Blar i NTNU Open på emneord "Nanoteknologi, Bionanoteknologi"
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Addressing the barriers for delivery of liposomal nanoparticles to tumors
(Master thesis, 2018)This study concerns the enhanced delivery of three types of fluorescently labelled liposomal nanoparticles to prostate cancer xenographs. Passive delivery of the liposomes was achieved by utilizing the enhanced permeability ... -
Cellular Uptake of Nanoparticles by Sonoporation
(Master thesis, 2017)Encapsulation of anti-cancer drugs in nanoparticles (NPs) can solve many of the problems and side-effects related to cancer treatment today. By exposing micrometer-sized gas-filled bubbles to ultrasound, cellular uptake ... -
Characterization of Bioaerosols using Electron Microscopy with Special Emphasis on Airborne Bacteria
(Master thesis, 2014)Bioterrorist attacks on confined, indoor areas such as underground subway stations by the release of pathogenic microorganisms into air, could pose a threat to public safety. The potential threat may be severe not only due ... -
Depolymerisation and Characterisation of Xanthans - A study of rheological and structural properties for Enhanced Oil Recovery
(Master thesis, 2018)Xanthan is a polysaccharide which is commonly used as a thickening agent in e.g. sauces and toothpastes due to its viscosifying properties. The same attributes make it applicable for Enhanced Oil Recovery (EOR). With today's ... -
Development and Characterisation of a Nanotechnology-Enhanced Electrochemial Biosensor
(Master thesis, 2016)In the search of more sensitive and portable biological sensors for medical diagnostics, a novel electrochemical biosensor is being developed. The sensor is based on a chip with an array of ring-recessed disk electrodes, ... -
Effects of Nanopillar Arrays on Cell Motility - A Study of Cell-Nanotopography Interactions
(Master thesis, 2015)The interplay between cells and engineered high-aspect ratio nanos- tructures is emerging as an interesting and promising field within life sciences. Specific cell responses arise as a result of interactions with these ... -
Effekten av akustisk strålingskraft på levering av nanopartikler til kreftvev
(Master thesis, 2016)Ved å innkapsle kjemoterapeutiske agenter i nanopartikler kan behandling av kreft potensielt forbedres, og i kombinasjon med ultralyd kan effekten av en slik behandling økes. Ultralyd kan føre til kavitasjon av gassbobler ... -
Engineering a vascular model based on microfluidics for studying microbubbles in an acoustic field
(Master thesis, 2018)A major challenge in cancer therapy is the poor and insufficient delivery to tumour sites which many chemotherapeutic drugs face. Ultrasound (US) mediated delivery based on cavitating microbubbles (MBs) has emerged as a ... -
Expression of two Cell Membrane Proteins, CD37 and PD-L1, in Acute Myeloid Leukemia Cell Lines
(Master thesis, 2016)The standard chemotherapy treatment given to newly diagnosed Acute Myeloid Leukemia ( AML ) patients have remained practi- cally the same for the last forty years, and is poorly tolerated by the older patients. Several new ... -
Fabrication and characterization of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers
(Master thesis, 2015)The effect of drugs could be greatly improved by encapsulating drugs into nanoparticles. Nanoparticles can facilitate delivery of a variety of drugs, allow transport to target site and achieve prolonged drug delivery. This ... -
Macromolecular interactions at the single-molecule level - Fluctuation analysis of bound states
(Master thesis, 2018)The recognition, binding and release of macromolecules are precisely orchestrated in a stochastic interplay governing all enzymatic, immunological and cellular processes. Deciphering this complex synergy in order to ... -
Microfluidic Fabrication of Mineralized Alginate Hydrogel Fibers
(Master thesis, 2015)Alginates are a family of naturally occurring polysaccharides that form gels in the presence of Ca2+-ions at physiological conditions. Calcium phosphate mineralized alginates have previously been investigated as a synthetic ... -
Optimization, Cellular Uptake and Cytotoxicity of Lipid Nanoparticles
(Master thesis, 2016)Chemotherapy can potentially be greatly improved by using nanoparticles as drug carriers to deliver chemotherapeutic drugs specifically to cancer cells. Lipid nanoparticles can encapsulate hydrophobic drugs that have low ... -
Patterning of the Oxide Mask for Nanowire Growth by Dry Etching
(Master thesis, 2015)In this master s thesis it is investigated how inductively coupled plasma reactive-ion etching, in combination with hydrofluoric acid wet etching, can be used to produce consistent and reliable nanoscaled holes with a high ... -
Solid Stress and Nanoparticle Microdistribution in Xenografts: Effects of Ultrasound and Microbubble Cavitation
(Master thesis, 2018)A drug delivery system (DDS) was characterized for two different xenografts in mice: OHS and PC3. Nanoparticles (NP) encapsulating fluorescent model drugs were used as stabilizing shells around gas microbubbles (MB), and ... -
Targeting kinetics of RGD-conjugated nanoemulsions
(Master thesis, 2015)The overall aim of this project was to study targeting kinetics of fluorescently labelled RGD-conjugated nanoemulsions (RGD-NE) to avb3-expressing human umbilical vein endothelial cells, and obtain a better understanding ... -
TLR2 heterodimerisation dynamics - Establishing an advanced microscopy method to investigate protein-protein interactions
(Master thesis, 2018)In the work presented in this thesis a method for measuring the lifetime of intrinsically expressed fluorescent proteins in live cells has been demonstrated and optimised. A set of THP-1 cell lines, designed by way of viral ...