijsten, Tamar; Duijts, Liesbeth; Vonk, Judith M.; Koppelmann, Gerard H.; Godfrey, Keith M.; Barton, Sheila J.; Feenstra, Bjarke; Pennell, Craig E.; Sly, Peter D.; Holt, Patrick G.; Williams, L. Keoki; Bisgaard, Hans; Bønnelykke, Klaus; Curtin, John; Simpson, Angela; Murray, Clare; Schikowski, Tamara; Bunyavanich, Supinda; Weiss, Scott T.; Holloway, John W.; Min, Josine L.; Brown, Sara J.; Standl, Marie; Paternoster, Lavinia (Peer reviewed; Journal article, 2023)
      Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date (discovery ...