Blar i NTNU Open på forfatter "Singleton, Amanda Holstad"
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Activation of multiple stress responses in Staphylococcus aureus substantially lowers the minimal inhibitory concentration when combining two novel antibiotic drug candidates
Singleton, Amanda Holstad; Bergum, Olaug Elisabeth Torheim; Søgaard, Caroline Krogh; Røst, Lisa M.; Olsen, Cecilie Elisabeth; Blindheim, Fredrik Heen; Ræder, Synnøve Brandt; Bjørnstad, Frithjof Andreas; Sundby, Eirik; Hoff, Bård Helge; Bruheim, Per; Otterlei, Marit (Peer reviewed; Journal article, 2023)The past few decades have been plagued by an increasing number of infections caused by antibiotic resistant bacteria. To mitigate the rise in untreatable infections, we need new antibiotics with novel targets and drug ... -
Metabolite profiling and kinetic modeling of antibiotic producing Streptomyces coelicolor in response to metabolic switching triggered by nutrient depletion
Singleton, Amanda Holstad (Master thesis, 2020)Rask framvekst av antibiotikaresistens i patogene bakteriar er ei global helsekrise. Handtering av denne krisa krev rask oppdaging og effektiv produksjon av nye antibiotiske biosyntetiske genklynger (BGC). Ein potensiell ...