Blar i NTNU Open på forfatter "Klaharn, Merisa"
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Characterization of birinapant-induced cell death in human monocytes and macrophage subtypes
Klaharn, Merisa (Master thesis, 2019)Macrophages play various roles in the body depending on the environment they reside due to their diversity and plasticity. Distinct functional phenotypes operate specific tasks, ranging from inflammation and host defense ... -
Smac-mimetics reduce numbers and viability of human osteoclasts
Moen, Ingrid Nyhus; Westhrin, Marita; Håland, Erling; Haug, Markus; Nonstad, Unni; Klaharn, Merisa; Standal, Therese; Starheim, Kristian K. (Peer reviewed; Journal article, 2021)Elevated activity of bone-degrading osteoclasts (OC) contributes to pathological bone degradation in diseases such as multiple myeloma. Several proinflammatory cytokines, including TNF, contribute to osteoclastogenesis. ...