Blar i NTNU Open på forfatter "Kalbacher, Hubert"
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Mutations in the substrate binding site of human heat-shock protein 70 indicate specific interaction with HLA-DR outside the peptide binding groove
Rohrer, Karin; Haug, Markus; Schwoerer, Daniela; Kalbacher, Hubert; Holzer, Ursula (Journal article; Peer reviewed, 2014)Heat-shock protein 70 (Hsp70)–peptide complexes are involved in MHC class I- and II-restricted antigen presentation, enabling enhanced activation of T cells. As shown previously, mammalian cytosolic Hsp70 (Hsc70) molecules ...