Blar i NTNU Open på forfatter "Roten, Linda Tømmerdal"
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Genetic and molecular functional characterization of variants within TNFSF13B, a positional candidate preeclampsia susceptibility gene on 13q
Fenstad, Mona Høysæter; Johnson, Matthew; Roten, Linda Tømmerdal; Aas, Per Arne; Forsmo, Siri; Klepper, Kjetil; East, Christine; Abraham, Lawrence j.; Blangero, John; Brennecke, Shaun P.; Austgulen, Rigmor; Moses, Eric K (Journal article; Peer reviewed, 2010)Background: Preeclampsia is a serious pregnancy complication, demonstrating a complex pattern of inheritance. The elucidation of genetic liability to preeclampsia remains a major challenge in obstetric medicine. We have ... -
Genetic predisposition for development of preeclampsia: Candidate gene studies in the HUNT(Nord-Trøndelag Health Study) population
Roten, Linda Tømmerdal (Doktoravhandlinger ved NTNU, 1503-8181; 2009:157, Doctoral thesis, 2009)Preeclampsia is a major cause of maternal morbidity and mortality in the western world, and approximately 63,000 women dye yearly of the disease worldwide. This disorder is characterized by increased maternal blood pressure ... -
Genome-wide association scan identifies a risk locus for preeclampsia on 2q14, near the inhibin, beta B gene
Johnson, Matthew P; Brennecke, Shaun P.; East, Christine; Göring, Harald H H; Kent, Jack W; Dyer, Thomas D.; Said, Joanne M; Roten, Linda Tømmerdal; Iversen, Ann-Charlotte; Abraham, Lawrence J; Heinonen, Seppo; Kajantie, Eero; Kere, Juha; Kivinen, Katja; Pouta, Anneli; Laivuori, Hannele; Austgulen, Rigmor; Blangero, John; Moses, Eric K (Journal article; Peer reviewed, 2012)Elucidating the genetic architecture of preeclampsia is a major goal in obstetric medicine. We have performed a genome-wide association study (GWAS) for preeclampsia in unrelated Australian individuals of Caucasian ancestry ... -
The Norwegian preeclampsia family cohort study: a new resource for investigating genetic aspects and heritability of preeclampsia and related phenotypes
Roten, Linda Tømmerdal; Thomsen, Liv Cecilie Vestrheim; Gundersen, Astrid; Fenstad, Mona H.; Odland, Maria Lisa; Strand, Kristin Melheim; Solberg, Per; Tappert, Christian; Araya, Elisabeth; Bærheim, Gunhild Marie; Lyslo, Ingvill; Tollaksen, Kjersti; Bjørge, Line; Austgulen, Rigmor (Peer reviewed; Journal article, 2015)Background:Preeclampsia is a major pregnancy complication without curative treatment available. A NorwegianPreeclampsia Family Cohort was established to provide a new resource for genetic and molecular studies aiming ... -
Preeclampsia and cardiovascular disease share genetic risk factors on chromosome 2q22
Løset, Mari; Johnson, Matthew P.; Melton, Philip E.; Ang, Wei; Huang, Rae-Chi; Mori, Trevor; Beilin, Lawrence J.; Pennell, Craig E.; Roten, Linda Tømmerdal; Iversen, Ann-Charlotte; Austgulen, Rigmor; East, Christine E.; Blangero, John; Brennecke, Shaun P.; Moses, Eric K (Journal article; Peer reviewed, 2014)Objective Four putative single nucleotide polymorphism (SNP) risk variants at the preeclampsia susceptibility locus on chromosome 2q22; rs2322659 (LCT), rs35821928 (LRP1B), rs115015150 (RND3) and rs17783344 (GCA), were ... -
Refined phenotyping identifies links between preeclampsia and related diseases in a Norwegian preeclampsia family cohort
Thomsen, Liv Cecilie Vestrheim; Melton, Philip E.; Tollaksen, Kjersti; Lyslo, Ingvill; Roten, Linda Tømmerdal; Odland, Maria Lisa; Strand, Kristin Melheim; Nygård, Ottar; Sun, Chen; Iversen, Ann-Charlotte; Austgulen, Rigmor; Moses, Eric; Bjørge, Line (Peer reviewed; Journal article, 2015)Objective: Preeclampsia is a complex genetic disease of pregnancy with a heterogenous presentation, unknown cause and potential severe outcomes for both mother and child. Preeclamptic women have increased risk for ... -
Research based on existing clinical data and biospecimens: a systematic study of patients’ opinions
Eikemo, Hilde; Roten, Linda Tømmerdal; Vaaler, Arne (Peer reviewed; Journal article, 2022)Background The aim of the present survey was to investigate newly discharged hospital patients’ opinions on secondary use of their hospital data and biospecimens within the context of health research in general and, ... -
STOX2 but not STOX1 is differently expressed in preeclampstic decidua from Norwegian women: data from the Second Nord-Trondelag Health Study
Fenstad, Mona Høysæter; Johnson, Matthew; Løset, Mari; Mundal, Siv Boon; Roten, Linda Tømmerdal; Eide, Irina Poliakova; Bjørge, Line; Sande, Ragnar; Johansson, Åsa; Dyer, T D; Forsmo, Siri; Blangero, John; Moses, E K; Austgulen, Rigmor (Journal article; Peer reviewed, 2010)