• Adiponectin prevents orthodontic tooth movement in rats 

      Haugen, Sigrid; Aasarød, Kristin Matre; Stunes, Astrid Kamilla; Mosti, Mats Peder; Franzen, Tanya Jeanette; Vandevska-Radunovic, Vaska; Syversen, Unni; Reseland, Janne Elin (Journal article; Peer reviewed, 2017)
      Objective The objective was to examine the effects of repetitive local administration of adiponectin on experimental tooth movement in rats. Materials and methods The maxillary right first molar of male Wistar rats ...
    • Adiponectin reduces bone stiffness; verified in a 3D artificial human bone model in vitro 

      Haugen, Sigrid; He, Jianying; Sundaresan, Alamelu; Stunes, Astrid Kamilla; Aasarød, Kristin Matre; Tiainen, Hanna; Syversen, Unni; Skallerud, Bjørn Helge; Reseland, Janne Elin (Journal article; Peer reviewed, 2018)
      Primary human osteoblasts and osteoclasts incubated in a rotating coculture system without any scaffolding material, form bone-like tissue that may be used to evaluate effects of various compounds on mechanical strength. ...
    • Do patients with gastroesophageal reflux disease exhibit compromised bone quality prior to proton pump inhibitor therapy? 

      Aasarød, Kristin Matre; Mosti, Mats Peder; Finstad, Malin T.; Stunes, Astrid Kamilla; Fossmark, Reidar; Syversen, Unni (Peer reviewed; Journal article, 2021)
      Patients with gastroesophageal reflux disease (GERD) are routinely treated with proton pump inhibitors (PPIs), despite many reports of increased fracture risk associated with PPI use. Notably, the skeletal properties in ...
    • Evidence of impaired bone quality in men with type 1 diabetes: A cross-sectional study 

      Syversen, Unni; Mosti, Mats Peder; Mynarek, Ida Maria; Vedal, Trude Seselie Jahr; Aasarød, Kristin Matre; Basso, Trude; Reseland, Janne E.; Thorsby, Per Medbøe; Asvold, Bjorn O.; Eriksen, Erik Fink; Stunes, Astrid Kamilla (Peer reviewed; Journal article, 2021)
      Objective Type 1 diabetes (T1D) is associated with substantial fracture risk. Bone mineral density (BMD) is, however, only modestly reduced, suggesting impaired bone microarchitecture and/or bone material properties. Yet, ...
    • Gastric Corpus Mucosal Hyperplasia and Neuroendocrine Cell Hyperplasia, but not Spasmolytic Polypeptide-Expressing Metaplasia, Is Prevented by a Gastrin Receptor Antagonist in H+/K+ATPase Beta Subunit Knockout Mice 

      Aasarød, Kristin Matre; Waldum, Helge; Stunes, Astrid Kamilla; Sandvik, Arne Kristian; Flatberg, Arnar; Mjønes, Patricia; Syversen, Unni; Bakke, Ingunn; Fossmark, Reidar (Journal article; Peer reviewed, 2020)
      Proton pump inhibitor use is associated with an increased risk of gastric cancer, which may be mediated by hypergastrinemia. Spasmolytic polypeptide-expression metaplasia (SPEM) has been proposed as a precursor of gastric ...
    • Skeletal Effects of Gastric Hypoacidity in Mice and Humans 

      Aasarød, Kristin Matre (Doctoral theses at NTNU;2016:301, Doctoral thesis, 2016)
      Effekt av gastrisk hypoaciditet på bein hos mus og mennesker De siste tiårene har flere epidemiologiske studier vist en assosiasjon mellom bruk av syrehemmende medikamenter (protonpumpehemmere (PPI)) og frakturrisiko. ...