• Complement Is Activated During Normothermic Machine Perfusion of Porcine and Human Discarded Kidneys 

      Jager, Neeltina M.; Venema, Leonie H.; Arykbaeva, Asel S.; Meter-Arkema, Anita H.; Ottens, Petra J.; van Kooten, Cees; Mollnes, Tom Eirik; Alwayn, Ian P. J.; Leuvenink, Henri G. D.; Pischke, Soeren (Peer reviewed; Journal article, 2022)
      Background: The gap between demand and supply of kidneys for transplantation necessitates the use of kidneys from extended criteria donors. Transplantation of these donor kidneys is associated with inferior results, reflected ...
    • H2S-Enriched Flush out Does Not Increase Donor Organ Quality in a Porcine Kidney Perfusion Model 

      Maassen, Hanno; Venema, Leonie H.; Weiss, Marc G.; Huijink, Tobias M.; Hofker, H. Sijbrand; Keller, Anna K.; Mollnes, Tom Eirik; Eijken, Marco; Pischke, Soeren; Jespersen, Bente; van Goor, Harry; Leuvenink, Henri G. D. (Peer reviewed; Journal article, 2023)
      Kidney extraction time has a detrimental effect on post-transplantation outcome. This study aims to improve the flush-out and potentially decrease ischemic injury by the addition of hydrogen sulphide (H2S) to the flush ...