• Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST): a multicentre, open-label, randomised controlled trial. 

      Roaldsen, Melinda Berg; Eltoft, Agnethe; Wilsgaard, Tom; Christensen, Hanne; Engelter, Stefan T.; Indredavik, Bent; Jatužis, Dalius; Karelis, Guntis; Kõrv, Janika; Lundström, Erik; Petersson, Jesper; Putaala, Jukka; Søyland, Mary-Helen; Tveiten, Arnstein; Bivard, Andrew; Johnsen, Stein Harald; Mazya, Michael; Werring, David J; Wu, Teddy Y; de Marchis, Gian Marco; Robinson, Thompson G; Mathiesen, Ellisiv B (Peer reviewed; Journal article, 2022)
      Background - Current evidence supports the use of intravenous thrombolysis with alteplase in patients with wake-up stroke selected with MRI or perfusion imaging and is recommended in clinical guidelines. However, access ...
    • Statistical analysis plan for the randomized controlled trial Tenecteplase in Wake-up Ischaemic Stroke Trial (TWIST) 

      Eltoft, Agnethe; Wilsgaard, Tom; Roaldsen, Melinda Berg; Søyland, Mary-Helen; Lundström, Erik; Petersson, Jesper; Indredavik, Bent; Putaala, Jukka; Christensen, Hanne; Kõrv, Janika; Jatužis, Dalius; Engelter, Stefan T.; De Marchis, Gian Marco; Werring, David J.; Robinson, Thompson; Tveiten, Arnstein; Mathiesen, Ellisiv B. (Peer reviewed; Journal article, 2022)
      Background Patients with wake-up ischemic stroke are frequently excluded from thrombolytic treatment due to unknown symptom onset time and limited availability of advanced imaging modalities. The Tenecteplase in Wake-up ...
    • Tenecteplase in wake-up ischemic stroke trial: Protocol for a randomized-controlled trial 

      Roaldsen, Melinda Berg; Lindekleiv, Haakon; Eltoft, Agnethe; Jusufovic, Mirza; Søyland, Mary-Helen; Petersson, Jesper; Indredavik, Bent; Tveiten, Arnstein; Putaala, Jukka; Christensen, Hanne; Kõrv, Janika; Jatužis, Dalius; Engelter, Stefan T.; Marco De Marchis, Gian; Wilsgaard, Tom; Werring, David; Robinson, Thompson; Mathiesen, Ellisiv B.; Berge, Eivind (Peer reviewed; Journal article, 2021)
      Background: Patients with wake-up ischemic stroke who have evidence of salvageable tissue on advanced imaging can benefit from intravenous thrombolysis. It is not known whether patients who do not fulfil such imaging ...
    • Thrombolytic Treatment in Wake-Up Stroke: A Propensity Score-Matched Analysis of Treatment Effectiveness in the Norwegian Stroke Registry 

      Søyland, Mary-Helen; Tveiten, Arnstein; Agnethe, Eltoft; Øygarden, Halvor; Varmdal, Torunn; Indredavik, Bent; Mathiesen, Ellisiv B. (Journal article; Peer reviewed, 2024)
      Background Previous clinical trials found improved outcome of thrombolytic treatment in patients with ischemic wake‐up stroke (WUS) selected by advanced imaging techniques. The authors assessed the effectiveness of ...
    • Wake-up stroke and unknown-onset stroke; occurrence and characteristics from the nationwide Norwegian Stroke Register 

      Søyland, Mary-Helen; Tveiten, Arnstein; Eltoft, Agnethe; Øygarden, Halvor; Varmdal, Torunn; Indredavik, Bent; Mathiesen, Ellisiv B. (Journal article; Peer reviewed, 2022)
      Introduction: Population-based knowledge of the characteristics of wake-up stroke and unknown-onset stroke is limited. We compared occurrence and characteristics of ischaemic and haemorrhagic wake-up stroke, unknown-onset ...