Browsing NTNU Open by Author "Agewall, Stefan"
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Antirheumatic therapy is associated with reduced complement activation in rheumatoid arthritis
Nguyen, Thao; Hokstad, Ingrid; Fagerland, Morten; Mollnes, Tom Eirik; Hollan, Ivana; Feinberg, Mark W.; Hjeltnes, Gunnbjørg; Eilertsen, Gro Østli; Mikkelsen, Knut; Agewall, Stefan (Journal article; Peer reviewed, 2022)Background The complement system plays an important role in pathophysiology of cardiovascular disease (CVD), and might be involved in accelerated atherogenesis in rheumatoid arthritis (RA). The role of complement activation ... -
Antirheumatic therapy is not associated with changes in circulating N-terminal pro-brain natriuretic peptide levels in patients with autoimmune arthritis
Nguyen, Thao H.P.; Fagerland, Morten; Deyab, Gia; Hjeltnes, Gunnbjørg; Hollan, Ivana; Feinberg, Mark W.; Eilertsen, Gro Østli; Mikkelsen, Knut; Agewall, Stefan (Journal article; Peer reviewed, 2021)Background: Patients with autoimmune arthritis (AA) are at increased risk for impaired cardiac function and heart failure. This may be partly due to the effect of inflammation in heart function. The impact of antirheumatic ... -
Antirheumatic treatment is associated with reduced serum Syndecan-1 in Rheumatoid Arthritis
Deyab, Gia; Reine, Trine M.; Vuong, Tram Thu; Jenssen, Trond Geir; Hjeltnes, Gunnbjørg; Agewall, Stefan; Mikkelsen, Knut; Førre, Øystein; Fagerland, Morten; Kolset, Svein Olav; Hollan, Ivana (Journal article; Peer reviewed, 2021) -
Comparative effectiveness of loop diuretics on mortality in the treatment of patients with chronic heart failure – A multicenter propensity score matched analysis
Täger, Tobias; Fröhlich, Hanna; Grundtvig, Morten; Seiz, Mirjam; Schellberg, Dieter; Goode, Kevin; Kazmi, Syed; Hole, Torstein; Katus, Hugo A.; Atar, Dan; Cleland, John G.F.; Agewall, Stefan; Clark, Andrew L.; Frankenstein, Lutz (Journal article; Peer reviewed, 2019)Background Loop diuretics are given to the majority of patients with chronic heart failure (HF). Whether the different pharmacological properties of the three guideline-recommended loop diuretics result in differential ... -
Effects of Antirheumatic Treatment on Cell Cholesterol Efflux and Loading Capacity of Serum Lipoproteins in Spondylarthropathies
Hokstad, Ingrid; Greco, Daniela; Deyab, Gia; Fagerland, Morten; Agewall, Stefan; Hjeltnes, Gunnbjørg; Zimetti, Francesca; Bernini, Franco; Ronda, Nicoletta; Hollan, Ivana (Peer reviewed; Journal article, 2022)Spondyloarthropathies (SpA) are associated with increased cardiovascular risk. Among possible mechanisms is the dysfunction of serum lipoproteins in regulating cell cholesterol homeostasis. Cholesterol efflux capacity ... -
High-sensitivity cardiac troponin T is associated with disease activity in patients with inflammatory arthritis
Nguyen, Thao; Fagerland, Morten; Hollan, Ivana; Whist, Jon Elling; Feinberg, Mark W.; Agewall, Stefan (Peer reviewed; Journal article, 2023)Objective To investigate whether high-sensitivity cardiac troponin T (hsTnT) correlates to markers of disease activity in inflammatory arthritis (IA), and whether antirheumatic treatment influences hsTnT levels. Methods We ... -
Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study
Hokstad, Ingrid; Deyab, Gia; Fagerland, Morten; Lyberg, Torstein; Hjeltnes, Gunnbjørg; Førre, Øystein Thorleiv; Agewall, Stefan; Mollnes, Tom Eirik; Hollan, Ivana (Journal article; Peer reviewed, 2019)Background The complement system is involved in pathogenesis of cardiovascular disease, and might play a role in accelerated atherogenesis in spondylarthropathies (SpA). Hence, we examined complement activation in SpA, and ...